Central Group


  Mission    Projects    Funding    Techniques    Publications    Staff




Chen, J, Wang, X, Schmalen, A, Haines, S, Wolff, M, Ma, H, Zhang, H, Stoleriu, MG, Nowak, J, Nakayama, M, Bueno, M, Brands, J, Mora, AL, Lee, JS, Krauss-Etschmann, S, Dmitrieva, A, Frankenberger, M, Hofer, TP, Noessner, E, Moosmann, A, Behr, J, Milger, K, Deeg, CA, Staab-Weijnitz, CA, Hauck, SM, Adler, H, Goldmann, T, Gaede, KI, Behrends, J, Kammerl, IE & Meiners, S 2023, 'Antiviral CD8+ T cell immune responses are impaired by cigarette smoke and in COPD', The European respiratory journal, Jg. 62, Nr. 2, 2201374. https://doi.org/10.1183/13993003.01374-2022

GEN-COVID Multicenter Study Group 2023, 'CYP19A1 mediates severe SARS-CoV-2 disease outcome in males', Cell reports. Medicine, S. 101152. https://doi.org/10.1016/j.xcrm.2023.101152 



Shan, L, Zhang, L, Zhu, X, Wang, Z, Fang, S, Lin, J, Wang, J, Li, N, Liu, H, Zhang, X, Feng, Y, Liu, J, Pan, J, Ye, G, Yu, X, Tufman, A, Katalinic, A, Goldmann, T, Petersen, F, Jiang, J, Geng, G & Yu, X 2022, 'Chinese never smokers with adenocarcinoma of the lung are younger and have fewer lymph node metastases than smokers', RESPIRATORY RESEARCH, Jg. 23, Nr. 1, S. 293. https://doi.org/10.1186/s12931-022-02199-z

Kasper, B, Yue, X, Goldmann, T, Gülsen, A, Kugler, C, Yu, X & Petersen, F 2022, 'Air exposure and cell differentiation are essential for investigation of SARS-CoV-2 entry genes in human primary airway epithelial cells in vitro', Frontiers in Medicine, Jg. 9, S. 897695. https://doi.org/10.3389/fmed.2022.897695

DZIF-TB cohort study group 2022, 'Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes', The European respiratory journal, Jg. 60, Nr. 3. https://doi.org/10.1183/13993003.02263-2021

Kupsch, S, Eggers, LF, Spengler, D, Gisch, N, Goldmann, T, Fehrenbach, H, Stichtenoth, G, Krause, MF, Schwudke, D & Schromm, AB 2022, 'Characterization of phospholipid-modified lung surfactant in vitro and in a neonatal ARDS model reveals anti-inflammatory potential and surfactant lipidome signatures', European journal of pharmaceutical sciences, Jg. 175, S. 106216. https://doi.org/10.1016/j.ejps.2022.106216

Budczies, J, Kirchner, M, Kluck, K, Kazdal, D, Glade, J, Allgäuer, M, Kriegsmann, M, Heußel, C-P, Herth, FJ, Winter, H, Meister, M, Muley, T, Goldmann, T, Fröhling, S, Wermke, M, Waller, CF, Tufman, A, Reck, M, Peters, S, Schirmacher, P, Thomas, M, Christopoulos, P & Stenzinger, A 2022, 'Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma', CANCER IMMUNOLOGY IMMUNOTHERAPY, Jg. 71, Nr. 2, S. 251-265. https://doi.org/10.1007/s00262-021-02981-w

Uchino, J, Goldmann, T & Kimura, H 2022, 'Editorial: Treatment for Non-Small Cell Lung Cancer in Distinct Patient Populations', Frontiers in Oncology, S. 838570. https://doi.org/10.3389/fonc.2022.838570



Kirfel, J, Kümpers, CC, Fähnrich, A, Heidel, C, Jokic, M, Vlasic, I, Marwitz, S, Goldmann, T, Pasternack, H, Bohnet, S, Jonigk, D, Kühnel, MP, Offermann, A, Busch, H & Perner, S 2021, 'PD-L1 Dependent Immunogenic Landscape in Hot Lung Adenocarcinomas Identified by Transcriptome Analysis', Cancers, Jg. 13, Nr. 18. https://doi.org/10.3390/cancers13184562

Goldmann, T, Marwitz, S, Nitschkowski, D, Krupar, R, Backman, M, Elfving, H, Thurfjell, V, Lindberg, A, Brunnström, H, La Fleur, L, Mezheyeuski, A, Mattsson, JSM, Botling, J, Micke, P & Strell, C 2021, 'PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung', CANCER IMMUNOLOGY IMMUNOTHERAPY, Jg. 70, Nr. 9, S. 2577-2587. https://doi.org/10.1007/s00262-020-02825-z

Heyckendorf, J, Marwitz, S, Reimann, M, Avsar, K, DiNardo, A, Günther, G, Hoelscher, M, Ibraim, E, Kalsdorf, B, Kaufmann, SHE, Kontsevaya, I, van Leth, F, Mandalakas, AM, Maurer, FP, Müller, M, Nitschkowski, D, Olaru, ID, Popa, C, Rachow, A, Rolling, T, Rybniker, J, Salzer, HJF, Sanchez-Carballo, P, Schuhmann, M, Schaub, D, Spinu, V, Suárez, I, Terhalle, E, Unnewehr, M, Weiner, J, Goldmann, T & Lange, C 2021, 'Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model', The European respiratory journal, Jg. 58, Nr. 3. https://doi.org/10.1183/13993003.03492-2020

Brandenburg, J, Marwitz, S, Tazoll, SC, Waldow, F, Kalsdorf, B, Vierbuchen, T, Scholzen, T, Gross, A, Goldenbaum, S, Hölscher, A, Hein, M, Linnemann, L, Reimann, M, Kispert, A, Leitges, M, Rupp, J, Lange, C, Niemann, S, Behrends, J, Goldmann, T, Heine, H, Schaible, UE, Hölscher, C, Schwudke, D & Reiling, N 2021, 'WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis', Journal of Clinical Investigation, Jg. 131, Nr. 16, e141833. https://doi.org/10.1172/JCI141833

DZIF-TB cohort study group, Heyckendorf, J, Reimann, M, Marwitz, S & Lange, C 2021, 'Pathogen-free diagnosis of tuberculosis', Lancet Infectious Diseases, Jg. 21, Nr. 8, S. 1066. https://doi.org/10.1016/S1473-3099(21)00337-6

ALLIANCE Study Group, Abdo, M, Uddin, M, Goldmann, T, Marwitz, S, Bahmer, T, Holz, O, Kirsten, A-M, Trinkmann, F, von Mutius, E, Kopp, M, Hansen, G, Rabe, KF, Watz, H & Pedersen, F 2021, 'Raised sputum extracellular DNA confers lung function impairment and poor symptom control in an exacerbation-susceptible phenotype of neutrophilic asthma', RESPIRATORY RESEARCH, Jg. 22, S. 167. https://doi.org/10.1186/s12931-021-01759-z

Pasternack, H, Kuempers, C, Deng, M, Watermann, I, Olchers, T, Kuehnel, M, Jonigk, D, Kugler, C, Stellmacher, F, Goldmann, T, Kirfel, J, Ammerpohl, O, Perner, S & Reck, M 2021, 'Identification of molecular signatures associated with early relapse after complete resection of lung adenocarcinomas', Scientific Reports, Jg. 11, Nr. 1, S. 9532. https://doi.org/10.1038/s41598-021-89030-9

Glöckner, M, Marwitz, S, Rohmann, K, Watz, H, Nitschkowski, D, Rupp, J, Dalhoff, K, Goldmann, T & Drömann, D 2021, 'Haemophilus influenzae causes cellular trans-differentiation in human bronchial epithelia', INNATE IMMUNITY, Jg. 27, Nr. 3, S. 251-259. https://doi.org/10.1177/1753425921994906

Goldmann, T, Schmitt, B, Müller, J, Kröger, M, Scheufele, S, Marwitz, S, Nitschkowski, D, Schneider, MA, Meister, M, Muley, T, Thomas, M, Kugler, C, Rabe, KF, Siebert, R, Reck, M & Ammerpohl, O 2021, 'DNA methylation profiles of bronchoscopic biopsies for the diagnosis of lung cancer', Clinical epigenetics, Jg. 13, Nr. 1, S. 38. https://doi.org/10.1186/s13148-021-01024-6

Stellmacher, F, Kirfel, J, Kalsdorf, B, Maurer, FP, Perner, S & Goldmann, T 2021, 'Molekularpathologie der Tuberkulose: Stellenwert, Methodik und Grenzen', Der Pathologe, Jg. 42, Nr. 1, S. 78-82. https://doi.org/10.1007/s00292-021-00911-2

Goldmann, T, Hillemann, D, Maurer, F, Kalsdorf, B, Krupar, R, Stellmacher, F & Perner, S 2021, 'Mycobacterium szulgai als Posititivkontrolle zur Detektion von Kontaminationen beim Nachweis des Mycobacterium tuberculosis-Komplexes durch eine spezifische 16S-rDNA-PCR an FFPE-Material', Der Pathologe, Jg. 42, Nr. 1, S. 83-85. https://doi.org/10.1007/s00292-021-00912-1

Marwitz, S, Ballesteros-Merino, C, Jensen, SM, Reck, M, Kugler, C, Perner, S, Drömann, D, Goldmann, T & Fox, BA 2021, 'Phosphorylation of SMAD3 in immune cells predicts survival of patients with early stage non-small cell lung cancer', Journal for Immunotherapy of Cancer, Jg. 9, Nr. 2. https://doi.org/10.1136/jitc-2020-001469



Groth, EE, Weber, M, Bahmer, T, Pedersen, F, Kirsten, A, Börnigen, D, Rabe, KF, Watz, H, Ammerpohl, O & Goldmann, T 2020, 'Exploration of the sputum methylome and omics deconvolution by quadratic programming in molecular profiling of asthma and COPD: the road to sputum omics 2.0', RESPIRATORY RESEARCH, Jg. 21, Nr. 1, S. 274. https://doi.org/10.1186/s12931-020-01544-4

Liu, X, Tufman, A, Behr, J, Kiefl, R, Goldmann, T & Huber, RM 2020, 'Role of the erythropoietin receptor in Lung Cancer cells: erythropoietin exhibits angiogenic potential', Journal of Cancer, Jg. 11, Nr. 20, S. 6090-6100. https://doi.org/10.7150/jca.36924

Marwitz, S, Turkowski, K, Nitschkowski, D, Weigert, A, Brandenburg, J, Reiling, N, Thomas, M, Reck, M, Drömann, D, Seeger, W, Rabe, KF, Savai, R & Goldmann, T 2020, 'The Multi-Modal Effect of the Anti-fibrotic Drug Pirfenidone on NSCLC', Frontiers in Oncology, Jg. 9, S. 1550. https://doi.org/10.3389/fonc.2019.01550

Franzen, KF, Belkin, S, Goldmann, T, Reppel, M, Watz, H, Mortensen, K & Droemann, D 2020, 'The impact of heated tobacco products on arterial stiffness', Vascular medicine (London, England), Jg. 25, Nr. 6, S. 572-574. https://doi.org/10.1177/1358863X20943292



Wolff, M, El-Merhie, N, Reuter, S, Goldmann, T, Yildirim, AÖ, Fehrenbach, H & Krauss-Etschmann, S 2019, 'LSC - 2019 - Relevant murine model to study the development of COPD pathogenesis in smokers with viral infections', European respiratory journal proceedings, Jg. 54, Nr. 63. https://doi.org/10.1183/13993003.congress-2019.PA2408

Nitschkowski, D, Marwitz, S, Kotanidou, SA, Reck, M, Kugler, C, Rabe, KF, Ammerpohl, O & Goldmann, T 2019, 'Live and let die: epigenetic modifications of Survivin and Regucalcin in non-small cell lung cancer tissues contribute to malignancy', Clinical epigenetics, Jg. 11, Nr. 1, S. 157. https://doi.org/10.1186/s13148-019-0770-6

Lilis, I, Ntaliarda, G, Papaleonidopoulos, V, Giotopoulou, GA, Oplopoiou, M, Marazioti, A, Spella, M, Marwitz, S, Goldmann, T, Bravou, V, Giopanou, I & Stathopoulos, GT 2019, 'Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma', OncoImmunology, Jg. 8, Nr. 7, S. 1593802. https://doi.org/10.1080/2162402X.2019.1593802