Programmbereich Infektionen

Mikrobielle Grenzflächenbiologie

Mission    Projekte    Drittmittel    Methoden    Publikationen    Mitarbeiter/innen

Publikationen von 2011 bis 2002

2011

Uciechowski P, Imhoff H, Lange C, Meyer CG, Browne EN, Kirsten DK, Schröder AK, Schaaf B, Al-Lahham A, Reinert RR, Reiling N, Haase H, Hatzmann A, Fleischer D, Heussen N, Kleines M, Rink L. Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression. J. Leukoc. Biol. 2011 Aug;90(2):377-388.

Klug K, Ehlers S, Uhlig S, Reiling N. Mitogen-activated protein kinases p38 and ERK1/2 regulated control of Mycobacterium avium replication in primary murine macrophages is independent of tumor necrosis factor-alpha and interleukin-10. INNATE IMMUNITY 2011 Aug;17(5):470-85.

Schaale K, Neumann J, Schneider D, Ehlers S, Reiling N. Wnt signaling in macrophages: Augmenting and inhibiting mycobacteria-induced inflammatory responses. EUROPEAN JOURNAL OF CELL BIOLOGY 2011 Jun;90(6-7):553-9.

 

2010

Ungefroren H, Groth S, Hyder A, Thomsen N, Hinz H, Reiling N, Grage-Griebenow E, Held-Feindt J, Schulze M, Nüssler AK, Fändrich F. The generation of programmable cells of monocytic origin (PCMOs) involves partial repression of monocyte/macrophage markers and reactivation of pluripotency genes. STEM CELLS AND DEVELOPMENT 2010 Nov;19(11):1769-80.

Neumann J, Schaale K, Farhat K, Endermann T, Ulmer AJ, Ehlers S, Reiling N. Frizzled1 is a marker of inflammatory macrophages, and its ligand Wnt3a is involved in reprogramming Mycobacterium tuberculosis-infected macrophages. FASEB JOURNAL 2010 Nov;24(11):4599-4612.

Schromm AB, Reiling N, Howe J, Wiesmuller K, Roessle M, Brandenburg K. Influence of serum on the immune recognition of a synthetic lipopeptide mimetic of the 19-kDa lipoprotein from Mycobacterium tuberculosis. INNATE IMMUNITY 2010 Aug;16(4):213-25.

Krummel B, Strassburg A, Ernst M, Reiling N, Eker B, Rath H, Hoerster R, Wappler W, Glaewe A, Schoellhorn V, Sotgiu G, Lange C. Potential Role for IL-2 ELISpot in Differentiating Recent and Remote Infection in Tuberculosis Contact Tracing. PLOS ONE 2010 Jul;5(7):e11670. Open Access

Selected Publications

Schaefer M, Reiling N, Fessler C, Stephani J, Taniuchi I, Hatam F, Yildirim A, Fehrenbach H, Walter K, Ruland J, Wagner H, Ehlers S, Sparwasser T. Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infection. JOURNAL OF IMMUNOLOGY 2008 May;180(10):6836-6845.

Holscher C, Reiling N, Schaible U, Holscher A, Bathmann C, Korbel D, Lenz I, Sonntag T, Kroger S, Akira S, Mossmann H, Kirschning C, Wagner H, Freudenberg M, Ehlers S. Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9. EUROPEAN JOURNAL OF IMMUNOLOGY 2008 Mar;38(3):680-694.

Reiling N, Ehlers S, Holscher C. MyDths and un-TOLLed truths: Sensor, instructive and effector immunity to tuberculosis. IMMUNOLOGY LETTERS 2008 Feb;116(1):15-23.

Wittkowski M, Mittelstadt J, Brandau S, Reiling N, Lindner B, Torrelles J, Brennan P, Holst O. Capsular arabinomannans from Mycobacterium avium with morphotype-specific structural differences but identical biological activity. JOURNAL OF BIOLOGICAL CHEMISTRY 2007 Jun;282(26):19103-19112.

Reiling N, Schneider D, Ehlers S. Mycobacterium tuberculosis-induced cell death of primary human monocytes and macrohages is not significantly modulated by tumor necrosis factor-targeted biologicals. JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS 2007 May;12(1):26-33.

Blumenthal A, Ehlers S, Lauber J, Buer J, Lange C, Goldmann T, Heine H, Brandt E, Reiling N. The Wingless homolog, WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. BLOOD 2006 Aug;108(3):965-973.

Blumenthal A, Lauber J, Hoffmann R, Ernst M, Keller C, Buer J, Ehlers S, Reiling N. Common and unique gene expression signatures of human macrophages in response to four strains of Mycobacterium avium that differ in their growth and persistence characteristics. INFECTION AND IMMUNITY 2005 Jun;73(6):3330-3341.

Valentonyte R, Hampe J, Huse K, Rosenstiel P, Albrecht M, Stenzel A, Nagy M, Gaede K, Franke A, Haesler R, Koch A, Lengauer T, Seegert D, Reiling N, Ehlers S, Schwinger E, Platzer M, Krawczak M, Muller-Quernheim J, Schurmann M, Schreiber S. Sarcoidosis is associated with a truncating splice site mutation in BTNL2. NATURE GENETICS 2005 Apr;37(4):357-364.

Rupp J, Berger M, Reiling N, Gieffers J, Lindschau C, Haller H, Dalhofff K, Maass M. Cox-2 inhibition abrogates Chlamydia pneumoniae-induced PGE(2) and MMP-1 expression. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2004 Jul;320(3):738-744.

Mailaender C, Reiling N, Engelhardt H, Bossmann S, Ehlers S, Niederweis M. The MspA porin promotes growth and increases antibiotic susceptibility of both Mycobacterium bovis BCG and Mycobacterium tuberculosis. MICROBIOLOGY-SGM 2004 Apr;150:853-864.

Reiling N, Holscher C, Fehrenbach A, Kroger S, Kirschning C, Goyert S, Ehlers S. Cutting edge: Toll-like receptor (TLR)2- and TLR4-mediated pathogen recognition in resistance to airborne infection with Mycobacterium tuberculosis. JOURNAL OF IMMUNOLOGY 2002 Oct;169(7):3480-3484.

Blumenthal A, Ehlers S, Ernst M, Flad H, Reiling N. Control of mycobacterial replication in human macrophages: Roles of extracellular signal-regulated kinases 1 and 2 and p38 mitogen-activated protein kinase pathways. INFECTION AND IMMUNITY 2002 Sep;70(9):4961-4967.

Reiling N, Klug K, Krallmann-Wenzel U, Laves R, Goyert S, Taylor M, Lindhorst T, Ehlers S. Complex encounters at the macrophage-mycobacterium interface: Studies on the role of the mannose receptor and CD14 in experimental infection models with Mycobacterium avium. IMMUNOBIOLOGY 2001 Dec;204(5):558-571.

Reiling N, Blumenthal A, Flad H, Ernst M, Ehlers S. Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity. JOURNAL OF IMMUNOLOGY 2001 Sep;167(6):3339-3345.