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Fluoreszenz-Zytometrie

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Publikationen

2018

Erdmann H, Behrends J, Ritter K, Hölscher A, Volz J, Rosenkrands I, Hölscher C. The increased protection and pathology in Mycobacterium tuberculosis-infected  IL-27R-alpha-deficient mice is supported by IL-17A and is associated with the  IL-17A-induced expansion of multifunctional T cells. Mucosal Immunol. 2018 May 4.doi: 10.1038/s41385-018-0026-3. [Epub ahead of print] PubMed PMID: 29728641.

Stüve P, Minarrieta L, Erdmann H, Arnold-Schrauf C, Swallow M, Guderian M,  Krull F, Hölscher A, Ghorbani P, Behrends J, Abraham WR, Hölscher C, Sparwasser  TD, Berod L. De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a  Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages. Front Immunol. 2018 Apr 5;9:495. doi: 10.3389/fimmu.2018.00495. eCollection 2018. PubMed PMID: 29675017; PubMed Central PMCID: PMC5895737.

Schocker F, Recke A, Kull S, Worm M, Behrends J, Jappe U. Reply to Chirumbolo et al. Pediatr Allergy Immunol. 2018 Jun;29(4):461-462. doi: 10.1111/pai.12892. Epub 2018 Apr 22. PubMed PMID: 29542182.

Yu X, Akbarzadeh R, Pieper M, Scholzen T, Gehrig S, Schultz C, Zillikens D, König P, Petersen F.Neutrophil Adhesion Is a Prerequisite for Antibody-Mediated Proteolytic Tissue Damage in Experimental Models of Epidermolysis Bullosa Acquisita. J Invest Dermatol. 2018 Mar 17. pii: S0022-202X(18)31729-9. doi: 10.1016/j.jid.2018.03.1499. [Epub ahead of print] PubMed PMID: 29559343.

Scholzen T, Gerlach C, Cattoretti G. An insider's view on how Ki-67, the bright beacon of cell proliferation, became very popular.A tribute to Johannes Gerdes (1950 - 2016). Histopathology. 2018 Mar 11. doi: 10.1111/his.13511. [Epub ahead of print] PubMed PMID: 29526027.

2017

Offermann A, Vlasic I, Syring I, Vogel W, Ruiz C, Zellweger T, Rentsch CA, Hagedorn S, Behrends J, Nowak M, Merseburger A, Bubendorf L, Kirfel J, Duensing S, Shaikhibrahim Z, Perner S. MED15 overexpression in prostate cancer arises
during androgen deprivation therapy via PI3K/mTOR signaling. Oncotarget. 2017 Jan 31;8(5):7964-7976. doi: 10.18632/oncotarget.13860. PubMed PMID: 27974704; PubMed Central PMCID: PMC5352374.

Schmok E, Abad Dar M, Behrends J, Erdmann H, Rückerl D, Endermann T, Heitmann L, Hessmann M, Yoshimura A, Rose-John S, Scheller J, Schaible UE, Ehlers S, Lang R, Hölscher C. Suppressor of Cytokine Signaling 3 in Macrophages Prevents Exacerbated Interleukin-6-Dependent Arginase-1 Activity and Early Permissiveness to Experimental Tuberculosis. Front Immunol. 2017 Nov 10; 8:1537. doi: 10.3389/fimmu.2017.01537.

Schwager C, Kull S, Behrends J, Röckendorf N, Schocker F, Frey A, Homann A, Becker WM, Jappe U. Peanut oleosins associated with severe peanut allergy - Importance of lipophilic allergens for comprehensive allergy diagnostics. J Allergy Clin Immunol. 2017 Mar 22. pii: S0091-6749(17)30417-7. doi: 10.1016/j.jaci.2017.02.020. [Epub ahead of print] PubMed PMID: 28342912.

 

2016

Offermann A, Vlasic I, Syring I, Vogel W, Ruiz C, Zellweger T, Rentsch CA, Hagedorn S, Behrends J, Nowak M, Merseburger A, Bubendorf L, Kirfel J, Duensing  S, Shaikhibrahim Z, Perner S. MED15 overexpression in prostate cancer arises  during androgen deprivation therapy via PI3K/mTOR signaling. Oncotarget. 2016 Dec 10. doi: 10.18632/oncotarget.13860. [Epub ahead of print] PubMed PMID: 27974704.

Wang S, Hüttmann G, Scholzen T, Zhang Z, Vogel A, Hasan T, Rahmanzadeh R. A light-controlled switch after dual targeting of proliferating tumor cells via the membrane receptor EGFR and the nuclear protein Ki-67. Sci Rep. 2016 Jun 1;6:27032. doi: 10.1038/srep27032. 

Erdmann H, Behrends J, Hölscher C. During acute experimental infection with the reticulotropic Trypanosoma cruzi strain Tulahuen IL-22 is induced IL-23-dependently but is dispensable for protection. Scientific Reports. 2016;6:32927. doi:10.1038/srep32927.

Böhme J, Roßnagel C, Jacobs T, Behrends J, Hölscher C, Erdmann H. ‚Epstein-Barr virus-induced gene 3 suppresses T helper type 1, type 17 and type 2 immune responses after Trypanosoma cruzi infection and inhibits parasite replication by interfering with alternative macrophage activation.‘, Immunology. 2016 Mar;147(3):338-48. doi: 10.1111/imm.12565.

Blank J, Eggers L, Behrends J, Jacobs T, Schneider BE., ‚One Episode of Self-Resolving Plasmodium yoelii Infection Transiently Exacerbates Chronic Mycobacterium tuberculosis Infection.‘, Front Microbiol. 2016 Feb 15;7:152. doi: 10.3389/fmicb.2016.00152. eCollection 2016.

 

2015

Böhme J, Roßnagel C, Jacobs T, Behrends J, Hölscher C, Erdmann H. EBI3 suppresses Th1, Th17 and Th2 immune responses after Trypanosoma cruzi infection and inhibits parasite replication by interfering with alternative macrophage activation. Immunology. 2015 Dec 23. doi: 10.1111/imm.12565. [Epub ahead of print]

Blank J, Behrends J, Jacobs T, Schneider BE. 2016. Mycobacterium tuberculosis coinfection has no impact on Plasmodium berghei ANKA-induced experimental cerebral malaria in C57BL/6 mice. Infect Immun. 2015 Dec 7;84(2):502-10. doi: 10.1128/IAI.01290-15.

Lewis MD, Behrends J, Sá E Cunha C, Mendes AM, Lasitschka F, Sattler JM, Heiss K, Kooij TW, Prudêncio M, Bringmann G, Frischknecht F, Mueller AK. Chemical attenuation of Plasmodium in the liver modulates severe malaria disease progression. J Immunol. 2015 May 15;194(10):4860-70. doi: 10.4049/jimmunol.1400863. Epub 2015 Apr 10.

Lunding LP, Webering S, Vock C, Behrends J, Wagner C, Hölscher C, Fehrenbach H, Wegmann M. Poly(inosinic-cytidylic) Acid-Triggered Exacerbation of Experimental Asthma Depends on IL-17A Produced by NK Cells. J Immunol. 2015 May 13. pii: 1402529. [Epub ahead of print]

 

2014

Heinbockel L, Palacios-Chaves L, Alexander C, Rietschel E, Behrends J, Correa
W, Fukuoka S, Gutsmann T, Ulmer AJ, Brandenburg K. Mechanism of Hbγ-35-induced anincrease in the activation of the human immune system by endotoxins. Innate Immun. 2014 Jul 16. pii: 1753425914535957. [Epub ahead of print]

Schneider BE, Behrends J, Hagens K, Harmel N, Shayman JA, Schaible UE. Lysosomal phospholipase A2: A novel player in host immunity to Mycbacterium tuberculosis. EUROPEAN JOURNAL of IMMUNOLOGY 2014;
DOI: 10.1002/eji.201244383

Mueller AK, Behrends J, Blank J, Schaible UE, Schneider BE. An experimental
model to study tuberculosis-malaria coinfection upon natural transmission of
Mycobacterium tuberculosis and Plasmodium berghei. J Vis Exp. 2014 Feb
17;(84):e50829. doi: 10.3791/50829. PubMed PMID: 24637905

Correa W, Manrique-Moreno M, Behrends J, Patiño E, Marella C, Peláez-Jaramillo
C, Garidel P, Gutsmann T, Brandenburg K, Heinbockel L. Galleria mellonella native and analogue peptides Gm1 and ΔGm1. II) Anti-bacterial and anti-endotoxic effects. Biochim Biophys Acta. 2014 Oct;1838(10):2739-44. doi:
10.1016/j.bbamem.2014.07.005. Epub 2014 Jul 10.

Berod L, Stüve P, Varela F, Behrends J, Swallow M, Kruse F, Krull F, Ghorbani
P, Mayer CT, Hölscher C, Sparwasser T. Rapid Rebound of the Treg Compartment in DEREG Mice Limits the Impact of Treg Depletion on Mycobacterial Burden, but Prevents Autoimmunity. PLoS One. 2014 Jul 22;9(7):e102804. doi:10.1371/journal.pone.0102804. eCollection 2014.

Heitmann L, Abad Dar M, Schreiber T, Erdmann H, Behrends J, Mckenzie AN,
Brombacher F, Ehlers S, Hölscher C. The IL-13/IL-4Rα axis is involved in
tuberculosis-associated pathology. J Pathol. 2014 Jun 30. doi: 10.1002/path.4399. [Epub ahead of print]

 

2013

Behrends J, Renauld JC, Ehlers S, Hölscher C. IL-22 is mainly produced by
IFNγ-secreting cells but is dispensable for host protection against Mycobacterium tuberculosis infection. PLoS One. 2013;8(2):e57379. doi:
10.1371/journal.pone.0057379. Epub 2013 Feb 27. PubMed PMID: 23460846; PubMed Central PMCID: PMC3583848.

 

2012

Mueller AK, Behrends J, Hagens K, Mahlo J, Schaible UE, Schneider BE. Natural
transmission of Plasmodium berghei exacerbates chronic tuberculosis in an
experimental co-infection model. PLoS One. 2012;7(10):e48110. doi: 10.1371/journal.pone.0048110. Epub 2012 Oct 26. PubMed PMID: 23110184; PubMedCentral PMCID: PMC3482195.

Everts, B, Hussaarts, L, Driessen, NN, Meevissen, MHJ, Schramm, G, van der Ham, AJ, van der Hoeven, B, Scholzen, T, Burgdorf, S, Mohrs, M, Pearce, EJ, Hokke, CH, Haas, H, Smits, HH & Yazdanbakhsh, M 2012, 'Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor' JOURNAL OF EXPERIMENTAL MEDICINE, Bd 209, Nr. 10, S. 1753-1767., 10.1084/jem.20111381 

 

2011

Kaur, I, Schramm, G, Everts, B, Scholzen, T, Kindle, KB, Beetz, C, Montiel-Duarte, C, Blindow, S, Jones, AT, Haas, H, Stolnik, S, Heery, DM & Falcone, FH 2011, 'Interleukin-4-inducing principle from Schistosoma mansoni eggs contains a functional C-terminal nuclear localization signal necessary for nuclear translocation in mammalian cells but not for its uptake' Infection and immunity, Bd 79, Nr. 4, S. 1779-88., 10.1128/IAI.01048-10

Sodenkamp J, Behrends J, Förster I, Müller W, Ehlers S, Hölscher C. gp130 on
macrophages/granulocytes modulates inflammation during experimental tuberculosis. Eur J Cell Biol. 2011 Jun-Jul;90(6-7):505-14. doi: 10.1016/j.ejcb.2010.10.010. Epub 2010 Dec 8. Review. PubMed PMID: 21144615.

 

2010

Lindner, U, Kramer, J, Behrends, J, Driller, B, Wendler, N-O, Boehrnsen, F, Rohwedel, J & Schlenke, P 2010, 'Improved proliferation and differentiation capacity of human mesenchymal stromal cells cultured with basement-membrane extracellular matrix proteins' Cytotherapy, Bd 12, Nr. 8, S. 992-1005., 10.3109/14653249.2010.510503

 

2009

Karsten CM, Behrends J, Wagner AK, Fuchs F, Figge J, Schmudde I, Hellberg L,
Kruse A. DC within the pregnant mouse uterus influence growth and functional
properties of uterine NK cells. Eur J Immunol. 2009 Aug;39(8):2203-14. doi:
10.1002/eji.200838844.

2008

Behrends J, Karsten CM, Wilke S, Röbke A, Kruse A. Identification of ITGA4/ITGB7 and ITGAE/ITGB7 expressing subsets of decidual dendritic-like cells
within distinct microdomains of the pregnant mouse uterus. Biol Reprod. 2008
Oct;79(4):624-32. doi: 10.1095/biolreprod.107.067041. Epub 2008 Jun 18.