Priority Research Area Infections

2023

Doijad SP, Gisch N, Frantz R, Kumbhar BV, Falgenhauer J, Imirzalioglu C, Falgenhauer L, Mischnik A, Rupp J, Behnke M, Buhl M, Eisenbeis S, Gastmeier P, Gölz H, Häcker GA, Käding N, Kern WV, Kola A, Kramme E, Peter S, Rohde AM, Seifert H, Tacconelli E, Vehreschild MJGT, Walker SV, Zweigner J, Schwudke D; DZIF R-Net Study Group; Chakraborty T 2023,  'Resolving colistin resistance and heteroresistance in Enterobacter species', Nat Commun, Jg. 14, Nr. 1, S. 140. https://doi:10.1038/s41467-022-35717-0.

Frantz R, Gwozdzinski K, Gisch N, Doijad SP, Hudel M, Wille M, Abu Mraheil M, Schwudke D, Imirzalioglu C, Falgenhauer L, Ehrmann M, Chakraborty T. 2023,  'A Single Residue within the MCR-1 Protein Confers Anticipatory Resilience. ', Microbiol Spectr. 2023 Apr 18:e0359222., doi: 10.1128/spectrum.03592-22., PMID: 37071007

Minhas V, Domenech A, Synefiaridou D, Straume D, Brendel M, Cebrero G, Liu X, Costa C, Baldry M, Sirard JC, Perez C, Gisch N, Hammerschmidt S, Håvarstein LS, Veening JW 2023, 'Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence', PLoS Biol.,  Jg. 21, Nr. 1, e3001990. https://doi:10.1371/journal.pbio.3001990.

Schwudke D. 2023 'What information is contained in experimentally determined lipid profiles?', Frontiers in Analytical Science  3, 13

Buchkapitel / Book Chapter:

Kopczynski D, Krause D, Al Machot F, Schwudke D, Hoffmann N, Ahrends R. 2023, 'The Past and Future of Lipidomics Bioinformatics.', Mass Spectrometry for Lipidomics: Methods and Applications 1, 271-290, https://doi.org/10.1002/9783527836512.ch10

 

2022

Brandenburg J, Heyckendorf J, Marwitz F, Zehethofer N, Linnemann L, Gisch N, Karaköse H, Reimann M, Kranzer K, Kalsdorf B, Sanchez-Carballo P, Weinkauf M, Scholz V, Malm S, Homolka S, Gaede KI, Herzmann C, Schaible UE, Hölscher C, Reiling N, Schwudke D 2022, 'Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis', ACS Infect Dis., Jg. 8, Nr. 7, S. 1303-1315. https://doi.org/10.1021/acsinfecdis.2c00075

Dannenberger D, Eggert A, Kalbe C, Woitalla A, Schwudke D. 2022, 'Are n-3 PUFAs from Microalgae Incorporated into Membrane and Storage Lipids in Pig Muscle Tissues?-A Lipidomic Approach', ACS Omega, Jg. 7, Nr. 28, S. 24785-24794. https://doi.org/10.1021/acsomega.2c02476

Gerster, T, Wröbel, M, Hofstaedter, CE, Schwudke, D, Ernst, RK, Ranf, S & Gisch, N 2022, 'Remodeling of Lipid A in Pseudomonas syringae pv. phaseolicola In Vitro', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Jg. 23, Nr. 4, 1996. https://doi.org/10.3390/ijms23041996

Gisch, N, Utpatel, C, Gronbach, LM, Kohl, TA, Schombel, U, Malm, S, Dobos, KM, Hesser, DC, Diel, R, Götsch, U, Gerdes, S, Shuaib, YA, Ntinginya, NE, Khosa, C, Viegas, S, Kerubo, G, Ali, S, Al-Hajoj, SA, Ndung’u, PW, Rachow, A, Hoelscher, M, Maurer, FP, Schwudke, D, Niemann, S, Reiling, N & Homolka, S 2022, 'Sub-Lineage Specific Phenolic Glycolipid Patterns in the Mycobacterium tuberculosis Complex Lineage 1', Frontiers in Microbiology, Jg. 13, S. 832054. https://www.frontiersin.org/article/10.3389/fmicb.2022.832054

Heidler von Heilborn, D, Nover, L-L, Weber, M, Hölzl, G, Gisch, N, Waldhans, C, Mittler, M, Kreyenschmidt, J, Woehle, C, Hüttel, B & Lipski, A 2022, 'Polar lipid characterization and description of Chryseobacterium capnotolerans sp. nov., isolated from high CO2-containing atmosphere and emended descriptions of the genus Chryseobacterium, and the species C. balustinum, C. daecheongense, C. formosense, C. gleum, C. indologenes, C. joostei, C. scophthalmum and C. ureilyticum', INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Jg. 72, Nr. 5. https://doi.org/10.1099/ijsem.0.005372

Hoffmann N, Mayer G, Has C, Kopczynski D, Al Machot F, Schwudke D, Ahrends R, Marcus K, Eisenacher M, Turewicz M 2022, 'A Current Encyclopedia of Bioinformatics Tools, Data Formats and Resources for Mass Spectrometry Lipidomics', Metabolites, Jg. 12, Nr. 7, S. 584. https://doi.org/10.3390/metabo12070584

Huck, BC, Thiyagarajan, D, Bali, A, Boese, A, Besecke, KFW, Hozsa, C, Gieseler, RK, Furch, M, Carvalho-Wodarz, C, Waldow, F, Schwudke, D, Metelkina, O, Titz, A, Huwer, H, Schwarzkopf, K, Hoppstädter, J, Kiemer, AK, Koch, M, Loretz, B & Lehr, C-M 2022, 'Nano-in-Microparticles for Aerosol Delivery of Antibiotic-loaded, Fucose-derivatized and Macrophage-targeted Liposomes to Combat Mycobacterial Infections: In Vitro deposition, Pulmonary Barrier Interactions and Targeted Delivery', Advanced healthcare materials, S. e2102117. https://doi.org/10.1002/adhm.202102117

Kupsch, S, Eggers, LF, Spengler, D, Gisch, N, Goldmann, T, Fehrenbach, H, Stichtenoth, G, Krause, MF, Schwudke, D & Schromm, AB 2022, 'Characterization of phospholipid-modified lung surfactant in vitro and in a neonatal ARDS model reveals anti-inflammatory potential and surfactant lipidome signatures', European journal of pharmaceutical sciences, Jg. 175, S. 106216. https://doi.org/10.1016/j.ejps.2022.106216

McDonald JG, Ejsing CS, Kopczynski D, Holčapek M, Aoki J, Arita M, Arita M, Baker ES, Bertrand-Michel J, Bowden JA, Brügger B, Ellis SR, Fedorova M, Griffiths WJ, Han X, Hartler J, Hoffmann N, Koelmel JP, Köfeler HC, Mitchell TW, O'Donnell VB, Saigusa D, Schwudke D, Shevchenko A, Ulmer CZ, Wenk MR, Witting M, Wolrab D, Xia Y, Ahrends R, Liebisch G, Ekroos K 'Introducing the Lipidomics Minimal Reporting Checklist', Nat. Metab. 2022 Aug 8. Online ahead of print. https://doi.org/10.1038/s42255-022-00628-3

Öhlmann, S, Krieger, A-K, Gisch, N, Meurer, M, de Buhr, N, von Köckritz-Blickwede, M, Schütze, N & Baums, CG 2022, 'd-Alanylation of Lipoteichoic Acids in Streptococcus suis Reduces Association With Leukocytes in Porcine Blood', Frontiers in Microbiology, Jg. 13, S. 822369. https://doi.org/10.3389/fmicb.2022.822369

Palusińska-Szysz, M, Jurak, M, Gisch, N, Waldow, F, Zehethofer, N, Nehls, C, Schwudke, D, Koper, P & Mazur, A 2022, 'The human LL-37 peptide exerts antimicrobial activity against Legionella micdadei interacting with membrane phospholipids', BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, Jg. 1867, Nr. 6, S. 159138. https://doi.org/10.1016/j.bbalip.2022.159138

Stafford CA, Gassauer AM, de Oliveira Mann CC, Tanzer MC, Fessler E, Wefers B, Nagl D, Kuut G, Sulek K, Vasilopoulou C, Schwojer SJ, Wiest A, Pfautsch MK, Wurst W, Yabal M, Fröhlich T, Mann M, Gisch N, Jae LT, Hornung V, 'Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation', Nature, 2022 Aug 24. Online ahead of print. https://doi.org/10.1038/s41586-022-05125-x

 

2021

Brandenburg, J, Marwitz, S, Tazoll, SC, Waldow, F, Kalsdorf, B, Vierbuchen, T, Scholzen, T, Gross, A, Goldenbaum, S, Hölscher, A, Hein, M, Linnemann, L, Reimann, M, Kispert, A, Leitges, M, Rupp, J, Lange, C, Niemann, S, Behrends, J, Goldmann, T, Heine, H, Schaible, UE, Hölscher, C, Schwudke, D & Reiling, N 2021, 'WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis', Journal of Clinical Investigation, Jg. 131, Nr. 16, e141833. https://doi.org/10.1172/JCI141833

Gisch, N, Peters, K, Thomsen, S, Vollmer, W, Schwudke, D & Denapaite, D 2021, 'Commensal Streptococcus mitis produces two different lipoteichoic acids of type I and type IV', GLYCOBIOLOGY. https://doi.org/10.1093/glycob/cwab079

Jakob, CEM, Stecher, M, Fuhrmann, S, Wingen-Heimann, S, Heinen, S, Anton, G, Behnke, M, Behrends, U, Boeker, M, Castell, S, Demski, H, Diefenbach, M, Falgenhauer, JC, Fritzenwanker, M, Gastmeier, P, Gerhard, M, Glöckner, S, Golubovic, M, Gunsenheimer Bartmeyer, B, Ingenerf, J, Kaiser, R, Körner, M-L, Loag, W, Mchardy, A, Molitor, E, Nübel, U, Pritsch, M, Ramharter, M, Rieg, SR, Rupp, J, Schindler, D, Schwudke, D, Spinner, C, Stottmeier, B, Vehreschild, M, Willmann, M & Vehreschild, JJ 2021, 'Needs for an Integration of Specific Data Sources and Items - First Insights of a National Survey Within the German Center for Infection Research', Studies in health technology and informatics, Jg. 278, S. 237-244. https://doi.org/10.3233/SHTI210075

Köfeler, HC, Eichmann, TO, Ahrends, R, Bowden, JA, Danne-Rasche, N, Dennis, EA, Fedorova, M, Griffiths, WJ, Han, X, Hartler, J, Holčapek, M, Jirásko, R, Koelmel, JP, Ejsing, CS, Liebisch, G, Ni, Z, O'Donnell, VB, Quehenberger, O, Schwudke, D, Shevchenko, A, Wakelam, MJO, Wenk, MR, Wolrab, D & Ekroos, K 2021, 'Quality control requirements for the correct annotation of lipidomics data', Nature communications, Jg. 12, Nr. 1, S. 4771. https://doi.org/10.1038/s41467-021-24984-y

Kutschera, A, Schombel, U, Schwudke, D, Ranf, S & Gisch, N 2021, 'Analysis of the Structure and Biosynthesis of the Lipopolysaccharide Core Oligosaccharide of Pseudomonas syringae pv. tomato DC3000', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Jg. 22, Nr. 6. https://doi.org/10.3390/ijms22063250

Kyamakya, K, Haj Mosa, A, Machot, FA & Chedjou, JC 2021, 'Document-Image Related Visual Sensors and Machine Learning Techniques', Sensors, Jg. 21, Nr. 17. https://doi.org/10.3390/s21175849

Lunding, LP, Krause, D, Stichtenoth, G, Stamme, C, Lauterbach, N, Hegermann, J, Ochs, M, Schuster, B, Sedlacek, R, Saftig, P, Schwudke, D, Wegmann, M & Damme, M 2021, 'LAMP3 deficiency affects surfactant homeostasis in mice', PLoS genetics, Jg. 17, Nr. 6, S. e1009619. https://doi.org/10.1371/journal.pgen.1009619

Schreiber, T, Falk-Paulsen, M, Kuiper, J, Aden, K, Noth, R, Gisch, N, Schreiber, S, Rosenstiel, P & Bewig, B 2021, 'IL23R on myeloid cells is involved in murine pulmonary granuloma formation', EXPERIMENTAL LUNG RESEARCH, Jg. 47, Nr. 7, S. 344-353. https://doi.org/10.1080/01902148.2021.1962433

Walter, K, Kokesch-Himmelreich, J, Treu, A, Waldow, F, Hillemann, D, Jakobs, N, Lemm, A-K, Schwudke, D, Römpp, A & Hölscher, C 2021, 'Interleukin-13 overexpressing mice represent an advanced pre-clinical model for detecting the distribution of anti-mycobacterial drugs within centrally necrotizing granulomas', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, S. AAC0158821. https://doi.org/10.1128/AAC.01588-21

Huck, B , Hidalgo, A, Waldow, F, Schwudke, D, Gaede, KI, Feldmann, C, Carius, P, Autilio, C, Pérez-Gil, J, Schwarzkopf, K, Murgia, X, Loretz, B,  Lehr, CM, "Systematic Analysis of Composition, Interfacial Performance and Effects of Pulmonary Surfactant Preparations on Cellular Uptake and Cytotoxicity of Aerosolized Nanomaterials", Small Science, Volume 1, Issue 12, https://doi.org/10.1002/smsc.202100067

Buchkapitel / Book Chapter:

Knaack, W, Hölzl, G, Gisch, N 2021 'Structural Analysis of Glycosylglycerolipids Using NMR Spectroscopy', In: Plant Lipids - Methods and Protocols, /Methods Mol Biol/., Vol. 2295, S. 249-272.
https://doi.org/10.1007/978-1-0716-1362-7_14

 

2020

Al Machot, F, R Elkobaisi, M & Kyamakya, K 2020, 'Zero-Shot Human Activity Recognition Using Non-Visual Sensors', Sensors, Jg. 20, Nr. 3. https://doi.org/10.3390/s20030825

Bleuzé, M, Auger, J-P, Lavagna, A, Gisch, N, Gottschalk, M & Segura, M 2020, 'In vitro characterization of granulocyte-colony stimulating factor (G-CSF) production by dendritic cells and macrophages during Streptococcus suis infection', IMMUNOBIOLOGY, Jg. 225, Nr. 4, S. 151979. https://doi.org/10.1016/j.imbio.2020.151979

Cairns, CM, van Faassen, H, St Michael, F, Aubry, A, Henry, KA, Rossotti, MA, Logan, SM, Hussack, G, Gisch, N, Hogendorf, WFJ, Pedersen, CM & Cox, AD 2020, 'Development and Characterization of Mouse Monoclonal Antibodies Specific for Clostridiodes (Clostridium) difficile Lipoteichoic Acid', ACS Chemical Biology, Jg. 15, Nr. 4, S. 1050-1058. https://doi.org/10.1021/acschembio.0c00066

Lange, C, Aarnoutse, R, Chesov, D, van Crevel, R., Gillespie, SH, Grobbel, H-P, Kalsdorf, B, Kontsevaya, I, van Laarhoven, A, Nishiguchi, T, Mandalakas, A, Merker, M, Niemann, S, Köhler, N, Heyckendorf, J, Reimann, M, Ruhwald, M, Sanchez-Carballo, P, Schwudke, D, Waldow, F & DiNardo, AR 2020, 'Perspective for Precision Medicine for Tuberculosis', Front. Immunol., 11:566608. https://doi.org/10.3389/fimmu.2020.566608

Lavagna, A, Auger, J-P, Girardin, SE, Gisch, N, Segura, M & Gottschalk, M 2020, 'Recognition of Lipoproteins by Toll-like Receptor 2 and DNA by the AIM2 Inflammasome Is Responsible for Production of Interleukin-1β by Virulent Suilysin-negative Streptococcus suis Serotype 2', Pathogens, Jg. 9, Nr. 2. https://doi.org/10.3390/pathogens9020147

Jnoub, N, Al Machot, F & Klas, W 2020, 'A Domain-Independent Classification Model for Sentiment Analysis Using Neural Models', Applied Sciences, Jg. 10. https://doi.org/10.3390/app10186221

Peng, B, Kopczynski, D, Pratt, BS, Ejsing, CS, Burla, B, Hermansson, M, Benke, PI, Tan, SH, Chan, MY, Torta, F, Schwudke, D, Meckelmann, SW, Coman, C, Schmitz, OJ, MacLean, B, Manke, M-C, Borst, O, Wenk, MR, Hoffmann, N & Ahrends, R 2020, 'LipidCreator workbench to probe the lipidomic landscape', Nature communications, Jg. 11, Nr. 1, S. 2057. https://doi.org/10.1038/s41467-020-15960-z

Vinogradov, E, Lindner, B & Holst, O 2020, 'Structural analysis of the core and polysaccharide from the lipopolysaccharide produced by Chromobacterium violaceum strain ATCC 12472 (NCTC 9757)', CARBOHYDRATE RESEARCH, Jg. 498, S. 108182. https://doi.org/10.1016/j.carres.2020.108182

Voß, F, van Beek, LF, Schwudke, D, Ederveen, THA, van Opzeeland, FJ, Thalheim, D, Werner, S, de Jonge, MI & Hammerschmidt, S 2020, 'Lipidation of Pneumococcal Antigens Leads to Improved Immunogenicity and Protection', Vaccines, Jg. 8, Nr. 2. https://doi.org/10.3390/vaccines8020310

 

2019

Al Machot F, Elmachot A, Ali M, Al Machot E, Kyamakya K 2019 'A Deep-Learning Model for Subject-Independent Human Emotion Recognition Using Electrodermal Activity Sensors' Sensors, 19: E1659. https://doi.org/10.3390/s19071659

Azzouz D, Omarbekova A, Heguy A, Schwudke D, Gisch N, Rovin BH, Caricchio R, Buyon JP, Alekseyenko AV, Silverman GJ 2019 'Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal' Ann Rheum Dis. 78:947-956. https://doi.org/10.1136/annrheumdis-2018-214856

Correa W, Brandenburg J, Behrends J, Heinbockel L, Reiling N, Paulowski L, Schwudke D, Stephan K, Martinez-de-Tejada G, Brandenburg K, Gutsmann T 2019 'Inactivation of bacteria by γ-irradiation to investigate the interaction with antimicrobial peptides.' Biophys. J., pii: S0006-3495(19)30859-8. https://doi.org/10.1016/j.bpj.2019.10.012 [Epub ahead of print]

Komazin G, Maybin M, Woodard RW, Scior T, Schwudke D, Schombel U, Gisch N, Mamat U, Meredith TC 2019 'Substrate structure-activity relationship reveals a limited lipopolysaccharide chemotype range for intestinal alkaline phosphatase' J Biol Chem 294:19405-19423. https://doi.org/10.1074/jbc.RA119.010836

Kutschera A, Dawid C, Gisch N, Schmid C, Raasch L, Gerster T, Schäffer M, Smakowska-Luzan E, Belkhadir Y, Vlot AC, Chandler CE, Schellenberger R, Schwudke D, Ernst RK, Dorey S, Hückelhoven R, Hofmann T, Ranf S. 2019 'Bacterial medium-chain 3-hydroxy fatty acid metabolites trigger immunity in Arabidopsis plants.' Science. Jg. 364, Nr. 6436, S. 178-181. https://doi.org/10.1126/science.aau1279

Kutschera A, Schombel U, Wröbel M, Gisch N, Ranf S 2019 'Loss of wbpL disrupts O-polysaccharide synthesis and impairs virulence of plant-associated Pseudomonas strains.' Mol Plant Pathol., 20:1535-1549. https://doi.org/10.1111/mpp.12864

Lavagna A, Auger J.-P., Dumesnil A., Roy D, Girardin SE, Gisch N, Segura M, Gottschalk M 2019 'Interleukin‑1 signaling induced by Streptococcus suis serotype 2 is strain‑dependent and contributes to bacterial clearance and inflammation during systemic disease in a mouse model of infection' Vet. Res. 50:52. https://doi.org/10.1186/s13567-019-0670-y

Lipinski S, Pfeuffer S, Arnold P, Treitz C, Aden K, Ebsen H, Falk-Paulsen M, Gisch N, Fazio A, Kuiper J, Luzius A, Billmann-Born S, Schreiber S, Nuñez G, Beer HD, Strowig T, Lamkanfi M, Tholey A, Rosenstiel P 2019 'Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles.' EMBO J., 38:e101266. https://doi.org/10.15252/embj.2018101266

Ring S, Eggers L, Behrends J, Wutkowski A, Schwudke D, Kröger A, Hierweger AM, Hölscher C, Gabriel G, Schneider B. 2019 'Blocking IL-10 receptor signaling ameliorates Mycobacterium tuberculosis infection during influenza-induced exacerbation.' JCI Insight. Apr 18;5. pii: 126533. https://doi.org/10.1172/jci.insight.126533

Pfalzgraff A, Correa W, Heinbockel L, Schromm AB, Lübow C, Gisch N, Martinez-de-Tejada G, Brandenburg K, Weindl G 2019 'LPS-neutralizing peptides reduce outer membrane vesicle-induced inflammatory responses' Biochim Biophys Acta Mol Cell Biol Lipids. Jun 1. pii: S1388-1981(19)30092-7. https://doi.org/10.1016/j.bbalip.2019.05.018

 

2018

Waldow, F, Kohler, TP, Heß, N, Schwudke, D, Hammerschmidt, S & Gisch, N 2018, 'Attachment of phosphorylcholine residues to pneumococcal teichoic acids and modification of substitution patterns by the phosphorylcholine esterase' The Journal of biological chemistry. https://doi.org/10.1074/jbc.RA118.003360

Bonzón-Kulichenko, E, Moltó, E, Pintado, C, Fernández, A, Arribas, C, Schwudke, D, Gallardo, N, Shevchenko, A & Andrés, A 2018, 'Changes in visceral adipose tissue plasma membrane lipid composition in old rats are associated with adipocyte hypertrophy with aging' The journals of gerontology. Series A, Biological sciences and medical sciences, Jg. 73, Nr. 9, S. 1139-1146. https://doi.org/10.1093/gerona/gly081

Hölzl, G, Sohlenkamp, C, Vences-Guzmán, MA & Gisch, N 2018, 'Headgroup hydroxylation by OlsE occurs at the C4 position of ornithine lipid and is widespread in proteobacteria and bacteroidetes' CHEMISTRY AND PHYSICS OF LIPIDS , Jg. 213, S. 32-38. https://doi.org/10.1016/j.chemphyslip.2018.03.002

Hofmann, S, Krajewski, M, Scherer, C, Scholz, V, Mordhorst, V, Truschow, P, Schöbel, A, Reimer, R, Schwudke, D, Herker, E 2018 'Complex lipid metabolic remodeling is required for efficient hepatitis C virus replication', Biochim Biophys Acta Mol Cell Biol Lipids,  Jg. 1863, Nr. 9, S. 1041-1056. https://doi.org/10.1016/j.bbalip.2018.06.002

Müller, C, Hardt, M, Schwudke, D, Neuman, BW, Pleschka, S & Ziebuhr, J 2018, 'Inhibition of Cytosolic Phospholipase A2α Impairs an Early Step of Coronavirus Replication in Cell Culture' JOURNAL OF VIROLOGY, Jg. 92, Nr. 4. https://doi.org/10.1128/JVI.01463-17

Eggers, LF & Schwudke, D 2018, 'Shotgun Lipidomics Approach for Clinical Samples' Methods in Molecular Biology, Jg. 1730, S. 163-174. https://doi.org/10.1007/978-1-4939-7592-1_12

Wutkowski, A, Krajewski, M, Bagwan, N, Schäfer, M, Paudyal, BR, Schaible, UE & Schwudke, D 2018, 'Software-aided quality control of parallel reaction monitoring based quantitation of lipid mediators' ANALYTICA CHIMICA ACTA, Jg. 1037, S. 168-176. https://doi.org/10.1016/j.aca.2018.01.044

Gisch, N, Auger, J-P, Thomsen, S, Roy, D, Xu, J, Schwudke, D & Gottschalk, M 2018, 'Structural analysis and immunostimulatory potency of lipoteichoic acids isolated from three Streptococcus suis serotype 2 strains' The Journal of biological chemistry, Jg. 293, Nr. 31, S. 12011-12025. https://doi.org/10.1074/jbc.RA118.002174

Bülow, S, Zeller, L, Werner, M, Toelge, M, Holzinger, J, Entzian, C, Schubert, T, Waldow, F, Gisch, N, Hammerschmidt, S, Gessner, A 2018 'Bactericidal/Permeability-Increasing Protein Is an Enhancer of Bacterial Lipoprotein Recognition' FRONT. IMMUNOL., Jg. 9, Art. 2768. https://doi.org/10.3389/fimmu.2018.02768

Gonzalez, AC, Stroobants, S, Reisdorf, P, Gavin, AL, Nemazee, D, Schwudke, D, D'Hooge, R, Saftig, P, Damme, M 2018 'PLD3 and spinocerebellar ataxia' BRAIN, Jg. 141, e78. https://doi.org/10.1093/brain/awy258

Casillo, A, Ziaco, M, Lindner, B, Parrilli, E, Schwudke, D, Holgado, A, Beyaert, R, Lanzetta, R, Tutino, ML, Corsaro, MM 'Lipid A structural characterization from the LPS of the Siberian psychro-tolerant Psychrobacter arcticus 273-4 grown at low temperature' EXTREMOPHILES, Jg. 22, S. 955-963. https://doi.org/10.1007/s00792-018-1051-6

Kos, O, Alexander, C, Brandenburg, K, Chen, Z, Heini, A, Heumann, D, Khatri, I, Mach, JP, Rietschel, ET, Terskikh, A, Ulmer, AJ, Waelli, T, Yu, K, Zähringer, U, Gorczynski, RM 2018 'Regulation of fetal hemoglobin expression during hematopoietic stem cell development and its importance in bone metabolism and osteoporosis' INT IMMUNOPHARMACOL, Jg. 57, S. 112-120. https://doi.org/10.1016/j.intimp.2018.02.010

Khatri, I, Alexander, C, Brandenburg, K, Chen, Z, Heini, A, Heumann, D, Mach, JP, Mazzoli, V, Rietschel, E, Terskikh, A, Ulmer, A, Yu, K, Zähringer, U, Gorczynski, R 2018 'Analysis of cytokine immune response profile in response to inflammatory stimuli in mice with genetic defects in fetal and adult hemoglobin chain expression' PHARMACOGENOMICS J., Jg. 18, S. 546-555. https://doi.org/10.1038/s41397-017-0008-y

Michael, J, Steinberger, C, Shekhovtsov, V, Al Machot, F, Ranasinghe, S, Morak, G 2018 'The HBMS Story, Past and Future of an Active Assistance Approach' EMISAJ, Jg. 13, S. 345-370. https://doi.org/10.18417/emisa.si.hcm.26

Lunardi, GM, Al Machot, F, Shekhovtsov, VA, Maran, V, Medeiros Machado, G, Machado, A, Mayr, HC, Palazzo M. de Oliveira, J 2018 'IoT-based Human Action Prediction' INTERNET OF THINGS, Elsevier, Jg. 3/4, S. 52-68. https://doi.org/10.1016/j.iot.2018.09.007

Ali, M, Al Machot, F, Mosa, AH, Jdeed, M, Al Machot, E, Kyamakya, K 2018 'A Globally Generalized Emotion Recognition System Involving Different Physiological Signals Sensors' MDPI, Jg. 18, pii: E1905. https://doi.org/10.3390/s18061905

Lunardi, GM, Medeiros  Machado, G, Al  Machot, F, Maran, V,  Machado, A, Mayr, HC, Shekhovtsov, VA, Palazzo M. de Oliveira, J 2018 'Probabilistic Ontology Reasoning in Ambient Assistance, Predicting Human   Actions' Proceedings of 32nd International Conference on Advanced Information Networking and Applications (AINA), S. 593-600. https://doi.org/10.1109/AINA.2018.00092

Al  Machot, F, Ali, M,  Ranasinghe, S, Mosa, AH, Kyamakya, K 2018 'Improving Subject-independent Human Emotion Recognition Using Electrodermal Activity Sensors for Active and Assisted Living' Proceedings of 11th ACM International Conference on PErvasive Technologies Related to Assistive Environments (PETRA), S. 222-228. https://doi.org/10.1145/3197768.3201523

Al Machot, F, Ranasinghe, S, Plattner, J, Jnoub, N 2018 'Human Activity  Recognition  based  on  Real  Life Scenarios' CoMoRea 2018, IEEE International Conference on Pervasive Computing and Communications (PERCOM), S. 3-8. https://doi.org/10.1109/PERCOMW.2018.8480138

 

Buchkapitel:

Recent Advances in Nonlinear Dynamics and Synchronization (Springer, 2018)

Ali, M,  Mosa, AH, Al  Machot, F, Kyamakya, K 'Emotion Recognition Involving Physiological and Speech Signals:  A Comprehensive Review' S. 287-302. https://doi.org/10.1007/978-3-319-58996-1_13

Al Machot, F, Mayr, HC, Ranasinghe, S 'A Hybrid Reasoning Approach for Activity Recognition based on Answer Set Programming and Dempster-Shafer Theory', S. 303-318. https://doi.org/10.1007/978-3-319-58996-1_14

 

2017

Al Machot, F, Haj Mosa, A, Ali, M & Kyamakya, K 2017, 'Activity Recognition in Sensor Data Streams for Active and Assisted Living Environments' IEEE Transactions on Circuits and Systems for Video Technology, Bd PP, Nr. 99. https://doi.org/10.1109/tcsvT.2017.2764

Ausgezeichnet als "Paper of the month" der DGHM (01/2018)
Heß N, Waldow F, Kohler TP, Rohde M, Kreikemeyer B, Gómez-Mejia A, Hain T, Schwudke D, Vollmer W, Hammerschmidt S, Gisch N. Lipoteichoic acid deficiency permits normal growth but impairs virulence of Streptococcus pneumoniae. Nat Commun. 2017 Dec 12; 8: 2093. https://doi.org/10.1038/s41467-017-01720-z

Hebbar S, Khandelwal A, R J, Hindle SJ, Chiang YN, Yew JY, Sweeney ST, Schwudke D. Lipid metabolic perturbation is an early-onset phenotype in adult spin mutants: a Drosophila model for lysosomal storage disorders. Mol Biol Cell. 2017 Oct 18. pii: mbc.E16-09-0674. https://doi.org/10.1091/mbc.E16-09-0674 [Epub ahead of print]

Schwudke D, Shevchenko A, Hoffmann N, Ahrends R. Lipidomics informatics for life-science. J Biotechnol. 2017 Aug 16. pii: S0168-1656(17)31596-1. https://doi.org/10.1016/j.jbiotec.2017.08.010 [Epub ahead of print]

Eggers LF, Müller J, Marella C, Scholz V, Watz H, Kugler C, Rabe KF, Goldmann T, Schwudke D. Lipidomes of lung cancer and tumour-free lung tissues reveal distinct molecular signatures for cancer differentiation, age, inflammation, and pulmonary emphysema. Sci Rep. 2017 Sep 11;7(1):11087. https://doi.org/10.1038/s41598-017-11339-1

Di Guilmi AM, Bonnet J, Peiβert S, Durmort C, Gallet B, Vernet T, Gisch N, Wong YS. Specific and spatial labeling of choline-containing teichoic acids in Streptococcus pneumoniae by click chemistry. Chem Commun (Camb). 2017 Sep 21;53(76):10572-10575. https://doi.org/10.1039/c7cc05646j

Corsaro, MM, Casillo, A, Ziaco, M, Lindner, B, Parrilli, E, Schwudke, D, Holgado, A, Verstrepen, L, Sannino, F, Beyaert, R, Lanzetta, R, Tutino, ML. Unusual Lipid A from a cold adapted bacterium: detailed structural characterization. Chembiochem. 2017 Jun 26. https://doi.org/10.1002/cbic.201700287 [Epub ahead of print]

Mehlitz, A, Eylert, E, Huber, C, Lindner, B, Vollmuth, N, Karunakaran, K, Goebel, W, Eisenreich, W, Rudel, T. Metabolic adaptation of Chlamydia trachomatis to mammalian host cells. Mol Microbiol. 2017 Mar;103(6):1004-1019. https://doi.org/10.1111/mmi.13603 Epub 2017 Jan 31.

Gorczynski, RM, Alexander, C, Brandenburg, K, Chen, Z, Heini, A, Neumann, D, Mach, JP, Rietschel, ET, Tersikh, A, Ulmer, AJ, Yu, K, Zähringer, U, Khatri, I. An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression. Int Immunopharmacol. 2017 Jun 19;50:69-76. https://doi.org/10.1016/j.intimp.2017.06.003 [Epub ahead of print]

Steffens, T, Duda, K, Lindner, B, Vorhölter, F-J, Bednarz, H, Niehaus, K & Holst, O 2017, 'The lipopolysaccharide of the crop pathogen Xanthomonas translucens pv. translucens: chemical characterization and determination of signaling events in plant cells' GLYCOBIOLOGY, Bd 27, Nr. 3, S. 264-274. https://doi.org/10.1093/glycob/cww093

Hindle, SJ, Hebbar, S, Schwudke, D, Elliott, CJ & Sweeney, ST 2017, 'A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline' Neurobiology of disease, Nr. 98, S. 77-87. https://doi.org/10.1016/j.nbd.2016.11.012

Sezin, T, Krajewski, M, Wutkowski, A, Mousavi, S, Chakievska, L, Bieber, K, Ludwig, RJ, Dahlke, M, Rades, D, Schulze, FS, Schmidt, E, Kalies, K, Gupta, Y, Schilf, P, Ibrahim, SM, König, P, Schwudke, D, Zillikens, D & Sadik, CD 2017, 'The Leukotriene B4 and Its Receptor BLT1 Act as Critical Drivers of Neutrophil Recruitment in Murine Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita' Journal of Investigative Dermatology. https://doi.org/10.1016/j.jid.2016.12.021

Jeschke, A, Zehethofer, N, Schwudke, D & Haas, A 2017, 'Quantification of Phosphatidylinositol Phosphate Species in Purified Membranes' Methods in Enzymology, Bd 587, S. 271-291. https://doi.org/10.1016/bs.mie.2016.10.037

Casillo, A, Ziaco, M, Lindner, B, Merino, S, Mendoza-Barberá, E, Tomás, JM & Corsaro, MM 2017, 'Structural Characterization of Core Region in Erwinia amylovora Lipopolysaccharide' INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Bd 18, Nr. 3. https://doi.org/10.3390/ijms18030559

 

2016

Wohnig S, Spork AP, Koppermann S, Mieskes G, Gisch N, Jahn R, Ducho C. Total Synthesis of Dansylated Park's Nucleotide for High-Throughput MraY Assays. Chemistry. 2016 Dec 5;22(49):17813-17819. https://doi.org/10.1002/chem.201604279 Epub 2016 Oct 28.

Carillo S, Pieretti G, Casillo A, Lindner B, Romano I, Nicolaus B, Parrilli M, Giuliano M, Cammarota M, Lanzetta R, Corsaro MM. Structural characterization of the lipid A from the LPS of the haloalkaliphilic bacterium Halomonas pantelleriensis. Extremophiles. 2016 Sep;20(5):687-94.

Klein G, Stupak A, Biernacka D, Wojtkiewicz P, Lindner B, Raina S. Multiple transcriptional factors regulate transcription of the rpoE gene in Escherichia coli under different growth conditions and when the lipopolysaccharide biosynthesis is defective. J Biol Chem. 2016 Sep 14. pii: jbc.M116.748954. [Epub ahead of print]

Palusińska-Szysz, A. Zdybicka-Barabas, E. Reszczyńska, R. Luchowski, M. Kania, N. Gisch, F. Waldow, P. Mak, W. Danikiewicz, W. I. Gruszecki, M. Cytryńska. The lipid composition of Legionella dumoffii membrane modulates the interaction with Galleria mellonella apolipophorin III. Biochim Biophys Acta. 2016 Jul;1861(7):617-29. https://doi.org/10.1016/j.bbalip.2016.04.011 Epub 2016 Apr 17.

Brandenburg, K, Heinbockel, L, Correa-Vargas, W, Fukuoka, S, Gutsmann, T, Zähringer, U & Koch, MHJ 2016, 'Supramolecular structure of enterobacterial wild-type lipopolysaccharides (LPS), fractions thereof, and their neutralization by Pep19-2.5' Journal of Structural Biology., https://doi.org/10.1016/j.jsb.2016.01.014

 

Buchkapitel:

Encyclopedia of Lipidomics (Springer, 2016)
Lars F. Eggers, Dominik Schwudke; Liquid Extraction: Folch
https://doi.org/10.1007/978-94-007-7864-1_89-1

Annika Sündermann, Lars F. Eggers, Dominik Schwudke; Liquid Extraction: Bligh and Dyer
https://doi.org/10.1007/978-94-007-7864-1_88-1

Lars F. Eggers, Dominik Schwudke; Lipid Extraction: Basics of the Methyl-tert-Butyl Ether Extraction
https://doi.org/10.1007/978-94-007-7864-1_96-1

Knaack, W, Hölzl, G, Gisch, N 2021 'Structural Analysis of Glycosylglycerolipids Using NMR Spectroscopy', In: Plant Lipids - Methods and Protocols, /Methods Mol Biol/., Vol. 2295, S. 249-272.
https://doi.org/10.1007/978-1-0716-1362-7_14

 

2015

F. Renzi, U. Zähringer, C. E. Chandler, R. K. Ernst, G. R. Cornelis, S. J. Ittig. Modification of the 1-Phosphate Group during Biosynthesis of Capnocytophaga canimorsus Lipid A. Infect Immun. 2015 Dec 7;84(2):550-61. https://doi.org/10.1128/IAI.01006-15. PMID: 26644381

Hebbar, S, Sahoo, I, Matysik, A, Argudo Garcia, I, Osborne, KA, Papan, C, Torta, F, Narayanaswamy, P, Fun, XH, Wenk, MR, Shevchenko, A, Schwudke, D, Kraut, R. Ceramides And Stress Signalling Intersect With Autophagic Defects In Neurodegenerative Drosophila blue cheese (bchs) Mutants. Sci Rep. 2015 Dec 7;5:15926. https://doi.org/10.1038/srep15926

Gisch, N, Schwudke, D, Thomsen, S, Heß, N, Hakenbeck, R, Denapaite, D. Lipoteichoic acid of Streptococcus oralis Uo5: a novel biochemical structure comprising an unusual phosphorylcholine substitution pattern compared to Streptococcus pneumoniae. Sci Rep. 2015 Nov 18;5:16718. https://doi.org/10.1038/srep16718

Marella, C, Torda, AE, Schwudke, D. The LUX Score: A Metric for Lipidome Homology. PLoS Comput Biol 2015, 11(9): e1004511. https://doi.org/10.1371/journal.pcbi.1004511

de Tejada, GM, Heinbockel, L, Ferrer-Espada, R, Heine, H, Alexander, C, Bárcena-Varela, S, Goldmann, T, Correa, W,  Wiesmüller, K-H, Gisch, N, Sánchez-Gómez, S, Fukuoka, S, Schürholz, T, Gutsmann, T, Brandenburg, K. Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides. Scientific Reports 5, Article number: 14292 (2015). https://doi.org/10.1038/srep14292

Leidinger P, Treptow J, Hagens K, Eich J, Zehethofer N, Schwudke D, Oehlmann W, Lünsdorf H, Goldmann O, Schaible UE, Dittmar KE, Feldmann C. Isoniazid@Fe2O3 Nanocontainers and Their Antibacterial Effect on Tuberculosis Mycobacteria. Angew Chem Int Ed Engl. 2015 Aug 31. https://doi.org/10.1002/anie.201505493 [Epub ahead of print]

Casillo A, Parrilli E, Filomena S, Lindner B, Lanzetta R, Parrilli M, Tutino ML, Corsaro MM. Structural Investigation of the Oligosaccharide Portion Isolated from the Lipooligosaccharide of the Permafrost Psychrophile Psychrobacter arcticus 273-4. Mar Drugs. 2015 Jul 22;13(7):4539-55.

Petersen A, Kull S, Rennert S, Becker WM, Krause S, Ernst M, Gutsmann T, Bauer J, Lindner B, Jappe U. Peanut defensins: Novel allergens isolated from lipophilic peanut extract. J Allergy Clin Immunol. 2015 May 30. pii: S0091-6749(15)00570-9. [Epub ahead of print]

Jeschke, A, Zehethofer, N, Lindner, B, Krupp, J, Schwudke, D, Haneburger, I, Jovic, M, Backer, JM, Balla, T, Hilbi, H & Haas, A 2015, 'Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis' PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Bd 112, Nr. 15, S. 4636-41.

Zehethofer, N, Bermbach, S, Hagner, S, Garn, H, Müller, J, Goldmann, T, Lindner, B, Schwudke, D & König, P 2015, 'Lipid Analysis of Airway Epithelial Cells for Studying Respiratory Diseases' Chromatographia, Bd 78, Nr. 5-6, S. 403-413., https://doi.org/10.1007/s10337-014-2787-5

Ranf, S, Gisch, N, Schäffer, M, Illig, T, Westphal, L, Knirel, YA, Sánchez-Carballo, PM, Zähringer, U, Hückelhoven, R, Lee, J & Scheel, D 2015, 'A lectin S-domain receptor kinase mediates lipopolysaccharide sensing in Arabidopsis thaliana' NATURE IMMUNOLOGY , Bd 16, Nr. 4, S. 426-33.

Diercks, H, Semeniuk, A, Gisch, N, Hermann, M, Duda, KA & Hölzl, G 2015, 'Accumulation of novel Glycolipids and Ornithine Lipids in Mesorhizobium loti under Phosphate Deprivation' JOURNAL OF BACTERIOLOGY, Bd 197, Nr. 3, S. 497-509.

Johnston, C, Bootsma, HJ, Aldridge, C, Manuse, S, Gisch, N, Schwudke, D, Hermans, PWM, Grangeasse, C, Polard, P, Vollmer, W & Claverys, J-P 2015, 'Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology' PLOS ONE, Bd 10, Nr. 4, S. e0123702.

Mamat, U, Wilke, K, Bramhill, D, Schromm, AB, Lindner, B, Kohl, TA, Corchero, JL, Villaverde, A, Schaffer, L, Head, SR, Souvignier, C, Meredith, TC & Woodard, RW 2015, 'Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins' Microbial Cell Factories, Bd 14, S. 57.

Kallsen, K, Zehethofer, N, Abdelsadik, A, Lindner, B, Kabesch, M, Heine, H & Roeder, T 2015, 'ORMDL deregulation increases stress responses and modulates repair pathways in Drosophila airways' The Journal of allergy and clinical immunology 2015 May 12, pii: S0091-6749(15)00549-7. https://doi.org/10.1016/j.jaci.2015.04.009

 

Buchkapitel:

Gisch, N., Peters, K., Zähringer, U. & Vollmer, W. The pneumococcal cell wall. In: Streptococcus pneumoniae: Molecular mechanisms of host-pathogen interactions (eds J. S. Brown, S. Hammerschmidt, & C. J. Orihuela) Chapter 8, 145-167 (Elsevier, 2015).

 

2014

Gronbach, K, Flade, I, Holst, O, Lindner, B, Ruscheweyh, HJ, Wittmann, A, Menz, S, Schwiertz, A, Adam, P, Stecher, B, Josenhans, C, Suerbaum, S, Gruber, AD, Kulik, A, Huson, D, Autenrieth, IB & Frick, J-S. Endotoxicity of lipopolysaccharide as a determinant of T-cell-mediated colitis induction in mice. Gastroenterology 2014, 146 (3), 765-775.

Correa, W, Manrique-Moreno, M, Behrends, J, Patiño, E, Chakravarty, M, Peláez-Jaramillo, C, Garidel, P, Gutsmann, T, Brandenburg, K & Heinbockel, L.  Galleria mellonella native and analogue peptides Gm1 and ΔGm1. II) anti-bacterial and anti-endotoxic effects. Biochimica et Biophysica Acta 2014, 1838 (10), 2739-2744.

Hilmi D, Parcina M, Stollewerk D, Ostrop J, Josten M, Meilaender A, Zaehringer U, Wichelhaus TA, Bierbaum G, Heeg K, Wolz C, Bekeredjian-Ding I. Heterogeneity of host TLR2 stimulation by Staphylocoocus aureus isolates. PLoS One. 2014 May 8;9(5):e96416. https://doi.org/10.1371/journal.pone.0096416 eCollection 2014.

Claes AK, Steck N, Schultz D, Zähringer U, Lipinski S, Rosenstiel P, Geddes K, Philpott DJ, Heine H, Grassl GA. Salmonella enterica serovar Typhimurium ΔmsbB Triggers Exacerbated Inflammation in Nod2 Deficient Mice. PLoS One. 2014 Nov 25;9(11):e113645. https://doi.org/10.1371/journal.pone.0113645

Silipo A, Vitiello G, Gully D, Sturiale L, Chaintreuil C, Fardoux J, Gargani D, Lee HI, Kulkarni G, Busset N, Marchetti R, Palmigiano A, Moll H, Engel R, Lanzetta R, Paduano L, Parrilli M, Chang WS, Holst O, Newman DK, Garozzo D, D'Errico G, Giraud E, Molinaro A. Covalently linked hopanoid-lipid A improves outer-membrane resistance of a Bradyrhizobium symbiont of legumes. Nat Commun. 2014 Oct 30;5:5106. https://doi.org/10.1038/ncomms6106

Komaniecka I, Choma A, Mazur A, Duda KA, Lindner B, Schwudke D, Holst O. Occurrence of an unusual hopanoid-containing lipid A among lipopolysaccharides from Bradyrhizobium species. J Biol Chem. 2014 Dec 19;289(51):35644-55. https://doi.org/10.1074/jbc.M114.614529 Epub 2014 Nov 3.

Vassal-Stermann E, Lacroix M, Gout E, Laffly E, Pedersen CM, Martin L, Amoroso A, Schmidt RR, Zähringer U, Gaboriaud C, Di Guilmi AM, Thielens NM. Human L-Ficolin Recognizes Phosphocholine Moieties of Pneumococcal Teichoic Acid. J Immunol. 2014 Dec 1; 193(11):5699-708. https://doi.org/10.4049/jimmunol.14001127 Epub Oct 2014.

Hogendorf WFJ, Gisch N, Schwudke D, Heine H, Bols M, Pedersen CM, Total Synthesis of Five Lipoteichoic acids of Clostridium difficile, Chemistry - A European Journal. 2014 20(42): 13511-13516.

Böcking C, Harb H, Ege MJ, Zehethofer N, Fischer K, Krauß J, Holst O, Nüsing RM, Lindner B, von Mutius E, Renz H, Garn H, Pfefferle PI. Bioavailability and allergoprotective capacity of milk-associated conjugated linoleic acid in a murine model of allergic airway inflammation. Int Arch Allergy Immunol. 2014;163(3):234-42. https://doi.org/10.1159/000358523

Zähringer U, Ittig S, Lindner B, Moll H, Schombel U, Gisch N, Cornelis GR. NMR Based Structural Analysis of the Complete Rough-type LPS Isolated From Capnocytophaga canimorsus. J Biol Chem. 2014 289(34): 23963-23976.

Abdullah MR, Gutiérrez-Fernández J, Pribyl T, Gisch N, Saleh M, Rohde M, Petruschka L, Burchhardt G, Schwudke D, Hermoso JA, Hammerschmidt S. Structure of the pneumococcal l,d-carboxypeptidase DacB and pathophysiological effects of disabled cell wall hydrolases DacA and DacB. Mol Microbiol. 2014 93(6): 1183–1206.

Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Roa Rosales A, Molinaro A, Moynagh PN, Lajoie G, Valvano MA. Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune response. J Biol Chem. 2014 Jul 4;289(27):19231-44. https://doi.org/10.1074/jbc.M114.562603. Epub 2014 May 19.

Hebbar S, Schulz WD, Sauer U, Schwudke D. Laser Capture Microdissection coupled with on-column extraction LC-MS(n) enables lipidomics of fluorescently labeled Drosophila neurons. Anal  Chem 2014 Junn 3; 86(11):5345-52. https://doi.org/10.1021/ac500276r. PMID:24820458

Turska-Szewczuk A, Duda KA, Schwudke D, Pekala A, Kozinska A, Holst O. Structural studies of the lipopolysaccharide from the fish pathogen Aeromonas veronii strain Bs19, serotype O16. Mar Drugs. 2014 Mar 7;12(3):1298-316. https://doi.org/10.3390/md12031298

Kohler T, Gisch N, Binsker U, Schlag M, Darm K, Völker U, Zähringer U & Hammerschmidt S. Repeating structures of the major staphylococcal autolysin are essential for the interaction with human thrombospondin-1 and vitronectin.
J Biol Chem 2014 Feb 14; 289(7):4070-82.

 

2013

Zähringer U, Kawahara K, & Kosma P. 2013. ‘Isolation and structural characterization of a (Kdo-isosteric) D-glycero-alpha-D-talo-oct-2-ulopyranosidic acid (Ko) interlinking the lipid A and core oligosaccharide in the lipopolysaccharide of Acinetobacter calcoaceticus NCTC 10305’. Carbohydr Res. Bd. 378: S. 63-70.
 
Scior T, Lozano-Aponte J, Figueroa-Vazquez V, Yunes-Rojas JA, Zähringer U & Alexander C. 2013. ‘Three-dimensional mapping of differential amino acids of human, murine, canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A,  Antagonism by eritoran and species-dependent activities of lipid IVA in the mammalian LPS sensor system’. Comp Struct Biotechnol  J. 7 (9), p. 1-11 (online article).

Scior, T, Alexander, C & Zähringer, U. 2013. 'Reviewing and identifying amino acids of human, murine, canine and equine TLR4 / MD-2 receptor complexes conferring endotoxic innate immunity activation by LPS/lipid A, or antagonistic effects by Eritoran'. Comp Struct Biotechnol  J. 5 (6), p. 1-13 (online article).

Gronbach, K, Flade, I, Holst, O, Lindner, B, Ruscheweyh, HJ, Wittmann, A, Menz, S, Schwiertz, A, Adam, P, Stecher, B, Josenhans, C, Suerbaum, S, Gruber, A, Kulik, A, Huson, D, Autenrieth, I & Frick, J-S 2013, 'Endotoxicity of Lipopolysaccharide as a determinant of T-cell mediated colitis induction in mice' Gastroenterology, Nr. https://doi.org/10.1053/j.gastro. 2013.11.033[Epub ahead of print].

Popovic, M, Andjelkovic, U, Burazer, L, Lindner, B, Petersen, A & Gavrovic-Jankulovic, M 2013, 'Biochemical and immunological characterization of a recombinantly-produced antifungal cysteine proteinase inhibitor from green kiwifruit (Actinidia deliciosa)' Phytochemistry. Bd. 94. S. 53-59. https://doi.org/10.1016/j.phytochem.2013.06.006. Epub 2013 Jul 3.

Posch, G, Andrukhov, O, Vinogradov, E, Lindner, B, Messner, P, Holst, O & Schäffer, C 2013, 'Structure and immunogenicity of the rough-type lipopolysaccharide from the periodontal pathogen Tannerella forsythia' Clinical and Vaccine Immunology : CVI, Bd 20, Nr. 6, S. 945-53., https://dx.doi.org/10.1128/CVI.00139-13

Turska-Szewczuk, A, Lindner, B, Komaniecka, I, Kozinska, A, Pekala, A, Choma, A & Holst, O 2013, 'Structural and immunochemical studies of the lipopolysaccharide from the fish pathogen, Aeromonas bestiarum strain K296, serotype O18'. Marine drugs, Bd 11, Nr. 4, S. 1235-55., https://dx.doi.org/10.3390/md11041235

Carillo, S, Pieretti, G, Lindner, B, Romano, I, Nicolaus, B, Lanzetta, R, Parrilli, M & Corsaro, MM 2013, 'Structural characterization of the core oligosaccharide isolated from the lipopolysaccharide of the haloalkaliphilic bacterium Salinivibrio sharmensis strain BAG(T)' Carbohydrate Research, Bd 368, S. 61-7., https://dx.doi.org/10.1016/j.carres.2012.12.013

Sydor, T, von Bargen, K, Hsu, F-F, Huth, G, Holst, O, Wohlmann, J, Becken, U, Dykstra, T, Söhl, K, Lindner, B, Prescott, JF, Schaible, UE, Utermöhlen, O & Haas, A 2013, 'Diversion of phagosome trafficking by pathogenic Rhodococcus equi depends on mycolic acid chain length' Cellular Microbiology, Bd 15, Nr. 3, S. 458-473., https://dx.doi.org/10.1111/cmi.12050

Pupo, E, Lindner, B, Brade, H & Schromm, AB 2013, 'Intact rough- and smooth-form lipopolysaccharides from Escherichia coli separated by preparative gel electrophoresis exhibit differential biological activity in human macrophages' FEBS Journal, Bd 280, Nr. 4, S. 1095-1111., https://dx.doi.org/10.1111/febs.12104

Carillo, S, Pieretti, G, Lindner, B, Romano, I, Nicolaus, B, Lanzetta, R, Parrilli, M & Corsaro, MM 2013, 'The lipid A from the haloalkaliphilic bacterium Salinivibrio sharmensis strain BAG(T)' Marine drugs, Bd 11, Nr. 1, S. 184-93., https://dx.doi.org/10.3390/md11010184

Klein, G, Müller-Loennies, S, Lindner, B, Kobylak, N, Brade, H & Raina, S. 2013, 'Molecular and structural basis of inner core lipopolysaccharide alterations in Escherichia coli: incorporation of glucuronic acid and phosphoethanolamine in the heptose region' The Journal of Biological Chemistry, Bd 288, S. 8111-8127., https://dx.doi.org/10.1074/jbc.M112.445981

Herzog R, Schwudke D, Shevchenko A. LipidXplorer: Software for Quantitative Shotgun Lipidomics Compatible with Multiple Mass Spectrometry Platforms. CURRENT PROTOCOLS in BIOINFORMATICS 2013 14.12.1–14.12.30.

Sanderson JP, Brennan PJ, Mansour S, Matulis G, Patel O, Lissin N, Kawahara K, Zähringer U, Rossjohn J, Brenner MB, Gadola SD. CD1d protein structure determines species-selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells. EUROPEAN JOURNAL of  IMMUNOLOGY 2013; 43:815-825.
   
Gisch N, Kohler T, Ulmer AJ, Müthing J, Pribyl T, Fischer K, Lindner G, Hammerschmidt S, Zähringer U. Structural reevaluation of Streptococcus pneumoniae lipoteichoic acid and new insights into its immunostimulatory potency. JOURNAL BIOLOGICAL CHEMISTRY 2013; 288: 15654-1567.               

Gasulla F, Vom Dorp K, Dombrink I, Zähringer U, Gisch N, Bartels D. The role of lipid metabolism in the acquisition of desiccation-tolerance in Craterostigma plantagineum: a comparative approach. PLANT JOURNAL 2013 May 15. https://doi.org/10.1111/tpj.12241 [Epub ahead of print]

Subramanian M, Metya SK, Sadaf S, Kumar S, Schwudke D, Hasan G. Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia. DISEASE MODEL & MECHANISMS 2013 May;6(3):734-44.