Priority Research Area Infections

Cellular Microbiology

Mission   Projects   Funding   Techniques   Publications    Staff


Infection Biology

  • Safety lab to work with BSL3 microorganisms such as Mycobacterium tuberculosis
  • Aerosol infection model for tuberculosis (BSL3)
  • Vaccine and anti-microbial drug testing
  • Microbiome analysis (16s RNA sequencing, metagenomics, FISH, bioinformatics)
  • In vivo and in vitro imaging (under BSL3 conditions)
  • In vitro Infection models in primary cells from mouse and human (BSL3)
  • In vivo infection models for Klebsiella pneumonia infection
  • Stenotrophomonas maltophilia and mixed biofilm studies between bacteria and yeasts
  • Air-liquid interface lung epithelial cell model for biofilm studies
  • Bacteriophage collection

Infection Immunology

  • FACS (BSL2 and 3)
  • Histology Immunohistology
  • Cytokine- and chemokine assays
  • T-cell-Assays
  • Quantitative Real-time PCR
  • RNAseq

Cellular microbiology

  • Intracellular trafficking studies of pathogens in host cells, confocal microscopy
  • Live cell microscopy (BSL2 and 3)
  • Primary cell cultures: human, mouse; macrophages, neutrophils, dendritic cells, lymphocytes, lung epithelial cells
  • Subcellular fractionation, phagosome isolation
  • Cell death assays
  • siRNA-based knock-down
  • Reporter strain of tuberculosis and S. maltophilia


  • SDS-PAGE, western blot
  • Liposome technology
  • Glycolipid isolation
  • Thin layer chromatography