Priority Research Area Infections

Host ­Determinants in Lung Infections

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Dr. Bianca Schneider
Dr. Bianca Schneider
04537 / 188-5950
04537 / 188-4190
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Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) is one of the most deadly infectious diseases worldwide. The rate of progression to disease is driven by a complex interplay of pathogen and host-related factors. The current poor understanding of protective versus non-protective host responses hampers the development of new treatments, particularly those based on immunomodulatory strategies. The overall goal of our research is to understand how host-related factors regulate anti-tuberculosis defenses, focusing on two major aspects, which are likely to play a crucial role in the pathogenesis of TB: the biological sex and viral coinfections.