Priority Research Area Infections
Evolution of the Resistome
Mission
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Publications
2022
Bateson, A, Ortiz Canseco, J, McHugh, TD, Witney, AA, Feuerriegel, S, Merker, M, Kohl, TA, Utpatel, C, Niemann, S, Andres, S, Kranzer, K, Maurer, FP, Ghodousi, A, Borroni, E, Cirillo, DM, Wijkander, M, Toro, JC, Groenheit, R, Werngren, J, Machado, D, Viveiros, M, Warren, RM, Sirgel, F, Dippenaar, A, Köser, CU, Sun, E & Timm, J 2022, 'Ancient and recent differences in the intrinsic susceptibility of Mycobacterium tuberculosis complex to pretomanid', JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, Jg. 77, Nr. 6, S. 1685-1693. https://doi.org/10.1093/jac/dkac070
Belheouane, M, Hermes, BM, Van Beek, N, Benoit, S, Bernard, P, Drenovska, K, Gerdes, S, Gläser, R, Goebeler, M, Günther, C, von Georg, A, Hammers, CM, Holtsche, MM, Homey, B, Horváth, ON, Hübner, F, Linnemann, B, Joly, P, Márton, D, Patsatsi, A, Pföhler, C, Sárdy, M, Huilaja, L, Vassileva, S, Zillikens, D, Ibrahim, S, Sadik, CD, Schmidt, E & Baines, JF 2022, 'Characterization of the skin microbiota in bullous pemphigoid patients and controls reveals novel microbial indicators of disease', Journal of advanced research. https://doi.org/10.1016/j.jare.2022.03.019
Chesov, E, Chesov, D, Maurer, FP, Andres, S, Utpatel, C, Barilar, I, Donica, A, Reimann, M, Niemann, S, Lange, C, Crudu, V, Heyckendorf, J & Merker, M 2022, 'Emergence of bedaquiline resistance in a high tuberculosis burden country', The European respiratory journal, Jg. 59, Nr. 3, 2100621. https://doi.org/10.1183/13993003.00621-2021
Diricks, M, Kohl, TA, Käding, N, Leshchinskiy, V, Hauswaldt, S, Jiménez Vázquez, O, Utpatel, C, Niemann, S, Rupp, J & Merker, M 2022, 'Whole genome sequencing-based classification of human-related Haemophilus species and detection of antimicrobial resistance genes', Genome medicine, Jg. 14, Nr. 1, S. 13. https://doi.org/10.1186/s13073-022-01017-x
Diricks, M, Kohl, TA, Käding, N, Leshchinskiy, V, Hauswaldt, S, Vázquez, OJ, Utpatel, C, Niemann, S, Rupp, J & Merker, M 2022, 'Correction to:Whole genome sequencing-based classifcation of human-related Haemophilus species and detection of antimicrobial resistance genes', Genome medicine, Jg. 14, Nr. 1, S. 22. https://doi.org/10.1186/s13073-022-01028-8
Kerubo, G, Ndungu, P, Shuaib, YA, Amukoye, E, Revathi, G, Homolka, S, Kariuki, S, Merker, M & Niemann, S 2022, 'Molecular Epidemiology of Mycobacterium tuberculosis Complex Strains in Urban and Slum Settings of Nairobi, Kenya', Genes, Jg. 13, Nr. 3, 475. https://doi.org/10.3390/genes13030475
Mbelele, PM, Utpatel, C, Sauli, E, Mpolya, EA, Mutayoba, BK, Barilar, I, Dreyer, V, Merker, M, Sariko, ML, Swema, BM, Mmbaga, BT, Gratz, J, Addo, KK, Pletschette, M, Niemann, S, Houpt, ER, Mpagama, SG & Heysell, SK 2022, 'Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania', JAC-antimicrobial resistance, Jg. 4, Nr. 2, S. dlac042. https://doi.org/10.1093/jacamr/dlac042
Antimycobacterial Susceptibility Testing Group 2022, 'Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment', The European respiratory journal, Jg. 59, Nr. 4, 2200166. https://doi.org/10.1183/13993003.00166-2022
2021
Chesov, E, Chesov, D, Maurer, FP, Andres, S, Utpatel, C, Barilar, I, Donica, A, Reimann, M, Niemann, S, Lange, C, Crudu, V, Heyckendorf, J & Merker, M 2021, 'Emergence of bedaquiline-resistance in a high-burden country of tuberculosis', The European respiratory journal. https://doi.org/10.1183/13993003.00621-2021
Grobbel, H-P, Merker, M, Köhler, N, Andres, S, Hoffmann, H, Heyckendorf, J, Reimann, M, Barilar, I, Dreyer, V, Hillemann, D, Kalsdorf, B, Kohl, TA, Sanchez-Carballo, P, Schaub, D, Todt, K, Utpatel, C, Maurer, FP, Lange, C & Niemann, S 2021, 'Design of multidrug-resistant tuberculosis treatment regimens based on DNA sequencing', CLINICAL INFECTIOUS DISEASES , Jg. 73, Nr. 7, S. 1194-1202. https://doi.org/10.1093/cid/ciab359
Kontsevaya, I, Lange, C, Comella-Del-Barrio, P, Coarfa, C, DiNardo, AR, Gillespie, SH, Hauptmann, M, Leschczyk, C, Mandalakas, AM, Martinecz, A, Merker, M, Niemann, S, Reimann, M, Rzhepishevska, O, Schaible, UE, Scheu, KM, Schurr, E, Abel Zur Wiesch, P & Heyckendorf, J 2021, 'Perspectives for systems biology in the management of tuberculosis', European Respiratory Review, Jg. 30, Nr. 160. https://doi.org/10.1183/16000617.0377-2020
Merker, M, Egbe, NF, Ngangue, YR, Vuchas, C, Kohl, TA, Dreyer, V, Kuaban, C, Noeske, J, Niemann, S & Sander, MS 2021, 'Transmission patterns of rifampicin resistant Mycobacterium tuberculosis complex strains in Cameroon: a genomic epidemiological study', BMC INFECTIOUS DISEASES , Jg. 21, Nr. 1, S. 891. https://doi.org/10.1186/s12879-021-06593-8
Nadarajan, D, Hillemann, D, Kamara, R, Foray, L, Conteh, OS, Merker, M, Niemann, S, Lau, J, Njoya, M, Kranzer, K, Somoskovi, A & Maurer, FP 2021, 'Evaluation of the Roche cobas MTB and MTB-RIF/INH assays in samples from Germany and Sierra Leone', JOURNAL OF CLINICAL MICROBIOLOGY, Jg. 59, Nr. 5. https://doi.org/10.1128/JCM.02983-20
Peker, N, Schuele, L, Kok, N, Terrazos, M, Neuenschwander, SM, de Beer, J, Akkerman, O, Peter, S, Ramette, A, Merker, M, Niemann, S, Couto, N, Sinha, B & Rossen, JW 2021, 'Evaluation of whole-genome sequence data analysis approaches for short- and long-read sequencing of Mycobacterium tuberculosis', Microbial genomics, Jg. 7, Nr. 11. https://doi.org/10.1099/mgen.0.000695
Sonnenkalb, L, Strohe, G, Dreyer, V, Andres, S, Hillemann, D, Maurer, FP, Niemann, S & Merker, M 2021, 'Microevolution of Mycobacterium tuberculosis Subpopulations and Heteroresistance in a Patient Receiving 27 Years of Tuberculosis Treatment in Germany', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 65, Nr. 7, S. e0252020. https://doi.org/10.1128/AAC.02520-20