Programmbereich Asthma und Allergie

Angeborene Immunität

Mission    Projekte    Drittmittel    Methoden    Publikationen    Mitarbeiter/innen

Publikationen

2020

Herster, F, Bittner, Z, Archer, NK, Dickhöfer, S, Eisel, D, Eigenbrod, T, Knorpp, T, Schneiderhan-Marra, N, Löffler, MW, Kalbacher, H, Vierbuchen, T, Heine, H, Miller, LS, Hartl, D, Freund, L, Schäkel, K, Heister, M, Ghoreschi, K & Weber, ANR 2020, 'Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis', Nature communications, Jg. 11, Nr. 1, S. 1-13. https://doi.org/10.1038/s41467-019-13756-4

Komaniecka, I, Susniak, K, Chroma, A, Heine, H & Holst, O 2020, 'The Lipid A from the Lipopolysaccharide of the Phototrophic Bacterium Rhodomicrobium vannielii ATCC 17100 Revisited', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Jg. 22, Nr. 1. https://doi.org/10.3390/ijms22010258

Wang, Z, Minarsch, E-ML, Kublik, S, Heine, H, Schloter, M & Foesel, BU 2020, 'Complete Genome Sequence of Lactococcus lactis subsp. lactis G121, an Isolate with Allergy-Protective Features Derived from a Farming Environment', Microbiology resource announcements, Jg. 9, Nr. 41. https://doi.org/10.1128/MRA.00777-20

Zamyatina, A & Heine, H 2020, 'Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways', FRONTIERS IN IMMUNOLOGY, Jg. 11, S. 585146. https://doi.org/10.3389/fimmu.2020.585146

 

2019

Bossen J, Uliczka K, Steen L, Pfefferkorn R, Mai MM, Burkhardt L, Spohn M, Bruchhaus I, Fink C, Heine H, Roeder T: An EGFR-Induced Drosophila Lung Tumor Model Identifies Alternative Combination Treatments. Mol Cancer Ther 2019, 18(9):1659-1668.

Freund I, Buhl DK, Boutin S, Kotter A, Pichot F, Marchand V, Vierbuchen T, Heine H, Motorin Y, Helm M, Dalpke AH, Eigenbrod T: 2'-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms. Rna 2019, 25(7):869-880.

Jappe U, Schwager C, Schromm AB, Gonzalez Roldan N, Stein K, Heine H, Duda KA: Lipophilic Allergens, Different Modes of Allergen-Lipid Interaction and Their Impact on Asthma and Allergy. Front Immunol 2019, 10:122.

Vierbuchen T, Stein K, Heine H: RNA is taking its Toll: Impact of RNA-specific Toll-like receptors on health and disease. Allergy 2019, 74(2):223-235.

 

2018

Adanitsch, F, Shi, J, Shao, F, Beyaert, R, Heine, H & Zamyatina, A 2018, 'Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics' Journal of Physical Chemistry B, Bd 9, Nr. 16, S. 3957-3963. DOI: 10.1039/c7sc05323a

Borio A, Holgado A, Garate JA, Beyaert R, Heine H, Zamyatina A, ‘Disaccharide-Based Anionic Amphiphiles as Potent Inhibitors of Lipopolysaccharide-Induced Inflammation’. ChemMedChem 2018, 13(21):2317-2331.

Vierbuchen, T., Stein, K., Hein, H., ‘RNA is taking its Toll - Impact of RNA-specific Toll-like receptors on health and disease’. Allergy 2018 Nov 26. doi: 10.1111/all.13680. [Epub ahead of print].

 

2017

Gorczynski, RM, Alexander, C, Brandenburg, K, Chen, Z, Heini, A, Heumann, D, Mach, J-P, Rietschel, ET, Ulmer, AJ, Zähringer, U, Yu, K & Khatri, I 2017, 'An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression' INTERNATIONAL IMMUNOPHARMACOLOGY , Bd 50, Nr. (2017), S. 69-76.

Lindner, K, Ströbele, M, Schlick, S, Webering, S, Jenckel, A, Kopf, J, Danov, O, Sewald, K, Buj, C, Creutzenberg, O, Tillmann, T, Pohlmann, G, Ernst, H, Ziemann, C, Hüttmann, G, Heine, H, Bockhorn, H, Hansen, T, König, P & Fehrenbach, H 2017, 'Biological effects of carbon black nanoparticles are changed by surface coating with polycyclic aromatic hydrocarbons' Particle and Fibre Toxicology, Bd 14, Nr. 1, S. 8. DOI: 10.1186/s12989-017-0189-1

Stein, K, Brand, S, Jenckel, A, Sigmund, A, Chen, ZJ, Kirschning, CJ, Kauth, M & Heine, H 2017, 'Endosomal recognition of Lactococcus lactis G121 and its RNA by dendritic cells is key to its allergy-protective effects' The Journal of allergy and clinical immunology, Bd 139, Nr. 2, S. 667-678. DOI: 10.1016/j.jaci.2016.06.018

Bang, C, Vierbuchen, T, Gutsmann, T, Heine, H & Schmitz, RA 2017, 'Immunogenic properties of the human gut-associated archaeon Methanomassiliicoccus luminyensis and its susceptibility to antimicrobial peptides' PLOS ONE, Bd 12, Nr. 10, S. e0185919. DOI: 10.1371/journal.pone.0185919

Jatzlauk, G, Bartel, S, Heine, H, Schloter, M & Krauss-Etschmann, S 2017, 'Influences of environmental bacteria and their metabolites on allergies, asthma and host microbiota' ALLERGY, Bd 72, Nr. 12, S. 1859-1867. DOI: 10.1111/all.13220

Pooe, OJ, Köllisch, G, Heine, H & Shonhai, A 2017, 'Plasmodium falciparum heat shock protein 70 lacks immune modulatory activity' PROTEIN AND PEPTIDE LETTERS, Bd 24, Nr. 6, S. 503-510. DOI: 10.2174/0929866524666170214141909