Priority Research Area Infections

2023

EUCAST AMST and ESCMYC study groups 2023, 'Towards clinical breakpoints for non-tuberculous mycobacteria - Determination of epidemiological cut off values for the Mycobacterium avium complex and Mycobacterium abscessus using broth microdilution', CLINICAL MICROBIOLOGY AND INFECTION . https://doi.org/10.1016/j.cmi.2023.02.007

Koehler, N, Andres, S, Merker, M, Dreyer, V, John, A, Kuhns, M, Krieger, D, Choong, E, Verougstraete, N, Zur Wiesch, PA, Wicha, SG, König, C, Kalsdorf, B, Sanchez Carballo, PM, Schaub, D, Werngren, J, Schön, T, Peloquin, CA, Schönfeld, N, Verstraete, AG, Decosterd, LA, Aarnoutse, R, Niemann, S, Maurer, FP & Lange, C 2023, 'Pretomanid-Resistant Tuberculosis', Journal of infection. https://doi.org/10.1016/j.jinf.2023.01.039

Maier, C, Chesov, D, Schaub, D, Kalsdorf, B, Andres, S, Friesen, I, Reimann, M & Lange, C 2023, 'Long-term treatment outcomes in patients with multidrug-resistant tuberculosis', CLINICAL MICROBIOLOGY AND INFECTION . https://doi.org/10.1016/j.cmi.2023.02.013

TBNET and RESIST-TB networks 2023, 'Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement', Lancet Infectious Diseases, Jg. 23, Nr. 4, S. e122-e137. https://doi.org/10.1016/S1473-3099(22)00875-1

 

2022

Akwani, WC, van Vliet, AHM, Joel, JO, Andres, S, Diricks, M, Maurer, FP, Chambers, MA & Hingley-Wilson, SM 2022, 'The Use of Comparative Genomic Analysis for the Development of Subspecies-Specific PCR Assays for Mycobacterium abscessus', Frontiers in Cellular and Infection Microbiology, Jg. 12, S. 816615. https://doi.org/10.3389/fcimb.2022.816615

Antimycobacterial Susceptibility Testing Group 2022, 'Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment', The European respiratory journal, Jg. 59, Nr. 4, 2200166. https://doi.org/10.1183/13993003.00166-2022

Bateson, A, Ortiz Canseco, J, McHugh, TD, Witney, AA, Feuerriegel, S, Merker, M, Kohl, TA, Utpatel, C, Niemann, S, Andres, S, Kranzer, K, Maurer, FP, Ghodousi, A, Borroni, E, Cirillo, DM, Wijkander, M, Toro, JC, Groenheit, R, Werngren, J, Machado, D, Viveiros, M, Warren, RM, Sirgel, F, Dippenaar, A, Köser, CU, Sun, E & Timm, J 2022, 'Ancient and recent differences in the intrinsic susceptibility of Mycobacterium tuberculosis complex to pretomanid', JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, Jg. 77, Nr. 6, S. 1685-1693. https://doi.org/10.1093/jac/dkac070

Brandenburg, J, Heyckendorf, J, Marwitz, F, Zehethofer, N, Linnemann, L, Gisch, N, Karaköse, H, Reimann, M, Kranzer, K, Kalsdorf, B, Sanchez-Carballo, P, Weinkauf, M, Scholz, V, Malm, S, Homolka, S, Gaede, KI, Herzmann, C, Schaible, UE, Hölscher, C, Reiling, N & Schwudke, D 2022, 'Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis', ACS infectious diseases, Jg. 8, Nr. 7, S. 1303-1315. https://doi.org/10.1021/acsinfecdis.2c00075

Chesov, E, Chesov, D, Maurer, FP, Andres, S, Utpatel, C, Barilar, I, Donica, A, Reimann, M, Niemann, S, Lange, C, Crudu, V, Heyckendorf, J & Merker, M 2022, 'Emergence of bedaquiline resistance in a high tuberculosis burden country', The European respiratory journal, Jg. 59, Nr. 3, 2100621. https://doi.org/10.1183/13993003.00621-2021

Diricks, M, Merker, M, Wetzstein, N, Kohl, TA, Niemann, S & Maurer, FP 2022, 'Delineating Mycobacterium abscessus population structure and transmission employing high-resolution core genome multilocus sequence typing', Nature communications, Jg. 13, Nr. 1, S. 4936. https://doi.org/10.1038/s41467-022-32122-5

European Laboratory Initiative on TB, HIV and viral hepatitis core group members 2022, 'Integrated use of laboratory services for multiple infectious diseases in the WHO European Region during the COVID-19 pandemic and beyond', Eurosurveillance, Jg. 27, Nr. 29, 2100930. https://doi.org/10.2807/1560-7917.ES.2022.27.29.2100930

European Laboratory Initiative on TB, HIV and Viral Hepatitis(3) & Niemann, S 2022, 'Diagnostic Capacities for Multidrug-Resistant Tuberculosis in the World Health Organization European Region: Action is Needed by all Member States', Journal of Molecular Diagnostics, Jg. 24, Nr. 11, S. 1189-1194. https://doi.org/10.1016/j.jmoldx.2022.07.005

Finci, I, Albertini, A, Merker, M, Andres, S, Bablishvili, N, Barilar, I, Cáceres, T, Crudu, V, Gotuzzo, E, Hapeela, N, Hoffmann, H, Hoogland, C, Kohl, TA, Kranzer, K, Mantsoki, A, Maurer, FP, Nicol, MP, Noroc, E, Plesnik, S, Rodwell, T, Ruhwald, M, Savidge, T, Salfinger, M, Streicher, E, Tukvadze, N, Warren, R, Zemanay, W, Zurek, A, Niemann, S & Denkinger, CM 2022, 'Investigating resistance in clinical Mycobacterium tuberculosis complex isolates with genomic and phenotypic antimicrobial susceptibility testing: a multicentre observational study', The Lancet. Microbe, Jg. 3, Nr. 9, S. e672-e682. https://doi.org/10.1016/S2666-5247(22)00116-1

Gisch, N, Utpatel, C, Gronbach, LM, Kohl, TA, Schombel, U, Malm, S, Dobos, KM, Hesser, DC, Diel, R, Götsch, U, Gerdes, S, Shuaib, YA, Ntinginya, NE, Khosa, C, Viegas, S, Kerubo, G, Ali, S, Al-Hajoj, SA, Ndung’u, PW, Rachow, A, Hoelscher, M, Maurer, FP, Schwudke, D, Niemann, S, Reiling, N & Homolka, S 2022, 'Sub-Lineage Specific Phenolic Glycolipid Patterns in the Mycobacterium tuberculosis Complex Lineage 1', Frontiers in Microbiology, Jg. 13, S. 832054. https://www.frontiersin.org/article/10.3389/fmicb.2022.832054

Hansen, J, Kolbe, K, König, IR, Scherließ, R, Hellfritzsch, M, Malm, S, Müller-Loennies, S, Zallet, J, Hillemann, D, Wiesmüller, K-H, Herzmann, C, Brandenburg, J & Reiling, N 2022, 'Lipobiotin-capture magnetic bead assay for isolation, enrichment and detection of Mycobacterium tuberculosis from saliva', PLOS ONE, Jg. 17, Nr. 7, S. e0265554. https://doi.org/10.1371/journal.pone.0265554

Kanyala, E, Shuaib, YA, Schwarz, NG, Andres, S, Richter, E, Sawadogo, B, Sawadogo, M, Germaine, M, Lassina, O, Poppert, S & Frickmann, H 2022, 'Prevalence and Molecular Characterization of Mycobacterium bovis in Slaughtered Cattle Carcasses in Burkina Faso; West Africa', Microorganisms, Jg. 10, Nr. 7, 1378. https://doi.org/10.3390/microorganisms10071378

Klein, C, Borsche, M, Balck, A, Föh, B, Rahmöller, J, Peters, E, Knickmann, J, Lane, M, Vollstedt, E-J, Elsner, SA, Käding, N, Hauswaldt, S, Lange, T, Hundt, JE, Lehrian, S, Giese, J, Mischnik, A, Niemann, S, Maurer, F, Homolka, S, Paulowski, L, Kramer, J, Twesten, C, Sina, C, Gillessen-Kaesbach, G, Busch, H, Ehlers, M, Taube, S, Rupp, J & Katalinic, A 2022, 'One-year surveillance of SARS-CoV-2 transmission of the ELISA cohort: A model for population-based monitoring of infection risk', Science advances, Jg. 8, Nr. 15, S. eabm5016. https://doi.org/10.1126/sciadv.abm5016

Lagune, M, Le Moigne, V, Johansen, MD, Vásquez Sotomayor, F, Daher, W, Petit, C, Cosentino, G, Paulowski, L, Gutsmann, T, Wilmanns, M, Maurer, FP, Herrmann, J-L, Girard-Misguich, F & Kremer, L 2022, 'The ESX-4 substrates, EsxU and EsxT, modulate Mycobacterium abscessus fitness', PLOS PATHOGENS, Jg. 18, Nr. 8, S. e1010771. https://doi.org/10.1371/journal.ppat.1010771

Merker, M, Rasigade, J-P, Barbier, M, Cox, H, Feuerriegel, S, Kohl, TA, Shitikov, E, Klaos, K, Gaudin, C, Antoine, R, Diel, R, Borrell, S, Gagneux, S, Nikolayevskyy, V, Andres, S, Crudu, V, Supply, P, Niemann, S & Wirth, T 2022, 'Transcontinental spread and evolution of Mycobacterium tuberculosis W148 European/Russian clade toward extensively drug resistant tuberculosis', Nature communications, Jg. 13, Nr. 1, S. 5105. https://doi.org/10.1038/s41467-022-32455-1

Paulowski, L, Beckham, KSH, Johansen, MD, Berneking, L, Van, N, Degefu, Y, Staack, S, Sotomayor, FV, Asar, L, Rohde, H, Aldridge, BB, Aepfelbacher, M, Parret, A, Wilmanns, M, Kremer, L, Combrink, K & Maurer, FP 2022, 'C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus', PNAS nexus, Jg. 1, Nr. 4, S. pgac130. https://doi.org/10.1093/pnasnexus/pgac130

Schaberg, T, Brinkmann, F, Feiterna-Sperling, C, Geerdes-Fenge, H, Hartmann, P, Häcker, B, Hauer, B, Haas, W, Heyckendorf, J, Lange, C, Maurer, FP, Nienhaus, A, Otto-Knapp, R, Priwitzer, M, Richter, E, Salzer, HJF, Schoch, O, Schönfeld, N, Stahlmann, R & Bauer, T 2022, 'Tuberkulose im Erwachsenenalter', Pneumologie (Stuttgart, Germany), Jg. 76, Nr. 11, S. 727-819. https://doi.org/10.1055/a-1934-8303

Shuaib, YA, Utpatel, C, Kohl, TA, Barilar, I, Diricks, M, Ashraf, N, Wieler, LH, Kerubo, G, Mesfin, EA, Diallo, AB, Al-Hajoj, S, Ndung'u, P, Fitzgibbon, MM, Vaziri, F, Sintchenko, V, Martinez, E, Viegas, SO, Zhou, Y, Azmy, A, Al-Amry, K, Godreuil, S, Varma-Basil, M, Narang, A, Ali, S, Beckert, P, Dreyer, V, Kabwe, M, Bates, M, Hoelscher, M, Rachow, A, Gori, A, Tekwu, EM, Sidze, LK, Jean-Paul, AA, Beng, VP, Ntoumi, F, Frank, M, Diallo, AG, Mboup, S, Tessema, B, Beyene, D, Khan, SN, Diel, R, Supply, P, Maurer, FP, Hoffmann, H, Niemann, S & Merker, M 2022, 'Origin and Global Expansion of Mycobacterium tuberculosis Complex Lineage 3', Genes, Jg. 13, Nr. 6, 990. https://doi.org/10.3390/genes13060990

Sibandze, DB, Kay, A, Dreyer, V, Sikhondze, W, Dlamini, Q, DiNardo, A, Mtetwa, G, Lukhele, B, Vambe, D, Lange, C, Glenn Dlamini, M, Ness, T, Mejia, R, Kalsdorf, B, Heyckendorf, J, Kuhns, M, Maurer, FP, Dlamini, S, Maphalala, G, Niemann, S & Mandalakas, A 2022, 'Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing', Genome medicine, Jg. 14, Nr. 1, S. 52. https://doi.org/10.1186/s13073-022-01054-6

Study Group on Mycobacteria of the European Society of Microbiology and Infectious Diseases (ESGMYC), European Society of Mycobacteriology (ESM), European Respiratory Society (ERS) and 2022, 'Rifapentine access in Europe: growing concerns over key tuberculosis treatment component', The European respiratory journal, Jg. 59, Nr. 5, S. 2200388. https://doi.org/10.1183/13993003.00388-2022

Walter, K, Kokesch-Himmelreich, J, Treu, A, Waldow, F, Hillemann, D, Jakobs, N, Lemm, A-K, Schwudke, D, Römpp, A & Hölscher, C 2022, 'Interleukin-13 overexpressing mice represent an advanced pre-clinical model for detecting the distribution of anti-mycobacterial drugs within centrally necrotizing granulomas', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 66, Nr. 6, S. e0158821. https://doi.org/10.1128/AAC.01588-21

Welte, T, Dinkel, J, Maurer, F, Richter, E, Rohde, G, Schwarz, C, Taube, C & Diel, R 2022, 'Versorgung von Patienten/innen mit einer durch nichttuberkulöse Mykobakterien verursachten Lungenerkrankung in Deutschland – ein transsektorales patientenorientiertes Versorgungskonzept', Pneumologie (Stuttgart, Germany), Jg. 76, Nr. 8, S. 534-546. https://doi.org/10.1055/a-1855-0858

Wetzstein, N, Diricks, M, Kohl, TA, Wichelhaus, TA, Andres, S, Paulowski, L, Schwarz, C, Lewin, A, Kehrmann, J, Kahl, BC, Dichtl, K, Hügel, C, Eickmeier, O, Smaczny, C, Schmidt, A, Zimmermann, S, Nährlich, L, Hafkemeyer, S, Niemann, S, Maurer, FP & Hogardt, M 2022, 'Molecular Epidemiology of Mycobacterium abscessus Isolates Recovered from German Cystic Fibrosis Patients', Microbiology spectrum, Jg. 10, Nr. 4, S. e0171422. https://doi.org/10.1128/spectrum.01714-22

 

2021

Apostolopoulos, N, Prenger-Berninghoff, E, Wildermuth, B, Moser, I, Hillemann, D, Nobach, D, Herden, C, Ewers, C & Thom, N 2021, 'Mycobacterium setense isolated from a cat with atypical mycobacterial panniculitis', Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere, Jg. 49, Nr. 5, S. 390-396. https://doi.org/10.1055/a-1528-1763

Chesov, E, Chesov, D, Maurer, FP, Andres, S, Utpatel, C, Barilar, I, Donica, A, Reimann, M, Niemann, S, Lange, C, Crudu, V, Heyckendorf, J & Merker, M 2021, 'Emergence of bedaquiline-resistance in a high-burden country of tuberculosis', The European respiratory journal. https://doi.org/10.1183/13993003.00621-2021

Cornejo-Granados, F, Kohl, TA, Sotomayor, FV, Andres, S, Hernández-Pando, R, Hurtado-Ramirez, JM, Utpatel, C, Niemann, S, Maurer, FP & Ochoa-Leyva, A 2021, 'Secretome characterization of clinical isolates from the Mycobacterium abscessus complex provides insight into antigenic differences', BMC GENOMICS , Jg. 22, Nr. 1, S. 385. https://doi.org/10.1186/s12864-021-07670-7

Diel, R, Sotgiu, G, Andres, S, Hillemann, D & Maurer, FP 2021, 'Cost of multidrug resistant tuberculosis in Germany - an update', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 103, S. 102-109. https://doi.org/10.1016/j.ijid.2020.10.084

DZIF-TB cohort study group, Heyckendorf, J, Reimann, M, Marwitz, S & Lange, C 2021, 'Pathogen-free diagnosis of tuberculosis', Lancet Infectious Diseases, Jg. 21, Nr. 8, S. 1066. https://doi.org/10.1016/S1473-3099(21)00337-6

ECDC molecular surveillance project participants, Tagliani, E, Anthony, R, Kohl, TA, de Neeling, A, Nikolayevskyy, V, Ködmön, C, Maurer, FP, Niemann, S, van Soolingen, D, van der Werf, MJ & Cirillo, DM 2021, 'Use of a Whole Genome Sequencing-based approach for Mycobacterium tuberculosis surveillance in Europe in 2017-2019: an ECDC pilot study', The European respiratory journal, Jg. 57, Nr. 1. https://doi.org/10.1183/13993003.02272-2020

ERLTB-Net-2 study participants, Nikolayevskyy, V, Holicka, Y, van Soolingen, D, van der Werf, MJ, Ködmön, C, Surkova, E, Hillemann, D, Groenheit, R & Cirillo, D 2021, 'Impact of the COVID-19 pandemic on tuberculosis laboratory services in Europe', The European respiratory journal, Jg. 57, Nr. 1. https://doi.org/10.1183/13993003.03890-2020

European Laboratory Initiative on TB, HIV and Viral Hepatitis, Maurer, FP, Shubladze, N, Kalmambetova, G, Felker, I, Kuchukhidze, G, Drobniewski, F, Yedilbayev, A & Ehsani, S 2021, 'Impact of the COVID-19 pandemic on tuberculosis national reference laboratory services in the WHO European Region, March to November 2020', Eurosurveillance, Jg. 26, Nr. 24. https://doi.org/10.2807/1560-7917.ES.2021.26.24.2100426

Feuerriegel, S, Kohl, TA, Utpatel, C, Andres, S, Maurer, FP, Heyckendorf, J, Jouet, A, Badalato, N, Foray, L, Kamara, RF, Conteh, OS, Supply, P & Niemann, S 2021, 'Rapid genomic first- and second-line drug resistance prediction from clinical Mycobacterium tuberculosis specimens using Deeplex®-MycTB', The European respiratory journal, Jg. 57, Nr. 1. https://doi.org/10.1183/13993003.01796-2020

Goldmann, T, Hillemann, D, Maurer, F, Kalsdorf, B, Krupar, R, Stellmacher, F & Perner, S 2021, 'Mycobacterium szulgai als Posititivkontrolle zur Detektion von Kontaminationen beim Nachweis des Mycobacterium tuberculosis-Komplexes durch eine spezifische 16S-rDNA-PCR an FFPE-Material', Der Pathologe, Jg. 42, Nr. 1, S. 83-85. https://doi.org/10.1007/s00292-021-00912-1

Grobbel, H-P, Merker, M, Köhler, N, Andres, S, Hoffmann, H, Heyckendorf, J, Reimann, M, Barilar, I, Dreyer, V, Hillemann, D, Kalsdorf, B, Kohl, TA, Sanchez-Carballo, P, Schaub, D, Todt, K, Utpatel, C, Maurer, FP, Lange, C & Niemann, S 2021, 'Design of multidrug-resistant tuberculosis treatment regimens based on DNA sequencing', CLINICAL INFECTIOUS DISEASES , Jg. 73, Nr. 7, S. 1194-1202. https://doi.org/10.1093/cid/ciab359

Heyckendorf, J, Marwitz, S, Reimann, M, Avsar, K, DiNardo, A, Günther, G, Hoelscher, M, Ibraim, E, Kalsdorf, B, Kaufmann, SHE, Kontsevaya, I, van Leth, F, Mandalakas, AM, Maurer, FP, Müller, M, Nitschkowski, D, Olaru, ID, Popa, C, Rachow, A, Rolling, T, Rybniker, J, Salzer, HJF, Sanchez-Carballo, P, Schuhmann, M, Schaub, D, Spinu, V, Suárez, I, Terhalle, E, Unnewehr, M, Weiner, J, Goldmann, T & Lange, C 2021, 'Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model', The European respiratory journal, Jg. 58, Nr. 3. https://doi.org/10.1183/13993003.03492-2020

Lagune, M, Petit, C, Sotomayor, FV, Johansen, MD, Beckham, KSH, Ritter, C, Girard-Misguich, F, Wilmanns, M, Kremer, L, Maurer, FP & Herrmann, J-L 2021, 'Conserved and specialized functions of Type VII secretion systems in non-tuberculous mycobacteria', MICROBIOLOGY-SGM , Jg. 167, Nr. 7. https://doi.org/10.1099/mic.0.001054

Marcordes, S, Lueders, I, Grund, L, Sliwa, A, Kuehn-Velten, WN, Hillemann, D, Maurer, FP & Barth, SA 2021, 'TREATMENT OF MYCOBACTERIOSIS CAUSED BY MYCOBACTERIUM AVIUM SSP. HOMINISSUIS IN A GROUP OF CAPTIVE LOWLAND TAPIRS (TAPIRUS TERRESTRIS)', Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, Jg. 52, Nr. 3, S. 939-948. https://doi.org/10.1638/2020-0198

Nadarajan, D, Hillemann, D, Kamara, R, Foray, L, Conteh, OS, Merker, M, Niemann, S, Lau, J, Njoya, M, Kranzer, K, Somoskovi, A & Maurer, FP 2021, 'Evaluation of the Roche cobas MTB and MTB-RIF/INH assays in samples from Germany and Sierra Leone', JOURNAL OF CLINICAL MICROBIOLOGY, Jg. 59, Nr. 5. https://doi.org/10.1128/JCM.02983-20

Sanchini, A, Jandrasits, C, Tembrockhaus, J, Kohl, TA, Utpatel, C, Maurer, FP, Niemann, S, Haas, W, Renard, BY & Kröger, S 2021, 'Improving tuberculosis surveillance by detecting international transmission using publicly available whole genome sequencing data', Eurosurveillance, Jg. 26, Nr. 2. https://doi.org/10.2807/1560-7917.ES.2021.26.2.1900677

Schromm, AB, Paulowski, L, Kaconis, Y, Kopp, F, Koistinen, M, Donoghue, A, Keese, S, Nehls, C, Wernecke, J, Garidel, P, Sevcsik, E, Lohner, K, Sanchez-Gomez, S, Martinez-de-Tejada, G, Brandenburg, K, Brameshuber, M, Schütz, GJ, Andrä, J & Gutsmann, T 2021, 'Cathelicidin and PMB neutralize endotoxins by multifactorial mechanisms including LPS interaction and targeting of host cell membranes', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jg. 118, Nr. 27. https://doi.org/10.1073/pnas.2101721118

Sonnenkalb, L, Strohe, G, Dreyer, V, Andres, S, Hillemann, D, Maurer, FP, Niemann, S & Merker, M 2021, 'Microevolution of Mycobacterium tuberculosis Subpopulations and Heteroresistance in a Patient Receiving 27 Years of Tuberculosis Treatment in Germany', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 65, Nr. 7, S. e0252020. https://doi.org/10.1128/AAC.02520-20

Steindor, M, Stehling, F, Olivier, M, Kehrmann, J, Diricks, M, Maurer, FP, Horn, PA, Straßburg, S, Welsner, M, Sutharsan, S & Lindemann, M 2021, 'Species-Specific Interferon-Gamma Release Assay for the Diagnosis of Mycobacterium abscessus Complex Infection', Frontiers in Microbiology, S. 692395. https://doi.org/10.3389/fmicb.2021.692395

Stellmacher, F, Kirfel, J, Kalsdorf, B, Maurer, FP, Perner, S & Goldmann, T 2021, 'Molekularpathologie der Tuberkulose: Stellenwert, Methodik und Grenzen', Der Pathologe, Jg. 42, Nr. 1, S. 78-82. https://doi.org/10.1007/s00292-021-00911-2

Walter, K, Kokesch-Himmelreich, J, Treu, A, Waldow, F, Hillemann, D, Jakobs, N, Lemm, A-K, Schwudke, D, Römpp, A & Hölscher, C 2021, 'Interleukin-13 overexpressing mice represent an advanced pre-clinical model for detecting the distribution of anti-mycobacterial drugs within centrally necrotizing granulomas', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, S. AAC0158821. https://doi.org/10.1128/AAC.01588-21

 

 

2020

Andres, S, Merker, M, Heyckendorf, J, Kalsdorf, B, Rumetshofer, R, Indra, A, Hofmann-Thiel, S, Hoffmann, H, Lange, C, Niemann, S & Maurer, FP 2020, 'Bedaquiline-resistant Tuberculosis:Dark Clouds on the Horizon', American journal of respiratory and critical care medicine, Jg. 201, Nr. 12, S. 1564-1568. https://doi.org/10.1164/rccm.201909-1819LE

Barth, SA, Menge, C, Hillemann, D, Lauda, A & Pfleghaar, S 2020, 'Tuberculosis in a pet ferret (Mustela putorius furo)', Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere, Jg. 48, Nr. 1, S. 50-55. https://doi.org/10.1055/a-1069-6630

Beckert, P, Sanchez-Padilla, E, Merker, M, Dreyer, V, Kohl, TA, Utpatel, C, Köser, CU, Barilar, I, Ismail, N, Omar, SV, Klopper, M, Warren, RM, Hoffmann, H, Maphalala, G, Ardizzoni, E, de Jong, BC, Kerschberger, B, Schramm, B, Andres, S, Kranzer, K, Maurer, FP, Bonnet, M & Niemann, S 2020, 'MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era', Genome medicine, Jg. 12, Nr. 1, S. 104. https://doi.org/10.1186/s13073-020-00793-8

ECDC molecular surveillance project participants, Tagliani, E, Anthony, R, Kohl, TA, de Neeling, A, Nikolayevskyy, V, Ködmön, C, Maurer, FP, Niemann, S, van Soolingen, D, van der Werf, MJ & Cirillo, DM 2020, 'Use of a Whole Genome Sequencing-based approach for Mycobacterium tuberculosis surveillance in Europe in 2017-2019: an ECDC pilot study', The European respiratory journal. https://doi.org/10.1183/13993003.02272-2020

Feuerriegel, S, Kohl, TA, Utpatel, C, Andres, S, Maurer, FP, Heyckendorf, J, Jouet, A, Badalato, N, Foray, L, Kamara, RF, Conteh, OS, Supply, P & Niemann, S 2020, 'Rapid genomic first- and second-line drug resistance prediction from clinical Mycobacterium tuberculosis specimens using Deeplex®-MycTB', The European respiratory journal. https://doi.org/10.1183/13993003.01796-2020

Godfroid, M, Dagan, T, Merker, M, Kohl, TA, Diel, R, Maurer, FP, Niemann, S & Kupczok, A 2020, 'Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak', PLOS PATHOGENS, Jg. 16, Nr. 9, S. e1008357. https://doi.org/10.1371/journal.ppat.1008357

Homolka, S, Paulowski, L, Andres, S, Hillemann, D, Jou, R, Günther, G, Claassens, M, Kuhns, M, Niemann, S & Maurer, FP 2020, 'Two Pandemics, One Challenge-Leveraging Molecular Test Capacity of Tuberculosis Laboratories for Rapid COVID-19 Case-Finding', EMERGING INFECTIOUS DISEASES, Jg. 26, Nr. 11. https://doi.org/10.3201/eid2611.202602

Jäger, K, Gläsel, A, Hillemann, D, Martin, N & Theuerkauff, J 2020, 'Erstbeschreibung des kaninen leproiden Granuloms in Deutschland: 2 Fallberichte', Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere, Jg. 48, Nr. 3, S. 196-202. https://doi.org/10.1055/a-1162-1338

Johansen, MD, Daher, W, Roquet-Banères, F, Raynaud, C, Alcaraz, M, Maurer, FP & Kremer, L 2020, 'Rifabutin Is Bactericidal against Intracellular and Extracellular Forms of Mycobacterium abscessus', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 64, Nr. 11. https://doi.org/10.1128/AAC.00363-20

Kohl, TA, Kranzer, K, Andres, S, Wirth, T, Niemann, S & Moser, I 2020, 'Population structure of Mycobacterium bovis in Germany: A long-term study using Whole Genome Sequencing combined with conventional molecular typing methods', JOURNAL OF CLINICAL MICROBIOLOGY. https://doi.org/10.1128/JCM.01573-20

Leo, F, Stegemann, MS & Maurer, F 2020, 'Antibiotic Stewardship bei ambulant erworbener Pneumonie', Deutsche medizinische Wochenschrift (1946), Jg. 145, Nr. 6, S. 383-392. https://doi.org/10.1055/a-0993-1164

M. chimaera ISCVID investigators 2020, 'International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass', Journal of hospital infection, Jg. 104, Nr. 2, S. 214-235. https://doi.org/10.1016/j.jhin.2019.10.009

Marcordes, S, Lueders, I, Grund, L, Sliwa, A, Maurer, FP, Hillemann, D, Möbius, P & Barth, SA 2020, 'Clinical outcome and diagnostic methods of atypical mycobacteriosis due to Mycobacterium avium ssp. hominissuis in a group of captive lowland tapirs (Tapirus terrestris)', Transboundary and Emerging Diseases. https://doi.org/10.1111/tbed.13786Merker, M, Kohl, TA, Barilar, I, Andres, S, Fowler, PW, Chryssanthou, E, Ängeby, K, Jureen, P, Moradigaravand, D, Parkhill, J, Peacock, SJ, Schön, T, Maurer, FP, Walker, T, Köser, C & Niemann, S 2020, 'Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex', Genome medicine, Jg. 12, Nr. 1, S. 27. https://doi.org/10.1186/s13073-020-00726-5

Merker, M, Kohl, TA, Barilar, I, Andres, S, Fowler, PW, Chryssanthou, E, Ängeby, K, Jureen, P, Moradigaravand, D, Parkhill, J, Peacock, SJ, Schön, T, Maurer, FP, Walker, T, Köser, C & Niemann, S 2020, 'Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex', Genome medicine, Jg. 12, Nr. 1, S. 27. https://doi.org/10.1186/s13073-020-00726-5

Otto-Knapp, R, Knappik, M, Häcker, B, Starzacher, K, Bauer, T, Lange, C, Maurer, FP, Schaberg, T & Günther, G 2020, 'Die neuen WHO-Empfehlungen für schnelle Diagnostik und Therapie resistenter Tuberkulose in Deutschland, Österreich und der Schweiz', Pneumologie (Stuttgart, Germany), Jg. 74, Nr. 11, S. 742-749. https://doi.org/10.1055/a-1266-5207

Paulowski, L, Donoghue, A, Nehls, C, Groth, S, Koistinen, M, Hagge, SO, Böhling, A, Winterhalter, M & Gutsmann, T 2020, 'The Beauty of Asymmetric Membranes: Reconstitution of the Outer Membrane of Gram-Negative Bacteria', Frontiers in cell and developmental biology, Jg. 8, S. 586. https://doi.org/10.3389/fcell.2020.00586

Shuaib, YA, Khalil, EAG, Wieler, LH, Schaible, UE, Bakheit, MA, Mohamed-Noor, SE, Abdalla, MA, Kerubo, G, Andres, S, Hillemann, D, Richter, E, Kranzer, K, Niemann, S & Merker, M 2020, 'Mycobacterium tuberculosis Complex Lineage 3 as Causative Agent of Pulmonary Tuberculosis, Eastern Sudan1', EMERGING INFECTIOUS DISEASES, Jg. 26, Nr. 3, S. 427-436. https://doi.org/10.3201/eid2603.191145

Wetzstein, N, Kohl, TA, Schultze, TG, Andres, S, Bellinghausen, C, Hügel, C, Kempf, VAJ, Lehn, A, Hogardt, M, Serve, H, Vehreschild, MJGT, Wolf, T, Niemann, S, Maurer, FP & Wichelhaus, TA 2020, 'Antimicrobial susceptibility and phylogenetic relations in a German cohort infected with Mycobacterium abscessus', JOURNAL OF CLINICAL MICROBIOLOGY. https://doi.org/10.1128/JCM.01813-20

Wetzstein, N, Kohl, TA, Andres, S, Schultze, TG, Geil, A, Kim, E, Biciusca, T, Hügel, C, Hogardt, M, Lehn, A, Vehreschild, MJGT, Wolf, T, Niemann, S, Maurer, FP & Wichelhaus, TA 2020, 'Comparative analysis of phenotypic and genotypic antibiotic susceptibility patterns in Mycobacterium avium complex', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 93, S. 320-328. https://doi.org/10.1016/j.ijid.2020.02.059

Wetzstein, N, Kohl, TA, Schultze, TG, Andres, S, Bellinghausen, C, Hügel, C, Kempf, VAJ, Lehn, A, Hogardt, M, Serve, H, Vehreschild, MJGT, Wolf, T, Niemann, S, Maurer, FP & Wichelhaus, TA 2020, 'Antimicrobial susceptibility and phylogenetic relations in a German cohort infected with Mycobacterium abscessus', JOURNAL OF CLINICAL MICROBIOLOGY, Jg. 58, Nr. 12. https://doi.org/10.1128/JCM.01813-20

 

2019

Dupont, C, Chen, Y, Xu, Z, Roquet-Banères, F, Blaise, M, Witt, A-K, Dubar, F, Biot, C, Guérardel, Y, Maurer, FP, Chng, S-S & Kremer, L 2019, 'A piperidinol-containing molecule is active against Mycobacterium tuberculosis by inhibiting the mycolic acid flippase activity of MmpL3', The Journal of biological chemistry, Jg. 294, Nr. 46, S. 17512-17523. https://doi.org/10.1074/jbc.RA119.010135

Diel, R, Kohl, TA, Maurer, FP, Merker, M, Meywald Walter, K, Hannemann, J, Nienhaus, A, Supply, P & Niemann, S 2019, 'Accuracy of whole genome sequencing to determine recent tuberculosis transmission: an 11-year population-based study in Hamburg, Germany', The European respiratory journal, Jg. 54, Nr. 5. https://doi.org/10.1183/13993003.01154-2019

Lange, C, Kalsdorf, B, Maurer, FP & Heyckendorf, J 2019, 'Tuberkulose', Internist, Jg. 60, Nr. 11, S. 1155-1175. https://doi.org/10.1007/s00108-019-00685-z

Engström, A, Antonenka, U, Kadyrov, A, Kalmambetova, G, Kranzer, K, Merker, M, Kabirov, O, Parpieva, N, Rajabov, A, Sahalchyk, E, Sayfudtinov, Z, Niemann, S & Hoffmann, H 2019, 'Population structure of drug-resistant Mycobacterium tuberculosis in Central Asia', BMC INFECTIOUS DISEASES , Jg. 19, Nr. 1, S. 908. https://doi.org/10.1186/s12879-019-4480-7

Homolka, S, Zallet, J, Albert, H, Witt, A-K & Kranzer, K 2019, 'Introduction of quality management in a National Reference Laboratory in Germany', PLOS ONE, Jg. 14, Nr. 10, S. e0222925. https://doi.org/10.1371/journal.pone.0222925

Polsfuss, S, Hofmann-Thiel, S, Merker, M, Krieger, D, Niemann, S, Rüssmann, H, Schönfeld, N, Hoffmann, H & Kranzer, K 2019, 'Emergence of Low-level Delamanid and Bedaquiline Resistance During Extremely Drug-resistant Tuberculosis Treatment', CLINICAL INFECTIOUS DISEASES , Jg. 69, S. 1229-1231. https://doi.org/10.1093/cid/ciz074

Combrink, KD, Ramos, AR, Spring, S, Schmidl, S, Elizondo, K, Morin, P, De Jesus, B & Maurer, FP 2019, 'Rifamycin derivatives active against pathogenic rapidly-growing mycobacteria', BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , Jg. 29, Nr. 16, S. 2112-2115. https://doi.org/10.1016/j.bmcl.2019.07.001

Maurer, FP, Mintken, E, Rupp, J, Olaru, I & Kranzer, K 2019, 'The landscape of diagnostic mycobacteriology in Germany-challenges of decentralised care', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 23, Nr. 8, S. 913-918. https://doi.org/10.5588/ijtld.18.0763

Asar, L, Pfefferle, S, Lütgehetmann, M, Hoffmann, A, Katchanov, J, Aepfelbacher, M, Rohde, H & Maurer, FP 2019, 'Influence of local epidemiology on the performance of common colistin drug susceptibility testing methods', PLOS ONE, Jg. 14, Nr. 6, S. e0217468. https://doi.org/10.1371/journal.pone.0217468

Havlicek, J, Dachsel, B, Slickers, P, Andres, S, Beckert, P, Feuerriegel, S, Niemann, S, Merker, M & Labugger, I 2019, 'Rapid microarray-based assay for detection of pyrazinamide resistant Mycobacterium tuberculosis', Diagnostic microbiology and infectious disease, Jg. 94, Nr. 2, S. 147-154. https://doi.org/10.1016/j.diagmicrobio.2018.12.011

Ismail, NA, Said, HM, Rodrigues, C, Omar, SV, Ajbani, K, Sukhadiad, N, Kohl, TA, Niemann, S, Kranzer, K, Diels, M, Rigouts, L, Rüsch-Gerdes, S & Siddiqi, S 2019, 'Multicentre study to establish interpretive criteria for clofazimine drug susceptibility testing', INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 23, Nr. 5, S. 594-599. https://doi.org/10.5588/ijtld.18.0417

Maurer, FP, Pohle, P, Kernbach, M, Sievert, D, Hillemann, D, Rupp, J, Hombach, M & Kranzer, K 2019, 'Differential drug susceptibility patterns of Mycobacterium chimaera and other members of the Mycobacterium avium-intracellulare complex', CLINICAL MICROBIOLOGY AND INFECTION , Jg. 25, Nr. 3, S. 379.e1-379.e7. https://doi.org/10.1016/j.cmi.2018.06.010

Khalil, ZG, Hill, TA, De Leon Rodriguez, LM, Lohman, R-J, Hoang, HN, Reiling, N, Hillemann, D, Brimble, M, Fairlie, D, Blumenthal, A & Capon, RJ 2019, 'Structure-activity relationships of wollamide cyclic hexapeptides with activity against drug-resistant and intracellular Mycobacterium tuberculosis', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 63, Nr. 3, S. e01773-18. https://doi.org/10.1128/AAC.01773-18

Köser, CU, Maurer, FP & Kranzer, K 2019, ''Those who cannot remember the past are condemned to repeat it': Drug-susceptibility testing for bedaquiline and delamanid', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 80 supplement, S. 32-35. https://doi.org/10.1016/j.ijid.2019.02.027

Maurer, FP 2019, 'Tuberkulose in Deutschland', Diagnostik im Dialog, S. 14-17.

Nikolayevskyy, V, Maurer, FP, Holicka, Y, Taylor, L, Liddy, H & Kranzer, K 2019, 'Novel external quality assurance scheme for drug susceptibility testing of non-tuberculous mycobacteria: a multicentre pilot study', JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, Jg. 74, Nr. 5, S. 1288-1294. https://doi.org/10.1093/jac/dkz027

Koushk-Jalali, B, Freitag, AP, Tigges, C, Oellig, F, Hillemann, D & Kreuter, A 2019, 'Sporotrichoid Fish Tank Granuloma', QJM : monthly journal of the Association of Physicians, Jg. 112, Nr. 2, S. 147. https://doi.org/10.1093/qjmed/hcy203

Andres, S, Gröschel, MI, Hillemann, D, Merker, M, Niemann, S & Kranzer, K 2019, 'A Diagnostic Algorithm To Investigate Pyrazinamide and Ethambutol Resistance in Rifampin-Resistant Mycobacterium tuberculosis Isolates in a Low-Incidence Setting', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 63, Nr. 2. https://doi.org/10.1128/AAC.01798-18

Houben, RMGJ, Lalli, M, Kranzer, K, Menzies, NA, Schumacher, SG & Dowdy, DW 2019, 'What if they don't have tuberculosis? The consequences and trade-offs involved in false-positive diagnoses of tuberculosis', CLINICAL INFECTIOUS DISEASES , Jg. 68, Nr. 1, S. 150-156. https://doi.org/10.1093/cid/ciy544

ESCMID generic competencies working group & Maurer, FP 2019, 'ESCMID generic competencies in antimicrobial prescribing and stewardship: towards a European consensus', CLINICAL MICROBIOLOGY AND INFECTION , Jg. 25, Nr. 1, S. 13-19. https://doi.org/10.1016/j.cmi.2018.09.022

 

2018

Walker, TM, Merker, M, Knoblauch, AM, Helbling, P, Schoch, OD, van der Werf, MJ, Kranzer, K, Fiebig, L, Kröger, S, Haas, W, Hoffmann, H, Indra, A, Egli, A, Cirillo, DM, Robert, J, Rogers, TR, Groenheit, R, Mengshoel, AT, Mathys, V, Haanperä, M, Soolingen, DV, Niemann, S, Böttger, EC, Keller, PM & MDR-TB Cluster Consortium 2018, 'A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study' Lancet Infectious Diseases, Jg. 18, Nr. 4, S. 431-440. DOI: 10.1016/S1473-3099(18)30004-5

Katchanov, J, Asar, L, Klupp, E-M, Both, A, Rothe, C, König, C, Rohde, H, Kluge, S & Maurer, FP 2018, 'Carbapenem-resistant Gram-negative pathogens in a German university medical center: Prevalence, clinical implications and the role of novel $-lactam/$-lactamase inhibitor combinations' PLOS ONE, Jg. 13, Nr. 4, S. e0195757.

Maurer, FP, Pohle, P, Kernbach, M, Sievert, D, Hillemann, D, Rupp, J, Hombach, M & Kranzer, K 2018, 'Differential drug susceptibility patterns of Mycobacterium chimaera and other members of the Mycobacterium avium-intracellulare complex' CLINICAL MICROBIOLOGY AND INFECTION . DOI: 10.1016/j.cmi.2018.06.010

Rukuni, R, McHugh, G, Majonga, E, Kranzer, K, Mujuru, H, Munyati, S, Nathoo, K, Gregson, CL, Kuper, H & Ferrand, RA 2018, 'Disability, Social Functioning and School Inclusion Among Older Children And Adolescents Living With HIV In Zimbabwe' Tropical medicine & international health, Jg. 23, Nr. 2, S. 149-155. DOI: 10.1111/tmi.13012

Schliemann, S, Rässler, F, Tittelbach, J, Kranzer, K, Zollmann, C & Elsner, P 2018, 'Disseminated Mycobacterium marinum skin infection due to chronic lymphedema in an immunocompetent patient' JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT , Jg. 16, Nr. 5, S. 614-616. DOI: 10.1111/ddg.13491

Schliemann, S, Räßler, F, Tittelbach, J, Kranzer, K, Zollmann, C & Elsner, P 2018, 'Disseminierte kutane Infektion mit Mycobacterium marinum bei chronischem Lymphödem bei einem immunkompetenten Patienten' JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT , Jg. 16, Nr. 5, S. 613-616. DOI: 10.1111/ddg.13491_g

Kranzer, K, Simms, V, Bandason, T, Dauya, E, McHugh, G, Munyati, S, Chonzi, P, Dakshina, S, Mujuru, H, Weiss, HA & Ferrand, RA 2018, 'Economic incentives for HIV testing by adolescents in Zimbabwe: a randomised controlled trial' Lancet HIV, Jg. 5, Nr. 2, S. e79-e86. DOI: 10.1016/S2352-3018(17)30176-5

Zallet, J, Olaru, ID, Witt, A-K, Vock, P, Kalsdorf, B, Andres, S, Hillemann, D & Kranzer, K 2018, 'Evaluation of OMNIgene•SPUTUM reagent for mycobacterial culture' INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Jg. 22, Nr. 8, S. 945-949. DOI: 10.5588/ijtld.17.0020

Deinhardt-Emmer, S, Höring, S, Mura, C, Hillemann, D, Hermann, B, Sachse, S, Bohnert, J & Löffler, B 2018, 'First Time Isolation of From a Respiratory Sample' Clinical medicine insights. Circulatory, respiratory and pulmonary medicine, Jg. 12, S. 1179548417747529. DOI: 10.1177/1179548417747529

Zignol, M, Cabibbe, AM, Dean, AS, Glaziou, P, Alikhanova, N, Ama, C, Andres, S, Barbova, A, Borbe-Reyes, A, Chin, DP, Cirillo, DM, Colvin, C, Dadu, A, Dreyer, A, Driesen, M, Gilpin, C, Hasan, R, Hasan, Z, Hoffner, S, Hussain, A, Ismail, N, Kamal, SMM, Khanzada, FM, Kimerling, M, Kohl, TA, Mansjö, M, Miotto, P, Mukadi, YD, Mvusi, L, Niemann, S, Omar, SV, Rigouts, L, Schito, M, Sela, I, Seyfaddinova, M, Skenders, G, Skrahina, A, Tahseen, S, Wells, WA, Zhurilo, A, Weyer, K, Floyd, K & Raviglione, MC 2018, 'Genetic sequencing for surveillance of drug resistance in tuberculosis in highly endemic countries: a multi-country population-based surveillance study' Lancet Infectious Diseases, Jg. 18, Nr. 6, S. 675-683. DOI: 10.1016/S1473-3099(18)30073-2

Desai, SR, Nair, A, Rylance, J, Mujuru, H, Nathoo, K, McHugh, G, Majonga, E, Metcalfe, J, Kranzer, K & Ferrand, RA 2018, 'HIV-Associated Chronic Lung Disease in Children and Adolescents in Zimbabwe: Chest Radiographic and High-Resolution Computed Tomography Findings' CLINICAL INFECTIOUS DISEASES , Jg. 66, Nr. 2, S. 274-281. DOI: 10.1093/cid/cix778

Pham, TH, Peter, J, Mello, FCQ, Parraga, T, Lan, NTN, Nabeta, P, Valli, E, Caceres, T, Dheda, K, Dorman, SE, Hillemann, D, Gray, CM & Perkins, MD 2018, 'Performance of the TB-LAMP diagnostic assay in reference laboratories: Results from a multicentre study' INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES , Jg. 68, S. 44-49. DOI: 10.1016/j.ijid.2018.01.005

Olaru, ID, Patel, H, Kranzer, K & Perera, N 2018, 'Turnaround time of whole genome sequencing for mycobacterial identification and drug susceptibility testing in routine practice' CLINICAL MICROBIOLOGY AND INFECTION , Jg. 24, Nr. 6, S. 659.e5-659.e7. DOI: 10.1016/j.cmi.2017.10.001

Hillemann, D, Haasis, C, Andres, S, Behn, T & Kranzer, K 2018, 'Validation of the FluoroType® MTBDR assay for the detection of rifampicin and isoniazid resistance in complex isolates' JOURNAL OF CLINICAL MICROBIOLOGY, Jg. 56, Nr. 6, pii:e00072-18. DOI: 10.1128/JCM.00072-18

Heyckendorf, J, Andres, S, Köser, CU, Olaru, ID, Schön, T, Sturegård, E, Beckert, P, Schleusener, V, Kohl, TA, Hillemann, D, Moradigaravand, D, Parkhill, J, Peacock, SJ, Niemann, S, Lange, C & Merker, M 2018, 'What is resistance? Impact of phenotypic versus molecular drug resistance testing on multi- and extensively drug-resistant tuberculosis therapy' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Jg. 62, Nr. 2, S. e01550-17. DOI: 10.1128/AAC.01550-17

 

2017

Fiebig, L, Kohl, TA, Popovici, O, Mühlenfeld, M, Indra, A, Homorodean, D, Chiotan, D, Richter, E, Rüsch-Gerdes, S, Schmidgruber, B, Beckert, P, Hauer, B, Niemann, S, Allerberger, F & Haas, W 2017, 'A joint cross-border investigation of a cluster of multidrug-resistant tuberculosis in Austria, Romania and Germany in 2014 using classic, genotyping and whole genome sequencing methods: lessons learned' Euro Surveillance, Bd 22, Nr. 2. DOI: 10.2807/1560-7917.ES.2017.22.2.30439

Havlicek, J, Rivera-Milla, E, Slickers, P, Andres, S, Feuerriegel, S, Niemann, S, Merker, M & Labugger, I 2017, 'An application of competitive reporter monitored amplification (CMA) for rapid detection of single nucleotide polymorphisms (SNPs)' PLOS ONE, Bd 12, Nr. 8, S. e0183561. DOI: 10.1371/journal.pone.0183561

Pedrazzoli, D, Lalli, M, Boccia, D, Houben, R & Kranzer, K 2017, 'Can tuberculosis patients in resource-constrained settings afford chest radiography?' The European respiratory journal, Bd 49, Nr. 3. DOI: 10.1183/13993003.01877-2016

Wilmore, SM, Kranzer, K, Williams, A, Makamure, B, Nhidza, AF, Mayini, J, Bandason, T, Metcalfe, J, Nicol, MP, Balakrishnan, I, Ellington, MJ, Woodford, N, Hopkins, S, McHugh, TD & Ferrand, RA 2017, 'Carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae in HIV-infected children in Zimbabwe' INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, Bd 66, Nr. 5, S. 609-615. DOI: 10.1099/jmm.0.000474

Khan, PY, Glynn, JR, Mzembe, T, Mulawa, D, Chiumya, R, Crampin, AC, Kranzer, K & Fielding, KL 2017, 'Challenges in the estimation of the annual risk of Mycobacterium tuberculosis infection in children aged under 5 years' International journal of epidemiology, Bd 186, Nr. 8, S. 1015-1022. DOI: 10.1093/aje/kwx153

McHugh, G, Simms, V, Dauya, E, Bandason, T, Chonzi, P, Metaxa, D, Munyati, S, Nathoo, K, Mujuru, H, Kranzer, K & Ferrand, RA 2017, 'Clinical outcomes in children and adolescents initiating antiretroviral therapy in decentralized healthcare settings in Zimbabwe' AIDS, Bd 20, Nr. 1, S. 21843. DOI: 10.7448/IAS.20.1.21843

Simms, V, Dauya, E, Dakshina, S, Bandason, T, McHugh, G, Munyati, S, Chonzi, P, Kranzer, K, Ncube, G, Masimirembwa, C, Thelingwani, R, Apollo, T, Hayes, R, Weiss, HA & Ferrand, RA 2017, 'Community burden of undiagnosed HIV infection among adolescents in Zimbabwe following primary healthcare-based provider-initiated HIV testing and counselling: A cross-sectional survey' PLoS medicine, Bd 14, Nr. 7, S. e1002360. DOI: 10.1371/journal.pmed.1002360

Lange, B, Khan, PY, Kalmambetova, G, Al-Darraji, HA, Alland, D, Antonenka, U, Brown, TJ, Balcells, ME, Blakemore, R, Denkinger, CM, Dheda, K, Hoffmann, H, Kadyrov, A, Lemaitre, N, Miller, MB, Nikolayevskyy, V, Ntinginya, NE, Ozkutuk, N, Palacios, JJ, Popowitch, EB, Porcel, JM, Teo, J, Theron, G & Kranzer, K 2017, 'Diagnostic accuracy of the Xpert(®) MTB/RIF cycle threshold level to predict smear positivity: a meta-analysis' INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Bd 21, Nr. 5, S. 493-502. DOI: 10.5588/ijtld.16.0702

Rukuni, R, McHugh, G, Majonga, E, Kranzer, K, Mujuru, H, Munyati, S, Nathoo, K, Gregson, CL, Kuper, H & Ferrand, RA 2017, 'Disability, Social Functioning and School Inclusion Among Older Children And Adolescents Living With HIV In Zimbabwe' Tropical medicine & international health. DOI: 10.1111/tmi.13012

Khan, PY, Crampin, AC, Mzembe, T, Koole, O, Fielding, KL, Kranzer, K & Glynn, JR 2017, 'Does antiretroviral treatment increase the infectiousness of smear-positive pulmonary tuberculosis?' INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Bd 21, Nr. 11, S. 1147-1154. DOI: 10.5588/ijtld.17.0162

Majonga, ED, Rehman, AM, McHugh, G, Mujuru, HA, Nathoo, K, Patel, MS, Munyati, S, Odland, JO, Kranzer, K, Kaski, JP & Ferrand, RA 2017, 'Echocardiographic reference ranges in older children and adolescents in sub-Saharan Africa' International journal of cardiology, Bd 248, S. 409-413. DOI: 10.1016/j.ijcard.2017.06.109

Kranzer, K, Simms, V, Bandason, T, Dauya, E, McHugh, G, Munyati, S, Chonzi, P, Dakshina, S, Mujuru, H, Weiss, HA & Ferrand, RA 2017, 'Economic incentives for HIV testing by adolescents in Zimbabwe: a randomised controlled trial' Lancet. DOI: 10.1016/S2352-3018(17)30176-5

Olaru, ID, McHugh, G, Dakshina, S, Majonga, E, Dauya, E, Bandason, T, Kranzer, K, Mujuru, H & Ferrand, RA 2017, 'False-negative HIV tests using oral fluid tests in children taking antiretroviral therapy from Harare, Zimbabwe' AIDS, Bd 20, Nr. Suppl 6, S. 21751. DOI: 10.7448/IAS.20.7.21751

van Ingen, J, Kohl, TA, Kranzer, K, Hasse, B, Keller, PM, Katarzyna Szafrańska, A, Hillemann, D, Chand, M, Schreiber, PW, Sommerstein, R, Berger, C, Genoni, M, Rüegg, C, Troillet, N, Widmer, AF, Becker, SL, Herrmann, M, Eckmanns, T, Haller, S, Höller, C, Debast, SB, Wolfhagen, MJ, Hopman, J, Kluytmans, J, Langelaar, M, Notermans, DW, Ten Oever, J, van den Barselaar, P, Vonk, ABA, Vos, MC, Ahmed, N, Brown, T, Crook, DW, Lamagni, T, Phin, N, Smith, EG, Zambon, M, Serr, A, Götting, T, Ebner, W, Thürmer, A, Utpatel, C, Spröer, C, Bunk, B, Nübel, U, Bloemberg, GV, Böttger, EC, Niemann, S, Wagner, D & Sax, H 2017, 'Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study' Lancet Infectious Diseases, Bd 17, Nr. 10, S. 1033-1041. DOI: 10.1016/S1473-3099(17)30324-9

Desai, SR, Nair, A, Rylance, J, Mujuru, H, Nathoo, K, McHugh, G, Majonga, E, Metcalfe, J, Kranzer, K & Ferrand, RA 2017, 'HIV-Associated Chronic Lung Disease in Children and Adolescents in Zimbabwe: Chest Radiographic and High-Resolution Computed Tomography Findings' CLINICAL INFECTIOUS DISEASES . DOI: 10.1093/cid/cix778

Hofmann-Thiel, S, Hoffmann, H, Hillemann, D, Rigouts, L, Van Deun, A & Kranzer, K 2017, 'How should discordance between molecular and growth-based assays for rifampicin resistance be investigated?' INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Bd 21, Nr. 7, S. 721-726. DOI: 10.5588/ijtld.17.0140

Chand, M, Lamagni, T, Kranzer, K, Hedge, J, Moore, G, Parks, S, Collins, S, Del Ojo Elias, C, Ahmed, N, Brown, T, Smith, EG, Hoffman, P, Kirwan, P, Mason, B, Smith-Palmer, A, Veal, P, Lalor, MK, Bennett, A, Walker, J, Yeap, A, Isidro Carrion Martin, A, Dolan, G, Bhatt, S, Skingsley, A, Charlett, A, Pearce, D, Russell, K, Kendall, S, Klein, AA, Robins, S, Schelenz, S, Newsholme, W, Thomas, S, Collyns, T, Davies, E, McMenamin, J, Doherty, L, Peto, TEA, Crook, DW, Zambon, M & Phin, N 2017, 'Insidious Risk of Severe Mycobacterium chimaera Infection in Cardiac Surgery Patients' CLINICAL INFECTIOUS DISEASES , Bd 64, Nr. 3, S. 335-342. DOI: 10.1093/cid/ciw754

Nakiwala, D, Kellgren, L, Herzmann, C, Olaru, ID, Brown, M, Ferrand, RA, Khan, P & Kranzer, K 2017, 'Language discordance between tuberculosis patients and healthcare providers challenging universal access' The European respiratory journal, Bd 49, Nr. 4. DOI: 10.1183/13993003.00116-2017

Kranzer, K, Bradley, J, Musaazi, J, Nyathi, M, Gunguwo, H, Ndebele, W, Dixon, M, Ndhlovu, M, Rehman, A, Khan, P, Vogt, F, Apollo, T & Ferrand, RA 2017, 'Loss to follow-up among children and adolescents growing up with HIV infection: age really matters' AIDS, Bd 20, Nr. 1, S. 1-7. DOI: 10.7448/IAS.20.1.21737

Gurbanova, E, Mehdiyev, R, Blondal, K, Tahirli, R, Mirzayev, F, Hillemann, D, Ismayilov, A & Altraja, A 2017, 'Mitigation of Discordant Rifampicin-Susceptibility Results Obtained by Xpert Mycobacterium tuberculosis/Rifampicin and Mycobacterium Growth Indicator Tube' Microbial Drug Resistance , Bd 23, Nr. 8, S. 1045-1052. DOI: 10.1089/mdr.2016.0149

Kodama, C, Lange, B, Olaru, ID, Khan, P, Lipman, M, Seddon, JA, Sloan, D, Grandjean, L, Ferrand, RA & Kranzer, K 2017, 'Mycobacterium tuberculosis transmission from patients with drug-resistant compared to drug-susceptible TB: a systematic review and meta-analysis' The European respiratory journal, Bd 50, Nr. 4. DOI: 10.1183/13993003.01044-2017

Herzmann, C, Golakov, M, Malekzada, F, Lonnroth, K & Kranzer, K 2017, 'Radiological screening of refugees in Germany' The European respiratory journal, Bd 49, Nr. 5. DOI: 10.1183/13993003.02487-2016

Vogt, F, Rehman, AM, Kranzer, K, Nyathi, M, Van Griensven, J, Dixon, M, Ndebele, W, Gunguwo, H, Colebunders, R, Ndlovu, M, Apollo, T & Ferrand, RA 2017, 'Relationship Between Time to Initiation of Antiretroviral Therapy and Treatment Outcomes: A Cohort Analysis of ART Eligible Adolescents in Zimbabwe' JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, Bd 74, Nr. 4, S. 390-398. DOI: 10.1097/QAI.0000000000001274

Nakatani, Y, Opel-Reading, HK, Merker, M, Machado, D, Andres, S, Kumar, SS, Moradigaravand, D, Coll, F, Perdigão, J, Portugal, I, Schön, T, Nair, D, Devi, KRU, Kohl, TA, Beckert, P, Clark, TG, Maphalala, G, Khumalo, D, Diel, R, Klaos, K, Aung, HL, Cook, GM, Parkhill, J, Peacock, SJ, Swaminathan, S, Viveiros, M, Niemann, S, Krause, KL & Köser, CU 2017, 'Role of alanine racemase mutations in Mycobacterium tuberculosis D-cycloserine resistance' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Bd 61, Nr. 12, e01575-14. DOI: 10.1128/AAC.01575-17

Feiterna-Sperling, C, Brinkmann, F, Adamczick, C, Ahrens, F, Barker, M, Berger, C, Berthold, LD, Bogyi, M, von Both, U, Frischer, T, Haas, W, Hartmann, P, Hillemann, D, Hirsch, FW, Kranzer, K, Kunitz, F, Maritz, E, Pizzulli, A, Ritz, N, Schlags, R, Spindler, T, Thee, S & Weizsäcker, K 2017, 'S2k-Leitlinie zur Diagnostik, Prävention und Therapie der Tuberkulose im Kindes- und Jugendalter' Pneumologie (Stuttgart, Germany), Bd 71, Nr. 10, S. 629-680. DOI: 10.1055/s-0043-116545

Marcus, R, Ferrand, RA, Kranzer, K & Bekker, L-G 2017, 'The case for viral load testing in adolescents in resource-limited settings' AIDS, Bd 20 Suppl 7. DOI: 10.1002/jia2.25002

Ferrand, RA, Simms, V, Dauya, E, Bandason, T, Mchugh, G, Mujuru, H, Chonzi, P, Busza, J, Kranzer, K, Munyati, S, Weiss, HA & Hayes, RJ 2017, 'The effect of community-based support for caregivers on the risk of virological failure in children and adolescents with HIV in Harare, Zimbabwe (ZENITH): an open-label, randomised controlled trial' The lancet child & adolescent health, Bd 1, Nr. 3, S. 175-183. DOI: 10.1016/S2352-4642(17)30051-2

Olaru, ID, Patel, H, Kranzer, K & Perera, N 2017, 'Turnaround time of whole genome sequencing for mycobacterial identification and drug susceptibility testing in routine practice' CLINICAL MICROBIOLOGY AND INFECTION . DOI: 10.1016/j.cmi.2017.10.001

Heyckendorf, J, Andres, S, Köser, CU, Olaru, ID, Schön, T, Sturegård, E, Beckert, P, Schleusener, V, Kohl, TA, Hillemann, D, Moradigaravand, D, Parkhill, J, Peacock, SJ, Niemann, S, Lange, C & Merker, M 2017, 'What is resistance?: Impact of phenotypic versus molecular drug resistance testing on multi- and extensively drug-resistant tuberculosis therapy' ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. DOI: 10.1128/AAC.01550-17