Core Group

2023 

North and East African mitochondrial genetic variation needs further characterization towards precision medicine.
A. Fähnrich*, I. Stephan*, M. Hirose, F. Haarich, M.A. Awadelkareem, S. Ibrahim, H. Busch*, Wohlers I*. J Adv Res. 2023:S2090-1232(23)00034-6. doi: https://doi.org/10.1016/j.jare.2023.01.021

Editorial: Long-read sequencing-Pitfalls, benefits and success stories.
I. Wohlers, S. Garg, J.Y. Hehir-Kwa. Front Genet. 2023;13:1114542. doi: https://doi.org/10.3389/fgene.2022.1114542

 

2022

R. Saurabh, C. Fouodo, I. König, H. Busch and I. Wohlers.
A survey of genome-wide association studies (GWAS), polygenic scores (PGS) and UK Biobank (UKB) highlights resources for autoimmune disease genetics.
Front. Immunol. 2022;5;13:972107. doi: https://doi.org/10.3389/fimmu.2022.972107

H. R. Gouda, I. M. Talaat, A. Bouzid, H. El Assi, A. Nabil, T. Venkatachalam, P. Bhamidimarri, I. Wohlers, A. Mahdami, S. El-Gendi, A. Elkoraie, H. Busch, M. M. Saber-Ayad, R. Hamoudi, N. Baddour.
Genetic Analysis of CFH and MCP in Egyptian Patients with Immune-Complex Proliferative Glomerulonephritis.
Front Immunol. 2022;13:960068. doi: https://doi.org/10.3389/fimmu.2022.960068

T. Lüth, J. Laβ, S. Schaake, I. Wohlers, J. Pozojevic, R. D. Jamora, R. L. Rosales, N. Brüggemann, G. Saranza, C. C. E. Diesta, K. Schlüter, R. Tse, C. J. Reyes, M. Brand, H. Busch, C. Klein, A. Westenberger, J. Trinh.
Elucidating hexanucleotide repeat number and methylation within the X-linked dystonia-parkinsonism (XDP)-related SVA retrotransposon in TAF1 with Nanopore sequencing.
Genes (Basel). 2022;13(1):126. doi: https://doi.org/10.3390/genes13010126

 

2021

M. Munz*, M. Khodaygani*, Z. Aherrahrou, H. Busch and I. Wohlers.
In silico candidate variant and gene identification using inbred mouse strains.
PeerJ. 2021;9:e11017. doi: https://doi.org/10.7717/peerj.11017

M. Ohms, C. Ferreira, H. Busch, I. Wohlers, A. C. Guerra de Souza, R. Silvestre and T. Laskay.
Enhanced glycolysis is required for antileishmanial functions of neutrophils upon infection with Leishmania donovani.
Front Immunol. 2021;12:632512. doi: https://doi.org/10.3389/fimmu.2021.632512

D. Prokopenko, S. L. Morgan, K. Mullin, O. Hofmann, B. Chapman, R. Kirchner, S. Amberkar, I. Wohlers, C. Lange, W. Hide, L. Bertram and R. E. Tanzi.
Whole-genome sequencing reveals new Alzheimer’s disease-associated rare variants in loci related to synaptic function and neuronal development.
Alzheimers Dement. 2021;17(9):1509-1527. doi: https://doi.org/10.1002/alz.12319

 

2020

I. Wohlers, A. Künstner, M. Munz, M. Olbrich, A. Fähnrich, V. Calonga-Solís, C. Ma, M. Hirose, S. El-Mosallamy, M. Salama, H. Busch* and S. Ibrahim*. (* joint last authors)
A personal and population-based Egyptian genome reference.
Nat Commun. 2020;11(1):4719. doi: https://doi.org/10.1038/s41467-020-17964-1

M. Munz, I. Wohlers, E. Simon, T. Reinberger, H. Busch, A. S. Schaefer and J. Erdmann.
Qtlizer: comprehensive QTL annotation of GWAS results.
Sci Rep. 2020;10(1):20417. doi: https://doi.org/10.1038/s41598-020-75770-7

S. T. Jünger, F. Andreiuolo, M. Mynarek, I. Wohlers, S. Rahmann, L. Klein-Hitpass, E. Dörner, A. Zur Mühlen, N. Velez-Char, K. von Hoff, M. Warmuth-Metz, R. D. Kortmann, B. Timmermann, A. von Bueren, S. Rutkowski, T. Pietsch.
CDKN2A deletion in supratentorial ependymoma with RELA alteration indicates a dismal prognosis: a retrospective analysis of the HIT ependymoma trial cohort.
Acta Neuropathol. 2020;140(3):405-407. doi: https://doi.org/10.1007/s00401-020-02169-z

I. Wohlers, C. Schulz, F. Kilpert and L. Bertram.
Alzheimer's disease risk SNPs show no strong effect on miRNA expression in human lymphoblastoid cell lines.
Neurobiol Aging. 2020;86:202.e1-202.e3. doi: https://doi.org/10.1016/j.neurobiolaging.2019.08.013