Medizin

Pathologie des Universitätsklinikums Schleswig-Holstein, Campus Lübeck und des Leibniz-Forschungszentrums Borstel
Standort Borstel

Pathologie

Mission    Projekte    Drittmittel    Methoden    Publikationen    
Krankenversorgung    Diagnostik    Konsil- und Referenzzentrum für Pulmopathologie    Einsender    
Mitarbeiter/innen

Publikationen

2020

Becker, F, Joerg, V, Hupe, MC, Roth, D, Krupar, R, Lubczyk, V, Kuefer, R, Sailer, V, Duensing, S, Kirfel, J, Merseburger, AS, Brägelmann, J, Perner, S & Offermann, A 2020, 'Increased Mediator complex subunit CDK19 expression associates with aggressive prostate cancer', INTERNATIONAL JOURNAL OF CANCER , Jg. 146, Nr. 2, S. 577-588. https://doi.org/10.1002/ijc.32551

Hennenlotter, J, Neumann, T, Perner, S, Wagner, V, Stenzl, A, Todenhöfer, T & Rausch, S 2020, 'Impact of Histopathological Prostate Inflammation on Urine-Based Prostate Cancer Prediction Using the Prostate Cancer Gene 3 Score', Urologia internationalis, Jg. 104, Nr. 5-6, S. 483-488. https://doi.org/10.1159/000506885

Hupe, MC, Offermann, A, Tharun, L, Fürschke, A, Frydrychowicz, A, Garstka, N, Shariat, SF, Barkhausen, J, Merseburger, AS, Kramer, MW & Perner, S 2020, 'Histomorphological analysis of false positive PI-RADS 4 and 5 lesions', Urologic oncology, Jg. 38, Nr. 7, S. 636.e7-636.e12. https://doi.org/10.1016/j.urolonc.2020.01.017

Idel, C, Ribbat-Idel, J, Kuppler, P, Krupar, R, Offermann, A, Vogel, W, Rades, D, Kirfel, J, Wollenberg, B & Perner, S 2020, 'EVI1 as a Marker for Lymph Node Metastasis in HNSCC', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Jg. 21, Nr. 3. https://doi.org/10.3390/ijms21030854

Krupar, R, Watermann, C, Idel, C, Ribbat-Idel, J, Offermann, A, Pasternack, H, Kirfel, J, Sikora, AG & Perner, S 2020, 'In silico analysis reveals EP300 as a panCancer inhibitor of anti-tumor immune response via metabolic modulation', Scientific Reports, Jg. 10, Nr. 1, S. 9389. https://doi.org/10.1038/s41598-020-66329-7

Kuempers, C, van der Linde, LIS, Reischl, M, Vogel, W, Stellmacher, F, Reck, M, Heigener, D, Rabe, KF, Kirfel, J, Perner, S & Welker, L 2020, 'Comparison of PD-L1 expression between paired cytologic and histologic specimens from non-small cell lung cancer patients', Virchows Archiv : an international journal of pathology, Jg. 476, Nr. 2, S. 261-271. https://doi.org/10.1007/s00428-019-02632-7

Marwitz, S, Turkowski, K, Nitschkowski, D, Weigert, A, Brandenburg, J, Reiling, N, Thomas, M, Reck, M, Drömann, D, Seeger, W, Rabe, KF, Savai, R & Goldmann, T 2020, 'The Multi-Modal Effect of the Anti-fibrotic Drug Pirfenidone on NSCLC', Frontiers in Oncology, Jg. 9, S. 1550. https://doi.org/10.3389/fonc.2019.01550

Offermann, A, Hupe, MC, Joerg, V, Sailer, V, Kramer, MW, Merseburger, AS, Tharun, L & Perner, S 2020, 'Befundbericht zu Prostatastanzbiopsien – was Pathologen liefern und Urologen wollen', Der Urologe. Ausg. A, Jg. 59, Nr. 4, S. 461-468. https://doi.org/10.1007/s00120-020-01121-z

 

2019

Correa, W, Brandenburg, J, Behrends, J, Heinbockel, L, Reiling, N, Paulowski, L, Schwudke, D, Stephan, K, Martinez-de-Tejada, G, Brandenburg, K & Gutsmann, T 2019, 'Inactivation of Bacteria by γ-Irradiation to Investigate the Interaction with Antimicrobial Peptides', Biophysical journal, Jg. 117, Nr. 10, S. 1805-1819. https://doi.org/10.1016/j.bpj.2019.10.012

Fischer, AK, Pham, DL, Bösmüller, H, Lengerke, C, Wagner, P, Bachmann, C, Beschorner, C, Perner, S, Kommoss, S, Fend, F & Staebler, A 2019, 'Comprehensive in situ analysis of ALDH1 and SOX2 reveals increased expression of stem cell markers in high-grade serous carcinomas compared to low-grade serous carcinomas and atypical proliferative serous tumors', Virchows Archiv : an international journal of pathology, Jg. 475, Nr. 4, S. 479-488. https://doi.org/10.1007/s00428-019-02647-0

Gaisa, NT, Kristiansen, G & Perner, S 2019, 'Molekulares Tumorboard Uroonkologie aus pathologischer Sicht', Der Urologe. Ausg. A, Jg. 58, Nr. 7, S. 747-751. https://doi.org/10.1007/s00120-019-0934-1

Hupe, MC, Hoda, MR, Zengerling, F, Perner, S, Merseburger, AS & Cronauer, MV 2019, 'The BET-inhibitor PFI-1 diminishes AR/AR-V7 signaling in prostate cancer cells', World journal of Urology, Jg. 37, Nr. 2, S. 343-349. https://doi.org/10.1007/s00345-018-2382-8

Hupe, MC, Offermann, A, Sailer, V, Merseburger, AS & Perner, S 2019, 'Das neue ISUP 2014/WHO 2016 Prostatakarzinom-Grading – Status quo 5 Jahre nach seiner Einführung', Aktuelle Urologie, Jg. 50, Nr. 6, S. 619-624. https://doi.org/10.1055/a-0918-9473

Kümpers, C, Jokic, M, Haase, O, Offermann, A, Vogel, W, Grätz, V, Langan, EA, Perner, S & Terheyden, P 2019, 'Immune Cell Infiltration of the Primary Tumor, Not PD-L1 Status, Is Associated With Improved Response to Checkpoint Inhibition in Metastatic Melanoma', Frontiers in Medicine, Jg. 6, S. 27. https://doi.org/10.3389/fmed.2019.00027

Langan, EA, Kümpers, C, Graetz, V, Perner, S, Zillikens, D & Terheyden, P 2019, 'Intralesional interleukin-2: A novel option to maximize response to systemic immune checkpoint therapy in loco-regional metastatic melanoma', Dermatologic therapy, Jg. 32, Nr. 3, S. e12901. https://doi.org/10.1111/dth.12901

Lilis, I, Ntaliarda, G, Papaleonidopoulos, V, Giotopoulou, GA, Oplopoiou, M, Marazioti, A, Spella, M, Marwitz, S, Goldmann, T, Bravou, V, Giopanou, I & Stathopoulos, GT 2019, 'Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma', OncoImmunology, Jg. 8, Nr. 7, S. 1593802. https://doi.org/10.1080/2162402X.2019.1593802

Metzger, E, Wang, S, Urban, S, Willmann, D, Schmidt, A, Offermann, A, Allen, A, Sum, M, Obier, N, Cottard, F, Ulferts, S, Preca, B-T, Hermann, B, Maurer, J, Greschik, H, Hornung, V, Einsle, O, Perner, S, Imhof, A, Jung, M & Schüle, R 2019, 'KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells', Nature structural & molecular biology, Jg. 26, Nr. 5, S. 361-371. https://doi.org/10.1038/s41594-019-0219-9

Nitschkowski, D, Marwitz, S, Kotanidou, SA, Reck, M, Kugler, C, Rabe, KF, Ammerpohl, O & Goldmann, T 2019, 'Live and let die: epigenetic modifications of Survivin and Regucalcin in non-small cell lung cancer tissues contribute to malignancy', Clinical epigenetics, Jg. 11, Nr. 1, S. 157. https://doi.org/10.1186/s13148-019-0770-6

Offermann, A, Hupe, MC, Sailer, V, Merseburger, AS & Perner, S 2019, 'The new ISUP 2014/WHO 2016 prostate cancer grade group system: first résumé 5 years after introduction and systemic review of the literature', World journal of Urology, S. 1-6. https://doi.org/10.1007/s00345-019-02744-4

Offermann, A, Roth, D, Hupe, MC, Hohensteiner, S, Becker, F, Joerg, V, Carlsson, J, Kuempers, C, Ribbat-Idel, J, Tharun, L, Sailer, V, Kirfel, J, Svensson, M, Andren, O, Lubczyk, V, Kuefer, R, Merseburger, AS & Perner, S 2019, 'TRIM24 as an independent prognostic biomarker for prostate cancer', Urologic oncology, Jg. 37, Nr. 9, S. 576.e1-576.e10. https://doi.org/10.1016/j.urolonc.2019.05.006

Ortiz-Brüchle, N, Muders, M, Toma, M, Esposito, I, Hartmann, A, Stöhr, R, Reis, H, Wild, P, Köllermann, J, Bremmer, F, Leichsenring, J, Stenzinger, A, Merkelbach-Bruse, S, Kirfel, S, Perner, S, Hartmann, N, Roth, W, Jung, A, Kirchner, T, Schwamborn, K, Pfarr, N, Dahl, E, Knüchel, R & Gaisa, NT 2019, 'Status der Verfügbarkeit und Anwendung von „next generation sequencing“ (NGS) beim Harnblasenkarzinom – eine Umfrage in der Arbeitsgemeinschaft Uropathologie', Der Urologe. Ausg. A, S. 1-8. https://doi.org/10.1007/s00120-019-01046-2

Perner, S 2019, 'Bericht zur Sitzung der AG Kopf-Hals-Pathologie: 103. Jahrestagung der Deutschen Gesellschaft für Pathologie in Frankfurt am Main am 13.06.2019', Der Pathologe, Jg. 40, Nr. Suppl 3, S. 392. https://doi.org/10.1007/s00292-019-00646-1

Petrova, E, Zielinski, V, Bolm, L, Schreiber, C, Knief, J, Thorns, C, Bronsert, P, Timme-Bronsert, S, Bausch, D, Perner, S, Keck, T & Wellner, U 2019, 'Tumor budding as a prognostic factor in pancreatic ductal adenocarcinoma', Virchows Archiv : an international journal of pathology. https://doi.org/10.1007/s00428-019-02719-1

Pfalzgraff, A, Correa, W, Heinbockel, L, Schromm, AB, Lübow, C, Gisch, N, Martinez-de-Tejada, G, Brandenburg, K & Weindl, G 2019, 'LPS-neutralizing peptides reduce outer membrane vesicle-induced inflammatory responses', BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, Jg. 1864, Nr. 10, S. 1503-1513. https://doi.org/10.1016/j.bbalip.2019.05.018

Rades, D, Narvaez, CA, Splettstößer, L, Dömer, C, Setter, C, Idel, C, Ribbat-Idel, J, Perner, S, Bartscht, T, Olbrich, D, Schild, SE & Carl, J 2019, 'A randomized trial (RAREST-01) comparing Mepitel® Film and standard care for prevention of radiation dermatitis in patients irradiated for locally advanced squamous cell carcinoma of the head-and-neck (SCCHN)', Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, Jg. 139, S. 79-82. https://doi.org/10.1016/j.radonc.2019.07.023

Riabinska, A, Lehrmann, D, Jachimowicz, RD, Knittel, G, Fritz, C, Schmitt, A, Geyer, A, Heneweer, C, Wittersheim, M, Frenzel, LP, Torgovnick, A, Wiederstein, JL, Wunderlich, CM, Ortmann, M, Paillard, A, Wößmann, W, Borkhardt, A, Burdach, S, Hansmann, M-L, Rosenwald, A, Perner, S, Mall, G, Klapper, W, Merseburg, A, Krüger, M, Grüll, H, Persigehl, T, Wunderlich, FT, Peifer, M, Utermöhlen, O, Büttner, R, Beleggia, F & Reinhardt, HC 2019, 'ATM activity in T cells is critical for immune surveillance of lymphoma in vivo', LEUKEMIA. https://doi.org/10.1038/s41375-019-0618-2

 

2018

Capper, D, Engel, NW, Stichel, D, Lechner, M, Glöss, S, Schmid, S, Koelsche, C, Schrimpf, D, Niesen, J, Wefers, AK, Jones, DTW, Sill, M, Weigert, O, Ligon, KL, Olar, A, Koch, A, Forster, M, Moran, S, Tirado, OM, Sáinz-Japeado, M, Mora, J, Esteller, M, Alonso, J, Del Muro, XG, Paulus, W, Felsberg, J, Reifenberger, G, Glatzel, M, Frank, S, Monoranu, CM, Lund, VJ, von Deimling, A, Pfister, S, Buslei, R, Ribbat-Idel, J, Perner, S, Gudziol, V, Meinhardt, M & Schüller, U 2018, 'DNA methylation-based reclassification of olfactory neuroblastoma' Acta neuropathologica, Jg. 136, Nr. 2, S. 255-271. DOI: 10.1007/s00401-018-1854-7

Zhang, Y, Wang, X, Perner, S, Bánkfalvi, Á & Schlücker, S 2018, 'Effect of antigen retrieval methods on non-specific binding of anti-body-metal nanoparticle conjugates on FFPE tissue' ANALYTICAL CHEMISTRY , Jg. 10, S. 11. DOI: 10.1021/acs.analchem.7b03144

Tamò, L, Simillion, C, Hibaoui, Y, Feki, A, Gugger, M, Prasse, A, Jäger, B, Goldmann, T, Geiser, T & Gazdhar, A 2018, 'Gene Network Analysis of Interstitial Macrophages After Treatment with Induced Pluripotent Stem Cells Secretome (iPSC-cm) in the Bleomycin Injured Rat Lung' Stem cell reviews, Jg. 14, Nr. 3, S. 412-424. DOI: 10.1007/s12015-017-9790-9

Krupar, R, Hautmann, MG, Pathak, RR, Varier, I, McLaren, C, Gaag, D, Hellerbrand, C, Evert, M, Laban, S, Idel, C, Sandulache, V, Perner, S, Bosserhoff, AK & Sikora, AG 2018, 'Immuno-metabolic determinants of chemoradiotherapy response and survival in head and neck squamous cell carcinoma' AMERICAN JOURNAL OF PATHOLOGY, Jg. 188, Nr. 1, S. 72-83. DOI: 10.1016/j.ajpath.2017.09.013

Hupe, MC, Offermann, A, Perabo, F, Chandhasin, C, Perner, S, Merseburger, AS & Cronauer, MV 2018, 'Inhibitoren des Androgenrezeptor-N-Terminus’: Zielgerichtete Therapien gegen die Achillesferse verschiedener Androgenrezeptormoleküle im fortgeschrittenen Prostatakarzinom' Der Urologe. Ausg. A, Jg. 57, Nr. 2, S. 148-154. DOI: 10.1007/s00120-017-0541-y

Krupar, R, Schreiber, C, Offermann, A, Lengerke, C, Sikora, AG, Thorns, C & Perner, S 2018, 'In silico analysis of anti-leukemia immune response and immune evasion in acute myeloid leukemia' Leukemia & lymphoma, Jg. 12, S. 1-4. DOI: 10.1080/10428194.2018.1434883

George, J, Walter, V, Peifer, M, Alexandrov, LB, Seidel, D, Leenders, F, Maas, L, Müller, C, Dahmen, I, Delhomme, TM, Ardin, M, Leblay, N, Byrnes, G, Sun, R, De Reynies, A, McLeer-Florin, A, Bosco, G, Malchers, F, Menon, R, Altmüller, J, Becker, C, Nürnberg, P, Achter, V, Lang, U, Schneider, PM, Bogus, M, Soloway, MG, Wilkerson, MD, Cun, Y, McKay, JD, Moro-Sibilot, D, Brambilla, CG, Lantuejoul, S, Lemaitre, N, Soltermann, A, Weder, W, Tischler, V, Brustugun, OT, Lund-Iversen, M, Helland, Å, Solberg, S, Ansén, S, Wright, G, Solomon, B, Roz, L, Pastorino, U, Petersen, I, Clement, JH, Sänger, J & Perner, S 2018, 'Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors' Nature communications, Jg. 9, Nr. 1, S. 1048. DOI: 10.1038/s41467-018-03099-x

Jappe, U, Minge, S, Kreft, B, Ludwig, A, Przybilla, B, Walker, A, Varga, R, Seidel, P, Biedermann, T, Anemüller, W, Kromminga, A, Ruëff, F, Merk, H, Wagner, N, Treudler, R, Worm, M, Waldmann, I, Saloga, J, Becker, WM, Goldmann, T, Platts-Mills, TA & Homann, A 2018, 'Meat allergy associated with α-Gal - Closing diagnostic gaps by anti-α-Gal IgE immune profiling' ALLERGY, Jg. 73, Nr. 1, S. 93-105. DOI: 10.1111/all.13238

Yamada, N, Martin, LB, Zechendorf, E, Purvis, GSD, Chiazza, F, Varrone, B, Collino, M, Shepherd, J, Heinbockel, L, Gutsmann, T, Correa Vargas, WA, Brandenburg, K, Marx, G, Schuerholz, T, Brohi, K & Thiemermann, C 2018, 'Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock' American journal of surgical pathology, Jg. 268, Nr. 2, S. 348-356. DOI: 10.1097/SLA.0000000000002186

Chen, X, Bernemann, C, Tolkach, Y, Heller, M, Nientiedt, C, Falkenstein, M, Herpel, E, Jenzer, M, Grüllich, C, Jäger, D, Sültmann, H, Duensing, A, Perner, S, Cronauer, MV, Stephan, C, Debus, J, Schrader, AJ, Kristiansen, G, Hohenfellner, M & Duensing, S 2018, 'Overexpression of nuclear AR-V7 protein in primary prostate cancer is an independent negative prognostic marker in men with high-risk disease receiving adjuvant therapy' Urologic oncology, Jg. 36, Nr. 4, S. 161.e19-161.e30. DOI: 10.1016/j.urolonc.2017.11.001

Kuhlmann, N, Heinbockel, L, Correa, W, Gutsmann, T, Goldmann, T, Englisch, U & Brandenburg, K 2018, 'Peptide drug stability: The anti-inflammatory drugs Pep19-2.5 and Pep19-4LF in cream formulation' European journal of pharmaceutical sciences, Jg. 115, S. 240-247. DOI: 10.1016/j.ejps.2018.01.022

Heinemann, FG, Tolkach, Y, Deng, M, Schmidt, D, Perner, S, Kristiansen, G, Müller, SC & Ellinger, J 2018, 'Serum miR-122-5p and miR-206 expression: non-invasive prognostic biomarkers for renal cell carcinoma' Clinical epigenetics, Jg. 10, S. 11. DOI: 10.1186/s13148-018-0444-9

Vreka, M, Lilis, I, Papageorgopoulou, M, Giotopoulou, GA, Lianou, M, Giopanou, I, Kanellakis, NI, Spella, M, Agalioti, T, Armenis, V, Goldmann, T, Marwitz, S, Yull, FE, Blackwell, TS, Pasparakis, M, Marazioti, A & Stathopoulos, GT 2018, 'ΙκΒ kinase α is required for development and progression of KRAS-mutant lung adenocarcinoma' Cancer Research, Jg. 78, Nr. 11, S. 2939-2951. DOI: 10.1158/0008-5472.CAN-17-1944


2017

Schmitt, A, Knittel, G, Welcker, D, Yang, T-P, George, J, Nowak, M, Leeser, U, Buttner, R, Perner, S, Peifer, M & Reinhardt, HC 2017, 'ATM deficiency is associated with sensitivity to PARP1 and ATR inhibitors in lung adenocarcinoma' Cancer Research, Bd 77, Nr. 11, S. 3040-3056. DOI: 10.1158/0008-5472.CAN-16-3398

Marwitz, S & Goldmann, T 2017, 'Back into focus: tumour-associated macrophages and their role in immune checkpoint inhibition' Translational Cancer Research, Bd 6, Nr. supp6. DOI: 10.21037/tcr.2017.07.18

Schecher, S, Walter, B, Falkenstein, M, Macher-Goeppinger, S, Stenzel, P, Krümpelmann, K, Hadaschik, B, Perner, S, Kristiansen, G, Duensing, S, Roth, W & Tagscherer, KE 2017, 'Cyclin K dependent regulation of Aurora B affects apoptosis and proliferation by induction of mitotic catastrophe in prostate cancer' INTERNATIONAL JOURNAL OF CANCER , Bd 141, Nr. 8, S. 1643-1653. DOI: 10.1002/ijc.30864

Zhang, Y, Wang, X, Perner, S, Bánkfalvi, Á & Schlücker, S 2017, 'Effect of antigen retrieval methods on non-specific binding of anti-body-metal nanoparticle conjugates on FFPE tissue' ANALYTICAL CHEMISTRY . DOI: 10.1021/acs.analchem.7b03144

Watz, H, Uddin, M, Pedersen, F, Kirsten, A-M, Goldmann, T, Stellmacher, F, Groth, E, Larsson, B, Böttcher, G, Malmgren, A, Kraan, M & Rabe, KF 2017, 'Effects of the CXCR2 antagonist AZD5069 on lung neutrophil recruitment in asthma' PULMONARY PHARMACOLOGY & THERAPEUTICS , Bd 45, S. 121-123. DOI: 10.1016/j.pupt.2017.05.012

Deng, M, Brägelmann, J, Kryukov, I, Saraiva-Agostinho, N & Perner, S 2017, 'FirebrowseR: an R client to the Broad Institute's Firehose Pipeline' Database : the journal of biological databases and curation, Bd 2017, S. pii baw160. DOI: 10.1093/database/baw160

Ritter, M, Tamadaho, RS, Feid, J, Vogel, W, Wiszniewsky, K, Perner, S, Hoerauf, A & Layland, LE 2017, 'IL-4/5 signalling plays an important role during Litomosoides sigmodontis infection, influencing both immune system regulation and tissue pathology in the thoracic cavity' INTERNATIONAL JOURNAL FOR PARASITOLOGY, Bd 47, Nr. 14, S. 951-960. DOI: 10.1016/j.ijpara.2017.06.009

Laban, S, Giebel, G, Klümper, N, Schröck, A, Doescher, J, Spagnoli, G, Thierauf, J, Theodoraki, M-N, Remark, R, Gnjatic, S, Krupar, R, Sikora, AG, Litjens, G, Grabe, N, Kristiansen, G, Bootz, F, Schuler, PJ, Brunner, C, Brägelmann, J, Hoffmann, TK & Perner, S 2017, 'MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrencesimplications for immunotherapy' Oncotarget, Bd 8, Nr. 9, S. 14719-14735. DOI: 10.18632/oncotarget.14830

Offermann, A, Vlasic, I, Vogel, W, Ruiz, C, Zellweger, T, Rentsch, CA, Hagedorn, S, Behrends, J, Nowak, M, Merseburger, A, Bubendorf, L, Kirfel, J, Duensing, S, Shaikhibrahim, Z & Perner, S 2017, 'MED15 overexpression in prostate cancer arises during androgen deprivation therapy via PI3K/mTOR signaling' Oncotarget, Bd 8, Nr. 5, S. 7964-7976. DOI: 10.18632/oncotarget.13860

Klümper, N, Syring, I, Vogel, W, Schmidt, D, Müller, SC, Ellinger, J, Shaikhibrahim, Z, Brägelmann, J & Perner, S 2017, 'Mediator Complex Subunit MED1 Protein Expression Is Decreased during Bladder Cancer Progression' Frontiers in Medicine, Bd 4, Nr. 30. DOI: 10.3389/fmed.2017.00030

Kaufhold, I, Osbahr, S, Shima, K, Marwitz, S, Rohmann, K, Drömann, D, Goldmann, T, Dalhoff, K & Rupp, J 2017, 'Nontypeable Haemophilus influenzae (NTHi) directly interfere with the regulation of E-cadherin in lung epithelial cells' MICROBES AND INFECTION , Bd 19, Nr. 11, S. 560-566. DOI: 10.1016/j.micinf.2017.07.002

Brägelmann, J, Klümper, N, Offermann, A, von Mässenhausen, A, Böhm, D, Deng, M, Queisser, A, Sanders, C, Syring, I, Merseburger, AS, Vogel, W, Sievers, E, Vlasic, I, Carlsson, J, Andrén, O, Brossart, P, Duensing, S, Svensson, MA, Shaikhibrahim, Z, Kirfel, J & Perner, S 2017, 'Pan-cancer analysis of the Mediator complex transcriptome identifies CDK19 and CDK8 as therapeutic targets in advanced prostate cancer' CLINICAL CANCER RESEARCH , Bd 23, Nr. 7, S. 1829-1840. DOI: 10.1158/1078-0432.CCR-16-0094

Wang, H, Schaefer, T, Konantz, M, Braun, M, Varga, Z, Paczulla, AM, Reich, S, Jacob, F, Perner, S, Moch, H, Fehm, T, Kanz, L, Schulze-Osthoff, K & Lengerke, C 2017, 'Prominent oncogenic roles of EVI1 in breast carcinoma' Cancer Research, Bd 77, Nr. 8, S. 2148-2160. DOI: 10.1158/0008-5472.CAN-16-0593

von Klot, CA, Kuczyk, MA, Boeker, A, Reuter, C, Imkamp, F, Herrmann, TRW, Tezval, H, Kramer, MW, Perner, S & Merseburger, AS 2017, 'Role of free testosterone levels in patients with metastatic castration-resistant prostate cancer receiving second-line therapy' Oncology Letters, Bd 13, Nr. 1, S. 22-28. DOI: 10.3892/ol.2016.5392

Lautenschläger, I, Wong, YL, Sarau, J, Goldmann, T, Zitta, K, Albrecht, M, Frerichs, I, Weiler, N & Uhlig, S 2017, 'Signalling mechanisms in PAF-induced intestinal failure' Scientific Reports, Bd 7, Nr. 1, S. 13382. DOI: 10.1038/s41598-017-13850-x

Pfalzgraff, A, Heinbockel, L, Su, Q, Brandenburg, K & Weindl, G 2017, 'Synthetic anti-endotoxin peptides inhibit cytoplasmic LPS-mediated responses' BIOCHEMICAL PHARMACOLOGY , Bd 140, S. 64-72. DOI: 10.1016/j.bcp.2017.05.015

Müller, T, Fay, S, Vieira, RP, Karmouty-Quintana, H, Cicko, S, Ayata, K, Zissel, G, Goldmann, T, Lungarella, G, Ferrari, D, Di Virgilio, F, Robaye, B, Boeynaems, J-M, Blackburn, MR & Idzko, M 2017, 'The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease' Oncotarget, Bd 8, Nr. 22, S. 35962-35972. DOI: 10.18632/oncotarget.16414

 

2016

Affolter, A, Muller, M-F, Sommer, K, Stenzinger, A, Zaoui, K, Lorenz, K, Wolf, T, Sharma, S, Wolf, J, Perner, S, Weber, K-J, Freier, K, Plinkert, PK, Hess, J & Weichert, W 2016, 'Targeting irradiation-induced mitogen-activated protein kinase activation in vitro and in an ex vivo model for human head and neck cancer' Head and neck journal for the sciences and specialities of the head and neck, Bd 38 Suppl, Nr. 1, S. E2049-61. DOI: 10.1002/hed.24376

Biancosino, C, Krüger, M, Vollmer, E & Welker, L 2016, 'Intraoperative fine needle aspirations - diagnosis and typing of lung cancer in small biopsies: challenges and limitations' Diagnostic pathology, Bd 11, Nr. 1, S. 59. DOI: 10.1186/s13000-016-0510-6

Brandenburg, K, Heinbockel, L, Correa-Vargas, W & Lohner, K 2016, 'Peptides with dual mode of action: Killing bacteria and preventing endotoxin-induced sepsis' BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, Bd 1858, Nr. 5, S. 971-979. DOI: 10.1016/j.bbamem.2016.01.011

Brandenburg, K, Heinbockel, L, Correa-Vargas, W, Fukuoka, S, Gutsmann, T, Zähringer, U & Koch, MHJ 2016, 'Supramolecular structure of enterobacterial wild-type lipopolysaccharides (LPS), fractions thereof, and their neutralization by Pep19-2.5' Journal of Structural Biology, Bd 194, Nr. 1, S. 68-77. DOI: 10.1016/j.jsb.2016.01.014

Deng, M, Brägelmann, J, Schultze, JL & Perner, S 2016, 'Web-TCGA: an online platform for integrated analysis of molecular cancer data sets' BIOINFORMATICS , Bd 17, Nr. 1, S. 72. DOI: 10.1186/s12859-016-0917-9

Ganbat, D, Seehase, S, Richter, E, Vollmer, E, Reiling, N, Fellenberg, K, Gaede, KI, Kugler, C & Goldmann, T 2016, 'Mycobacteria infect different cell types in the human lung and cause species dependent cellular changes in infected cells' BMC PULMONARY MEDICINE, Bd 16, Nr. 1, S. 19. DOI: 10.1186/s12890-016-0185-5

Goldmann, T, Kugler, C, Reinmuth, N, Vollmer, E & Reck, M 2016, 'PD-L1 copy number gain in Non Small Cell Lung Cancer defines a new subset of patients for anti PD-L1 therapy' Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Bd 27, Nr. 1, S. 206-7. DOI: 10.1093/annonc/mdv510

Herrtwich, L, Nanda, I, Evangelou, K, Nikolova, T, Horn, V, [Unbekannt], S, Erny, D, Stefanowski, J, Rogell, L, Klein, C, Gharun, K, Follo, M, Seidl, M, Kremer, B, Münke, N, Senges, J, Fliegauf, M, Aschman, T, Pfeifer, D, Sarrazin, S, Sieweke, MH, Wagner, D, Dierks, C, Haaf, T, Ness, T, Zaiss, MM, Voll, RE, Deshmukh, SD, Prinz, M, Goldmann, T, Hölscher, C, Hauser, AE, Lopez-Contreras, AJ, Grün, D, Gorgoulis, V, Diefenbach, A, Henneke, P & Triantafyllopoulou, A 2016, 'DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas' CELL, Bd 167, Nr. 5, S. 1264. DOI: 10.1016/j.cell.2016.09.054

Hoefflin, R, Lahrmann, B, Warsow, G, Hübschmann, D, Spath, C, Walter, B, Chen, X, Hofer, L, Macher-Goeppinger, S, Tolstov, Y, Korzeniewski, N, Duensing, A, Grüllich, C, Jäger, D, Perner, S, Schönberg, G, Nyarangi-Dix, J, Isaac, S, Hatiboglu, G, Teber, D, Hadaschik, B, Pahernik, S, Roth, W, Eils, R, Schlesner, M, Sültmann, H, Hohenfellner, M, Grabe, N & Duensing, S 2016, 'Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity' Nature communications, Bd 7, S. ncomms11845. DOI: 10.1038/ncomms11845

Kraus, D, Reckenbeil, J, Perner, S, Winter, J & Probstmeier, R 2016, 'Expression Pattern of Matrix Metalloproteinase 20 (MMP20) in Human Tumors' Anticancer research, Bd 36, Nr. 6, S. 2713-8.

Luedeke, M, Rinckleb, AE, FitzGerald, LM, Geybels, MS, Schleutker, J, Eeles, RA, Teixeira, MR, Cannon-Albright, L, Ostrander, EA, Weikert, S, Herkommer, K, Wahlfors, T, Visakorpi, T, Leinonen, KA, Tammela, TLJ, Cooper, CS, Kote-Jarai, Z, Edwards, S, Goh, CL, McCarthy, F, Parker, C, Flohr, P, Paulo, P, Jerónimo, C, Henrique, R, Krause, H, Wach, S, Lieb, V, Rau, TT, Vogel, W, Kuefer, R, Hofer, MD, Perner, S, Rubin, MA, Agarwal, AM, Easton, DF, Amin Al Olama, A, Benlloch, S, Hoegel, J, Stanford, JL, Maier, C & PRACTICAL consortium 2016, 'Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status' HUMAN MOLECULAR GENETICS , Bd 25, Nr. 24, S. 5490-5499. DOI: 10.1093/hmg/ddw349

Malgorzata-Miller, G, Heinbockel, L, Brandenburg, K, van der Meer, JWM, Netea, MG & Joosten, LAB 2016, 'Bartonella quintana lipopolysaccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications' Scientific Reports, Bd 6, S. 34221. DOI: 10.1038/srep34221

Manrique-Moreno, M, Heinbockel, L, Suwalsky, M, Garidel, P & Brandenburg, K 2016, 'Biophysical study of the non-steroidal anti-inflammatory drugs (NSAID) ibuprofen, naproxen and diclofenac with phosphatidylserine bilayer membranes' Biochimica et biophysica acta, Bd 1858, Nr. 9, S. 2123-31. DOI: 10.1016/j.bbamem.2016.06.009

Martin, L, Peters, C, Heinbockel, L, Moellmann, J, Martincuks, A, Brandenburg, K, Lehrke, M, Müller-Newen, G, Marx, G & Schuerholz, T 2016, 'The synthetic antimicrobial peptide 19-2.5 attenuates mitochondrial dysfunction in cardiomyocytes stimulated with human sepsis serum' INNATE IMMUNITY, Bd 22, Nr. 8, S. 612-619. DOI: 10.1177/1753425916667474

Marwitz, S, Depner, S, Dvornikov, D, Merkle, R, Szczygiel, M, Müller-Decker, K, Lucarelli, P, Wäsch, M, Mairbäurl, H, Rabe, KF, Kugler, C, Vollmer, E, Reck, M, Scheufele, S, Kröger, M, Ammerpohl, O, Siebert, R, Goldmann, T & Klingmüller, U 2016, 'Downregulation of the TGF-β pseudoreceptor BAMBI in non-small cell lung cancer enhances TGF-β signaling and invasion' Cancer Research, Bd 76, Nr. 13, S. 3785-801. DOI: 10.1158/0008-5472.CAN-15-1326

Meder, L, König, K, Ozretić, L, Schultheis, AM, Ueckeroth, F, Ade, CP, Albus, K, Boehm, D, Rommerscheidt-Fuss, U, Florin, A, Buhl, T, Hartmann, W, Wolf, J, Merkelbach-Bruse, S, Eilers, M, Perner, S, Heukamp, LC & Buettner, R 2016, 'NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas' INTERNATIONAL JOURNAL OF CANCER , Bd 138, Nr. 4, S. 927-38. DOI: 10.1002/ijc.29835

Meller, S, VAN Ellen, A, Gevensleben, H, Bicker, A, Hankeln, T, Gorr, TA, Sailer, V, Dröge, F, Schröck, F, Bootz, F, Schröck, A, Perner, S, Dietrich, D & Kristiansen, G 2016, 'Ectopic Myoglobin Expression Is Associated with a Favourable Outcome in Head and Neck Squamous Cell Carcinoma Patients' Anticancer research, Bd 36, Nr. 12, S. 6235-6241. DOI: 10.21873/anticanres.11217

Merz, C, von Mässenhausen, A, Queisser, A, Vogel, W, Andrén, O, Kirfel, J, Duensing, S, Perner, S & Nowak, M 2016, 'IL-6 Overexpression in ERG-Positive Prostate Cancer Is Mediated by Prostaglandin Receptor EP2' AMERICAN JOURNAL OF PATHOLOGY, Bd 186, Nr. 4, S. 974-84. DOI: 10.1016/j.ajpath.2015.12.009

Metzger, E, Willmann, D, McMillan, J, Forne, I, Metzger, P, Gerhardt, S, Petroll, K, von Maessenhausen, A, Urban, S, Schott, A-K, Espejo, A, Eberlin, A, Wohlwend, D, Schüle, KM, Schleicher, M, Perner, S, Bedford, MT, Jung, M, Dengjel, J, Flaig, R, Imhof, A, Einsle, O & Schüle, R 2016, 'Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation' Nature structural & molecular biology, Bd 23, Nr. 2, S. 132-139. DOI: 10.1038/nsmb.3153

Nientiedt, M, Deng, M, Schmidt, D, Perner, S, Müller, SC & Ellinger, J 2016, 'Identification of aberrant tRNA-halves expression patterns in clear cell renal cell carcinoma' Scientific Reports, Bd 6, S. 37158. DOI: 10.1038/srep37158

Pfalzgraff, A, Heinbockel, L, Su, Q, Gutsmann, T, Brandenburg, K & Weindl, G 2016, 'Synthetic antimicrobial and LPS-neutralising peptides suppress inflammatory and immune responses in skin cells and promote keratinocyte migration' Scientific Reports, Bd 6, S. 31577. DOI: 10.1038/srep31577

Schnerch, J, Prasse, A, Vlachakis, D, Schuchardt, KL, Pechkovsky, DV, Goldmann, T, Gaede, KI, Müller-Quernheim, J & Zissel, G 2016, 'Functional TLR9 Expression and CXCR3 Ligand Release in Pulmonary Sarcoidosis' AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , Bd 55, Nr. 5, S. 749-757. DOI: 10.1165/rcmb.2015-0278OC

Schrödter, S, Braun, M, Syring, I, Klümper, N, Deng, M, Schmidt, D, Perner, S, Müller, SC & Ellinger, J 2016, 'Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma' LUNG CANCER, Bd 15, Nr. 1, S. 10. DOI: 10.1186/s12943-016-0495-5

Sommer, A, Kordowski, F, Büch, J, Maretzky, T, Evers, A, Andrä, J, Düsterhöft, S, Michalek, M, Lorenzen, I, Somasundaram, P, Tholey, A, Sönnichsen, FD, Kunzelmann, K, Heinbockel, L, Nehls, C, Gutsmann, T, Grötzinger, J, Bhakdi, S & Reiss, K 2016, 'Phosphatidylserine exposure is required for ADAM17 sheddase function' Nature communications, Bd 7, S. 11523. DOI: 10.1038/ncomms11523

Spier, I, Kerick, M, Drichel, D, Horpaopan, S, Altmüller, J, Laner, A, Holzapfel, S, Peters, S, Adam, R, Zhao, B, Becker, T, Lifton, RP, Holinski-Feder, E, Perner, S, Thiele, H, Nöthen, MM, Hoffmann, P, Timmermann, B, Schweiger, MR & Aretz, S 2016, 'Exome sequencing identifies potential novel candidate genes in patients with unexplained colorectal adenomatous polyposis' LUNG CANCER, Bd 15, Nr. 2, S. 281-8. DOI: 10.1007/s10689-016-9870-z

Spier, I, Drichel, D, Kerick, M, Kirfel, J, Horpaopan, S, Laner, A, Holzapfel, S, Peters, S, Adam, R, Zhao, B, Becker, T, Lifton, RP, Perner, S, Hoffmann, P, Kristiansen, G, Timmermann, B, Nöthen, MM, Holinski-Feder, E, Schweiger, MR & Aretz, S 2016, 'Low-level APC mutational mosaicism is the underlying cause in a substantial fraction of unexplained colorectal adenomatous polyposis cases' BMC medical genetics, Bd 53, Nr. 3, S. 172-9. DOI: 10.1136/jmedgenet-2015-103468

Syring, I, Klümper, N, Offermann, A, Braun, M, Deng, M, Boehm, D, Queisser, A, von Mässenhausen, A, Brägelmann, J, Vogel, W, Schmidt, D, Majores, M, Schindler, A, Kristiansen, G, Müller, SC, Ellinger, J, Shaikhibrahim, Z & Perner, S 2016, 'Comprehensive analysis of the transcriptional profile of the Mediator complex across human cancer types' Oncotarget, Bd 7, Nr. 17, S. 23043-55. DOI: 10.18632/oncotarget.8469

Ulmer, AJ, Kaconis, Y, Heinbockel, L, Correa, W, Alexander, C, Rietschel, ET, Mach, J-P, Gorczynski, RM, Heini, A, Rössle, M, Richter, W, Gutsmann, T & Brandenburg, K 2016, 'Enhancing actions of peptides derived from the γ-chain of fetal human hemoglobin on the immunostimulant activities of monophosphoryl lipid A' INNATE IMMUNITY, Bd 22, Nr. 3, S. 168-80. DOI: 10.1177/1753425916632304

von Mässenhausen, A, Deng, M, Billig, H, Queisser, A, Vogel, W, Kristiansen, G, Schröck, A, Bootz, F, Göke, F, Franzen, A, Heasley, L, Kirfel, J, Brägelmann, J & Perner, S 2016, 'Evaluation of FGFR3 as a Therapeutic Target in Head and Neck Squamous Cell Carcinoma' Targeted oncology. DOI: 10.1007/s11523-016-0431-z

von Mässenhausen, A, Sanders, C, Thewes, B, Deng, M, Queisser, A, Vogel, W, Kristiansen, G, Duensing, S, Schröck, A, Bootz, F, Brossart, P, Kirfel, J, Heasley, L, Brägelmann, J & Perner, S 2016, 'MERTK as a novel therapeutic target in head and neck cancer' Oncotarget. DOI: 10.18632/oncotarget.8724

von Mässenhausen, A, Sanders, C, Brägelmann, J, Konantz, M, Queisser, A, Vogel, W, Kristiansen, G, Duensing, S, Schröck, A, Bootz, F, Brossart, P, Kirfel, J, Lengerke, C & Perner, S 2016, 'Targeting DDR2 in Head and Neck Squamous Cell Carcinoma with Dasatinib' INTERNATIONAL JOURNAL OF CANCER . DOI: 10.1002/ijc.30279

von Mässenhausen, A, Brägelmann, J, Billig, H, Thewes, B, Queisser, A, Vogel, W, Kristiansen, G, Schröck, A, Bootz, F, Brossart, P, Kirfel, J & Perner, S 2016, 'Implication of the Receptor Tyrosine Kinase AXL in Head and Neck Cancer Progression' INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , Bd 18, Nr. 1. DOI: 10.3390/ijms18010007

Zhong, Q, Rüschoff, JH, Guo, T, Gabrani, M, Schüffler, PJ, Rechsteiner, M, Liu, Y, Fuchs, TJ, Rupp, NJ, Fankhauser, C, Buhmann, JM, Perner, S, Poyet, C, Blattner, M, Soldini, D, Moch, H, Rubin, MA, Noske, A, Rüschoff, J, Haffner, MC, Jochum, W & Wild, PJ 2016, 'Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity' Scientific Reports, Bd 6, S. 24146. DOI: 10.1038/srep24146

 

2015

Kriegsmann M, Muley T, Harms A, Tavernar L, Goldmann T, Dienemann H, Herpel E, Warth A. Differential diagnostic value of CD5 and CD117 expression in thoracic tumors: A large scale study of 1465 non-small cell lung cancer cases. Diagn Pathol. 2015 Dec 8;10(1):210. doi: 10.1186/s13000-015-0441-7.

Wagner C, Goldmann T, Rohmann K, Rupp J, Marwitz S, Rotta Detto Loria J, Limmer S, Zabel P, Dalhoff K, Drömann D. Budesonide Inhibits Intracellular Infection with Non-Typeable Haemophilus influenzae despite Its Anti-Inflammatory  Effects in Respiratory Cells and Human Lung Tissue: A Role for p38 MAP Kinase. Respiration. 2015 Nov;90(5):416-25. doi: 10.1159/000439226. Epub 2015 Oct 10.

Goldmann T, Kugler C, Reinmuth N, Vollmer E, Reck M. PD-L1 copy number gain in nonsmall-cell lung cancer defines a new subset of patients for anti PD-L1 therapy. Ann Oncol. 2015 Oct 20. pii: mdv510. [Epub ahead of print]

Martinez de Tejada G, Heinbockel L, Ferrer-Espada R, Heine H, Alexander C, Bárcena-Varela S, Goldmann T, Correa W, Wiesmüller KH, Gisch N, Sánchez-Gómez S, Fukuoka S, Schürholz T, Gutsmann T, Brandenburg K. Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides. Sci Rep. 2015 Sep 22;5:14292. doi: 10.1038/srep14292.

Pedersen F, Marwitz S, Holz O, Kirsten A, Bahmer T, Waschki B, Magnussen H, Rabe KF, Goldmann T, Uddin M, Watz H. Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients. Respir Med. 2015 Oct;109(10):1360-2. doi: 10.1016/j.rmed.2015.08.008. Epub 2015 Aug 22.

Zehethofer, N, Bermbach, S, Hagner, S, Garn, H, Müller, J, Goldmann, T, Lindner, B, Schwudke, D & König, P 2015, 'Lipid Analysis of Airway Epithelial Cells for Studying Respiratory Diseases' Chromatographia, Bd 78, Nr. 5-6, S. 403-413.

Pedersen, F, Holz, O, Lauer, G, Quintini, G, Kiwull-Schöne, H, Kirsten, A-M, Magnussen, H, Rabe, KF, Goldmann, T & Watz, H 2015, 'Multi-analyte profiling of inflammatory mediators in COPD sputum - The effects of processing' CYTOKINE , Bd 71, Nr. 2, S. 401-4.

Wong, YL, Lautenschläger, I, Dombrowsky, H, Zitta, K, Bein, B, Krause, T, Goldmann, T, Frerichs, I, Steinfath, M, Weiler, N & Albrecht, M 2015, 'Hydroxyethyl Starch (HES 130/0.4) Impairs Intestinal Barrier Integrity and Metabolic Function: Findings from a Mouse Model of the Isolated Perfused Small Intestine' PLOS ONE, Bd 10, Nr. 3, S. e0121497.

Lautenschläger, I, Frerichs, I, Dombrowsky, H, Sarau, J, Goldmann, T, Zitta, K, Albrecht, M, Weiler, N & Uhlig, S 2015, 'Quinidine, but not eicosanoid antagonists or dexamethasone, protect the gut from platelet activating factor-induced vasoconstriction, edema and paralysis' PLOS ONE, Bd 10, Nr. 3, S. e0120802.

Watermann, I, Schmitt, B, Stellmacher, F, Müller, J, Gaber, R, Kugler, C, Reinmuth, N, Huber, RM, Thomas, M, Zabel, P, Rabe, KF, Jonigk, D, Warth, A, Vollmer, E, Reck, M & Goldmann, T 2015, 'Improved diagnostics targeting c-MET in non-small cell lung cancer expression, amplification and activation?' Diagnostic pathology, Bd 10, Nr. 1, S. 130.

Heinbockel, L, Marwitz, S, Barcena Varela, S, Ferrer-Espada, R, Reiling, N, Goldmann, T, Gutsmann, T, Mier, W, Schürholz, T, Drömann, D, Brandenburg, K & Martinez de Tejada, G 2015, 'Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis' PLOS ONE, Bd 10, Nr. 7, S. e0133291.

2014

Shevchuk, O, Abidi, N, Klawonn, F, Wissing, J, Nimtz, M, Kugler, C, Steinert, M, Goldmann, T & Jänsch, L 2014, 'HOPE-Fixation of Lung Tissue Allows Retrospective Proteome and Phosphoproteome Studies' JOURNAL OF PROTEOME RESEARCH , Bd 13, Nr. 11, S. 5230.9.

Gaber, R, Watermann, I, Kugler, C, Reinmuth, N, Huber, RM, Schnabel, PA, Vollmer, E, Reck, M & Goldmann, T 2014, 'Correlation of EGFR expression, gene copy number and clinicopathological status in NSCLC' Diagnostic pathology, Bd 9, Nr. 1, S. 165.

Roessler, FC, Teichert, A, Ohlrich, M, Marxsen, JH, Stellmacher, F, Tanislav, C & Seidel, G 2014, 'Development of a new clot formation protocol for standardized in vitro investigations of sonothrombolysis' JOURNAL OF NEUROSCIENCE METHODS, Bd 237C, S. 26-32.

Reinmuth, N, Heigener, D, Goldmann, T, Watermann, I & Reck, M 2014, 'Reduzierte Dosis von TKI führt nicht zu Wirkungsverlust bei Patienten mit aktivierender EGFR-Mutation' Pneumologie (Stuttgart, Germany), Bd 68, Nr. 9, S. 619-23.

Marwitz, S, Kolarova, J, Reck, M, Reinmuth, N, Kugler, C, Schädlich, I, Haake, A, Zabel, P, Vollmer, E, Siebert, R, Goldmann, T & Ammerpohl, O 2014, 'The tissue is the issue improved methylome analysis from paraffin-embedded tissues by application of the HOPE technique' LABORATORY INVESTIGATION , Bd 94, Nr. 8, S. 927-33.

Bermbach, S, Weinhold, K, Roeder, T, Petersen, F, Kugler, C, Goldmann, T, Rupp, J & König, P 2014, 'Mechanisms of Cilia-Driven Transport in the Airways in the Absence of Mucus' AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , Bd 51, Nr. 1, S. 56-67.

Lang, DS, Marwitz, S, Heilenkötter, U, Schumm, W, Behrens, O, Simon, R, Reck, M, Vollmer, E & Goldmann, T 2014, 'Transforming Growth Factor-Beta Signaling Leads to uPA/PAI-1 Activation and Metastasis: A Study on Human Breast Cancer Tissues' PATHOLOGY & ONCOLOGY RESEARCH , Bd 20, Nr. 3, S. 727-732.

Lauenstein, L, Switalla, S, Prenzler, F, Seehase, S, Pfennig, O, Förster, C, Fieguth, H-G, Braun, A & Sewald, K 2014, 'Assessment of immunotoxicity induced by chemicals in human precision-cut lung slices (PCLS)' Toxicology In Vitro, Nr. 28(4), S. 588-99.

Petersen, A, Rennert, S, Kull, S, Becker, W-M, Notbohm, H, Goldmann, T & Jappe, U 2014, 'Roasting and lipid binding provide allergenic and proteolytic stability to the peanut allergen Ara h 8' Biological chemistry, Bd 395, Nr. 2, S. 239-50.

Jäger, J, Marwitz, S, Tiefenau, J, Rasch, J, Shevchuk, O, Kugler, C, Goldmann, T & Steinert, M 2014, 'Human lung tissue explants reveal novel interactions during Legionella pneumophila infections' INFECTION AND IMMUNITY , Bd 82, Nr. 1, S. 275-285.

Lang, D, Marwitz, S, Kugler, C, Reinmuth, N, Vollmer, E, Zabel, P, Reck, M & Goldmann, T 2014, 'Double Homeobox Protein DUX 4 in the Human Lung: Expression under Normal and Pathological Conditions' Global Journal of Pathology and Microbiology , Bd 2, DOI: dx.doi.org/10.14205/2310-8703.2014.02.01.1, S. 1-9.

 

2013

Goldmann T, Vollmer E. Comment on Nietner et al. [Virchows Arch (s2012) 461:259-269]. Virchows Arch. 2013 Jul 20. [Epub ahead of print]

Goldmann T, Pedersen F, Seehase S, Marwitz S, Lang DS, Kirsten AM, Zabel P, Vollmer E, Magnussen H, Rabe KF, Watz H. The Effect of Dithiothreitol on the Transcriptome of Induced Sputum Cells. Respiration. 2013 Apr 9. [Epub ahead of print]

van Bremen T, Drömann D, Luitjens K, Dodt C, Dalhoff K, Goldmann T, Schaaf B.  Triggering receptor expressed on myeloid cells-1 (Trem-1) on blood neutrophils is associated with cytokine inducibility in human E. coli sepsis. Diagn Pathol. 2013 Feb 15;8:24.

Lang DS, Heilenkötter U, Schumm W, Behrens O, Simon R, Vollmer E, Goldmann T.  Optimized immunohistochemistry in combination with image analysis: A reliable alternative to quantitative ELISA determination of uPA and PAI-1 for routine risk group discrimination in breast cancer. Breast. 2013 Oct;22(5):736-43.

Heinbockel L, Sánchez-Gómez S, Martinez de Tejada G, Dömming S, Brandenburg J, Kaconis Y, Hornef M, Dupont A, Marwitz S, Goldmann T, Ernst M, Gutsmann T, Schürholz T, Brandenburg K. Preclinical investigations reveal the broad-spectrum  neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors. Antimicrob Agents Chemother. 2013 Mar;57(3):1480-7.

Pedersen F, Marwitz S, Seehase S, Kirsten AM, Zabel P, Vollmer E, Rabe KF, Magnussen H, Watz H, Goldmann T. HOPE-preservation of paraffin-embedded sputum samples--a new way of bioprofiling in COPD. Respir Med. 2013 Apr;107(4):587-95.

Rotta detto Loria J, Rohmann K, Droemann D, Kujath P, Rupp J, Goldmann T, Dalhoff K.
Nontypeable Haemophilus influenzae activates the NLRP3 inflammasome and leads to caspase-1-dependent secretion of Interleukin-1 - a possible pathway of exacerbations in COPD. 2013 PlosOne 8(6): e66818. Open Access

 

2012

Fischer A, Schmid B, Ellinghaus D, Nothnagel M, Gaede KI, Schurmann M, Lipinski S, Rosenstiel P, Zissel G, Hohne K, Petrek M, Kolek V, Pabst S, Grohe C, Grunewald J, Ronninger M, Eklund A, Padyukov L, Gieger C, Wichmann H-E, Nebel A, Franke A, Muller-Quernheim J, Hofmann S, Schreiber S. A Novel Sarcoidosis Risk Locus for Europeans on Chromosome 11q13.1. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2012 Nov;186(9):877–885.

Abdullah M, Goldmann T. Pulmonary haptoglobin (pHp) is part of the surfactant system in the human lung. DIAGNOSTIC PATHOLOGY 2012 Nov;7(1):158. Open Access

Hattar K, Savai R, Subtil FSB, Wilhelm J, Schmall A, Lang DS, Goldmann T, Eul B, Dahlem G, Fink L, Schermuly R-T, Banat G-A, Sibelius U, Grimminger F, Vollmer E, Seeger W, Grandel U. Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation. CANCER IMMUNOLOGY AND IMMUNOTHERAPY 2012 Aug (in press). Open Access

Hofmann S, Fischer A, Nothnagel M, Jacobs G, Schmid B, Wittig M, Franke A, Gaede KI, Schürmann M, Petrek M, Mrazek F, Pabst S, Grohé C, Grunewald J, Ronninger M, Eklund A, Rosenstiel P, Höhne K, Zissel G, Müller-Quernheim J, Schreiber S. Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis. EUROPEAN RESPIRATORY JOURNAL 2012 Aug (in press).

Seidler A, Euler U, Muller-Quernheim J, Gaede KI, Latza U, Groneberg D, Letzel S. Systematic review: progression of beryllium sensitization to chronic beryllium disease. OCCUPATIONAL MEDICINE 2012 Jun;62(7):506–513.

Bang C, Schilhabel A, Weidenbach K, Kopp A, Goldmann T, Gutsmann T, Schmitz RA. Effects of Antimicrobial Peptides on Methanogenic Archaea. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2012 May;56(8):4123–4130.

On behalf of the Pulmonary Pathology Working Group of the German Society of Pathology, Warth A, Cortis J, Fink L, Fisseler-Eckhoff A, Geddert H, Hager T, Junker K, Kayser G, Kitz J, Länger F, Morresi-Hauf A, Ott G, Petersen I, Stenzinger A, Soltermann A, Ting S, Tischler V, Vollmer E, Schnabel PA, Weichert W. Training increases concordance in classifying pulmonary adenocarcinomas according to the novel IASLC/ATS/ERS classification. VIRCHOWS ARCHIV 2012 Jun;461(2):185–193.

Müller-Fielitz H, Lau M, Jöhren O, Stellmacher F, Schwaninger M, Raasch W. Blood Pressure Response to Angiotensin II is Enhanced in Obese Zucker Rats and is Attributed to an Aldosterone-Dependent Mechanism. BRITISH JOURNAL OF PHARMACOLOGY 2012 Aug;166(8):2417–29.

Goldmann T, Kähler D, Vollmer E. Proteomics? ARCHIVES OF PATHOLOGY AND LABORATORY MEDICINE 2012 Mar;136(3):236–237; author reply 237.

Abdullah M, Kähler D, Vock C, Reiling N, Kugler C, Dromann D, Rupp J, Hauber HP, Fehrenbach H, Zabel P, Vollmer E, Dalhoff K, Goldmann T. Pulmonary haptoglobin and CD163 are functional immunoregulatory elements in the human lung. RESPIRATION 2012 Jan;83(1):61-73.

 

2011

Hofmann S, Fischer A, Till A, Muller-Quernheim J, Hasler R, Franke A, Gäde KI, Schaarschmidt H, Rosenstiel P, Nebel A, Schurmann M, Nothnagel M, Schreiber S, the GenPhenReSa Consortium. A genome-wide association study reveals evidence of association with sarcoidosis at 6p12.1. EUROPEAN RESPIRATORY JOURNAL 2011 Nov;38(5):1127-1135.

Schultz H, Marwitz S, Baron-Lühr B, Zissel G, Kugler C, Rabe KF, Zabel P, Vollmer E, Gerdes J, Goldmann T. Generation and evaluation of a monoclonal antibody, designated MAdL, as a new specific marker for adenocarcinomas of the lung. BRITISH JORNAL OF CANCER 2011 Aug;105(5):673-81.

Roessler FC, Ohlrich M, Marxsen JH, Stellmacher F, Sprenger A, Dempfle C-E, Seidel G. The platelet-rich plasma clot: a standardized in-vitro clot formation protocol for investigations of sonothrombolysis under physiological flows. BLOOD COAGULATION & FIBRINOLYSIS 2011 Jul;22(5):407-15.

Marwitz S, Abdullah M, Vock C, Fine JS, Visvanathan S, Gaede K, Hauber HP, Zabel P, Goldmann T. HOPE-BAL: Improved Molecular Diagnostics by Application of a Novel Technique for Fixation and Paraffin-Embedding. JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2011 Jun;59(6):601-14. Epub 2011 Mar 23.

Andresen E, Lange C, Strodthoff D, Goldmann T, Fischer N, Sahly H, Branscheid D, Heine H. S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection. BMC PULMONARY MEDICINE 2011;11:10. (Open Access)

Goldmann, T, Neitemeier, H. A definition of time by relation of energy and mass. HYPOTHESIS. 2011;9(1) Available from: http://hypothesisjournal.com/index.php/main/article/view/199 (Open Access)

Zweytick D, Deutsch G, Andrä J, Blondelle SE, Vollmer E, Jerala R, Lohner K. Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2011 Jun;286(24):21266-21276.

Sprenger L, Goldmann T, Vollmer E, Steffen A, Wollenberg B, Zabel P, Hauber H-P. Dexamethasone and N-acetyl-cysteine attenuate Pseudomonas aeruginosa-induced mucus expression in human airways. PULMONARY PHARMACOLOGY & THERAPEUTICS 2011 Apr;24(2):232-239 Epub Dec 2010.

Vollmer E, Goldmann T. Pathology on the edge of interdisciplinarity. A historical epitome. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2011;52(1 Suppl):223-230.

Andra J, Goldmann T, Ernst CM, Peschel A, Gutsmann T. Multiple peptide resistance factor (MPRF)-mediated resistance of staphylococcus aureus against antimicrobial peptides coincides with a modulated peptide interaction with artificial membranes comprising lysyl-phosphatidylglycerol. JOURNAL OF BIOLOGICAL CHEMISTRY 2011 May 27;286(21):18692-700.

Roessler FC, Ohlrich M, Marxsen JH, Schmieger M, Weber P-K, Stellmacher F, Trillenberg P, Eggers J, Seidel G. Introduction of a new model for time-continuous and non-contact investigations of in-vitro thrombolysis under physiological flow conditions. BMC NEUROLOGY 2011;11:58. (Open Access)

Kayser K, Borkenfeld S, Goldmann T, Kayser G. To be at the right place at the right time. DIAGNOSTIC PATHOLOGY 2011;6:68. (Open Access)

Rohmann K, Tschernig T, Pabst R, Goldmann T, Drömann D. Innate immunity in the human lung: pathogen recognition and lung disease. CELL AND TISSUE RESEARCH 2011 Jan;343(1):167-174.

Abdullah M, Marwitz S, Kähler D, Schultz H, Kugler C, Zabel P, Vollmer E, Goldmann T. Pulmonary haptoglobin: a new marker for adenocarcinomas of the lung? PATHOLOGY 2011 Jan;43(1):70-72.

 

2010

Müller A, Goldmann T, Seitzer U. Measuring Immune Responses In Situ: Immunofluorescent and Immunoenzymatic Techniques. In: Immunology of Infection (METHODS IN MICROBIOLOGY ; 37). Academic Press; 2010 p. 421-437.

Radtke J, Rezaie SG, Kugler C, Zabel P, Schultz H, Vollmer E, Goldmann T, Lang DS. Expression analysis of EML4 in normal lung tissue and non-small cell lung cancer (NSCLC) in the absence and presence of chemotherapeutics. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2010;51(4):647-653.

Vollmer E, Schultz H, Stellmacher F, Kähler D, Abdullah M, Galle J, Lang DS, Goldmann T. Tumors in the lung - morphologic features and the challenge of integrating biomarker signatures into diagnostics. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY = REVUE ROUMAINE DE MORPHOLOGIE ET EMBRYOLOGIE 2010;51(4):607-614.

Orinska Z, Föger N, Huber M, Marschall J, Mirghomizadeh F, Du X, Scheller M, Rosenstiel P, Goldmann T, Bollinger A, Beutler BA, Bulfone-Paus S. I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development. BLOOD 2010 Oct;116(15):2665-2675.

Dromann D, Rupp J, Rohmann K, Osbahr S, Ulmer AJ, Marwitz S, Roschmann K, Abdullah M, Schultz H, Vollmer E, Zabel P, Dalhoff K, Goldmann T. The TGF-beta-Pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae. RESPIRATORY RESEARCH 2010 May;11(1):67. Open Access

Hammer MU, Brauser A, Olak C, Brezesinski G, Goldmann T, Gutsmann T, Andrä J. Lipopolysaccharide interaction is decisive for the activity of the antimicrobial peptide NK-2 against Escherichia coli and Proteus mirabilis. BIOCHEMICAL JOURNAL 2010 May;427(3):477-488.

Kahler D, Alexander C, Schultz H, Abdullah M, Branscheid D, Lindner B, Zabel P, Vollmer E, Goldmann T. Proteomics Out of the Archive: Two-dimensional Electrophoresis and Mass Spectrometry Using HOPE-fixed, Paraffin-embedded Tissues. JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2010 Mar;58(3):221-228.

Sayk F, Mahnken A, Stellmacher F, Dalhoff K, Merz H. Cancer-to-cancer metastasis: amelanotic melanoma into renal cell carcinoma. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT 2010 Mar;135(11):507-510.

Lautenschlager I, Dombrowsky H, Frerichs I, Kuchenbecker S, Bade S, Schultz H, Zabel P, Scholz J, Weiler N, Uhlig S. A model of the isolated perfused rat small intestine. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 2010 Feb;298(2):G304-G313.

Schmengler K, Goldmann T, Brade L, Sánchez Carballo PM, Albrecht S, Brade H, Kosma P, Sahly H, Hauber H, Länger F, Meyer R, Welte T, Zähringer U. Monoclonal antibody S60-4-14 reveals diagnostic potential in the identification of Pseudomonas aeruginosa in lung tissues of cystic fibrosis patients. EUROPEAN JOURNAL OF CELL BIOLOGY 2010;89(1):25-33.

Hauber H, Karp D, Goldmann T, Vollmer E, Zabel P. Effect of low tidal volume ventilation on lung function and inflammation in mice. BMC PULMONARY MEDICINE 2010;10(1):21. Open Access

Hauber H, Karp D, Goldmann T, Vollmer E, Zabel P. Comparison of the effect of lps and pam3 on ventilated lungs. BMC PULMONARY MEDICINE 2010;10(1):20. Open Access